p-Tyramine-d₄ hydrochloride

Name: p-Tyramine-d 4 hydrochloride
Brand: MedChemExpress
SKU: HY-W016823S
Rating: 4.5 (1 reviews)

Cat. No.: HY-W016823S Purity: 99.52%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

p-Tyramine-d₄ (hydrochloride) is the deuterium labeled Tyramine hydrochloride. Tyramine hydrochloride is an amino acid that helps regulate blood pressure. Tyramine hydrochloride occurs naturally in the body, and it's found in certain foods[1][2].

For research use only. We do not sell to patients.

p-Tyramine-d<sub>4</sub> hydrochloride Chemical Structure

p-Tyramine-d₄ hydrochloride Chemical Structure

CAS No. : 1189884-47-6

Size	Price	Stock	Quantity
1 mg	USD 140	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 590	In-stock	Estimated Time of Arrival: December 31
10 mg		Get quote
50 mg		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of p-Tyramine-d₄ hydrochloride:

Tyramine hydrochloride In-stock

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Biological Activity
Purity & Documentation
References
Customer Review

Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

177.66

Formula

C₈H₈D₄ClNO

CAS No.

1189884-47-6

Appearance

Solid

Color

White to off-white

SMILES

OC1=CC=C(C([2H])([2H])C([2H])([2H])N)C=C1.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (562.87 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.6287 mL	28.1436 mL	56.2873 mL
5 mM	1.1257 mL	5.6287 mL	11.2575 mL
10 mM	0.5629 mL	2.8144 mL	5.6287 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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Dosing volume
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μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.52%

Select Batch:

Data Sheet (270 KB) SDS (393 KB)

COA (246 KB) HNMR (130 KB) RP-HPLC (247 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

[2]. C Brown , et al. The Monoamine Oxidase Inhibitor-Tyramine Interaction. J Clin Pharmacol. 1989 Jun;29(6):529-32. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	5.6287 mL	28.1436 mL	56.2873 mL	140.7182 mL
	5 mM	1.1257 mL	5.6287 mL	11.2575 mL	28.1436 mL
	10 mM	0.5629 mL	2.8144 mL	5.6287 mL	14.0718 mL
	15 mM	0.3752 mL	1.8762 mL	3.7525 mL	9.3812 mL
	20 mM	0.2814 mL	1.4072 mL	2.8144 mL	7.0359 mL
	25 mM	0.2251 mL	1.1257 mL	2.2515 mL	5.6287 mL
	30 mM	0.1876 mL	0.9381 mL	1.8762 mL	4.6906 mL
	40 mM	0.1407 mL	0.7036 mL	1.4072 mL	3.5180 mL
	50 mM	0.1126 mL	0.5629 mL	1.1257 mL	2.8144 mL
	60 mM	0.0938 mL	0.4691 mL	0.9381 mL	2.3453 mL
	80 mM	0.0704 mL	0.3518 mL	0.7036 mL	1.7590 mL
	100 mM	0.0563 mL	0.2814 mL	0.5629 mL	1.4072 mL