Isotope-Labeled Compounds

PDF 37.01 MB

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time.

MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds (12438):

Cat. No.	상품명	CAS No.	Purity	화학구조

HY-Y0520S

Itaconic acid-13C5	2095777-38-9	99.22%
Itaconic acid-¹³C₅ is the ¹³C labeled Itaconic acid. Itaconic acid, a precursor of polymers, chemicals, and fuels, can be synthesized by many fungi. Itaconic acid also is a macrophage-specific metabolite. Itaconic acid mediates crosstalk between macrophage metabolism and peritoneal tumors.

HY-N0322S1

Cholesterol-d6	60816-17-3	99.0%
Cholesterol-d₆ is the deuterium labeled Cholesterol. Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins. Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist.

HY-N0623S9

L-Tryptophan-d3	133519-78-5	99.98%
L-Tryptophan-d₃ is the deuterium labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3.

HY-N0728S3

α-Linolenic acid-13C18	287111-28-8	99.5%
α-Linolenic acid-¹³C₁₈ is the ¹³C labeled α-Linolenic acid. α-Linolenic acid, isolated from seed oils, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer.

HY-134928AS

Pyridinium bisretinoid A2E-d4 TFA
Pyridinium bisretinoid A2E-d₄ TFA is the deuterium-labeled Pyridinium bisretinoid A2E (HY-134928). Pyridinium bisretinoid A2E (A2E)is an initiator of blue-light-induced apoptosis. Photoactivation of Pyridinium bisretinoid A2E mediates autophagy and the production of reactive oxygen species.

HY-N0650S11

L-Serine-d7	935275-35-7	99.97%
L-Serine-d₇ is the deuterium labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-W016823S

p-Tyramine-d4 hydrochloride	1189884-47-6	≥99.90%
p-Tyramine-d₄ (hydrochloride) is the deuterium labeled Tyramine hydrochloride. Tyramine hydrochloride is an amino acid that helps regulate blood pressure. Tyramine hydrochloride occurs naturally in the body, and it's found in certain foods.

HY-W016562S1

Hippuric acid-d2	208928-78-3	99.85%
Hippuric acid-d₂ is the deuterium labeled Hippuric acid. Hippuric Acid (2-Benzamidoacetic acid), an acyl glycine produced by the conjugation of benzoic acid and glycine, is a normal component in urine as a metabolite of aromatic compounds from food.

HY-B0389S6

D-Glucose-d7	66034-51-3	99.94%
D-Glucose-d₇7 is the deuterium labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response.

HY-N0097S4

Guanosine-13C10
Guanosine-¹³C₁₀ is the ¹³C labeled Guanosine (HY-N0097). Guanosine is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Guanosine possesses anti-HSV activity.

HY-W011727S

Pyridoxal Phosphate-d3	1354560-58-9	98.01%
Pyridoxal Phosphate-d₃ is the deuterium labeled Pyridoxal 5'-phosphate. Pyridoxal 5'-phosphate, the active form of vitamin B6, is an essential cofactor for multiple enzymes, including aromatic l-amino acid decarboxylase that catalyzes the final stage in the production of the neurotransmitters dopamine and serotonin. Pyridoxal 5'-phosphate is the most important coenzyme variant in the process of vitamin B6 intracellular phosphorylation and is interconvertible with other variants, including pyridoxine 5′‐phosphate (PNP) and pyridoxamine 5′-phosphate (PMP).

HY-W016784S

Indole-3-acetamide-d5	1204700-53-7	99.99%
Indole-3-acetamide-d₅ is the deuterium labeled Indole-3-acetamide. Indole-3-acetamide is a biosynthesis intermediate of indole-3-acetic acid (HY-18569). Indole-3-acetic acid is the most common natural plant growth hormone of the auxin class.

HY-B0143S2

Niacin-d4	66148-15-0	99.71%
Niacin-d₄ is the deuterium labeled Niacin. Niacin (Nicotinic acid) is a vitamin and is part of the vitamin B group.

HY-B0282S1

Acetylcholine-d9 chloride	344298-95-9	99%
Acetylcholine-d₉ (chloride) is the deuterium labeled Acetylcholine chloride. Acetylcholine chloride (ACh chloride), a neurotransmitter, is a potent and BBB-permeable cholinergic agonist. Acetylcholine chloride is a modulator of the activity of dopaminergic (DAergic) neurons through the stimulation of nicotinic acetylcholine receptors (nAChRs). Acetylcholine chloride inhibits p53 mutant peptide aggregation in vitro.

HY-40135S

L-Hydroxyproline-d3	1356016-86-8	99.94%
L-Hydroxyproline-d₃ is the deuterium labeled L-Hydroxyproline. L-Hydroxyproline, one of the hydroxyproline (Hyp) isomers, is a useful chiral building block in the production of many pharmaceuticals.

HY-41417S

Octanoic acid-d15	69974-55-6	99.88%
Octanoic acid-d₁₅ is the deuterium labeled Octanoic acid. Octanoic acid (Caprylic acid) is an oily liquid with a slightly unpleasant rancid taste and used commercially in the production of esters used in perfumery and also in the manufacture of dyes.

HY-B0239S

Chloramphenicol-d5	202480-68-0	99.90%
Chloramphenicol-d₅ is the deuterium labeled Chloramphenicol. Chloramphenicol is a broad-spectrum antibiotic against bacterial infections.

HY-B0579S

Cyclosporin A-d4		99.59%
Cyclosporin A-d₄ is the deuterium labeled Cyclosporin A. Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of calcineurin with an IC50 of 5 nM. Cyclosporin A also inhibits CD11a/CD18 ad

HY-N0019S

Daidzein-d4	1219803-57-2	98.93%
Daidzein-d₄ is the deuterium labeled Daidzein. Daidzein is a soy isoflavone, which acts as a PPAR activator.

HY-N0437S

Progesterone-d9	15775-74-3	≥98.0%
Progesterone-d₉ is the deuterium labeled Progesterone. Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.

Name
이메일 *

	Sorry, but the email address you supplied was invalid.