Pyridoxal Phosphate-d3
Based on 1 Customer Validation
Pyridoxal Phosphate-d3 is the deuterium labeled Pyridoxal 5'-phosphate. Pyridoxal 5'-phosphate, the active form of vitamin B6, is an essential cofactor for multiple enzymes, including aromatic l-amino acid decarboxylase that catalyzes the final stage in the production of the neurotransmitters dopamine and serotonin. Pyridoxal 5'-phosphate is the most important coenzyme variant in the process of vitamin B6 intracellular phosphorylation and is interconvertible with other variants, including pyridoxine 5′‐phosphate (PNP) and pyridoxamine 5′-phosphate (PMP).
For research use only. We do not sell to patients.
- Purity: 98.01%
- CAS No.: 1354560-58-9
- Formula: C8H7D3NO6P
- Molecular Weight:250.16
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1354560-58-9
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Unlabeled Cas 853645-22-4
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Appearance Solid
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Molecular Weight 250.16
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Formula C8H7D3NO6P
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Color White to off-white
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SMILES
O=CC1=C(O)C(C([2H])([2H])[2H])=NC=C1COP(O)(O)=O
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Synonyms
Pyridoxal 5'-phosphate-d3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 62.5 mg/mL (249.84 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.9974 mL | 19.9872 mL | 39.9744 mL | 99.9360 mL |
| 5 mM | 0.7995 mL | 3.9974 mL | 7.9949 mL | 19.9872 mL | |
| 10 mM | 0.3997 mL | 1.9987 mL | 3.9974 mL | 9.9936 mL | |
| 15 mM | 0.2665 mL | 1.3325 mL | 2.6650 mL | 6.6624 mL | |
| 20 mM | 0.1999 mL | 0.9994 mL | 1.9987 mL | 4.9968 mL | |
| 25 mM | 0.1599 mL | 0.7995 mL | 1.5990 mL | 3.9974 mL | |
| 30 mM | 0.1332 mL | 0.6662 mL | 1.3325 mL | 3.3312 mL | |
| 40 mM | 0.0999 mL | 0.4997 mL | 0.9994 mL | 2.4984 mL | |
| 50 mM | 0.0799 mL | 0.3997 mL | 0.7995 mL | 1.9987 mL | |
| 60 mM | 0.0666 mL | 0.3331 mL | 0.6662 mL | 1.6656 mL | |
| 80 mM | 0.0500 mL | 0.2498 mL | 0.4997 mL | 1.2492 mL | |
| 100 mM | 0.0400 mL | 0.1999 mL | 0.3997 mL | 0.9994 mL |
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