ML120 analog 1

Cat. No.: HY-127178 Purity: 99.63%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

ML120 analog 1 (compound 1) is a competitive inhibitor with a K_i of 0.69 μM for Hematopoietic protein tyrosine phosphatase (HePTP).

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

ML120 analog 1 화학구조

CAS No. : 445426-74-4

사이즈	재고	수량
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	해외재고보유	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	해외재고보유	Estimated Time of Arrival: December 31
Solid
5 mg	해외재고보유	Estimated Time of Arrival: December 31
10 mg	해외재고보유	Estimated Time of Arrival: December 31
25 mg	해외재고보유	Estimated Time of Arrival: December 31
50 mg	해외재고보유	Estimated Time of Arrival: December 31
100 mg	해외재고보유	Estimated Time of Arrival: December 31
200 mg	견적 받기
500 mg	견적 받기

or 대량구매 문의

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

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Biological Activity
순도&문서
References
고객리뷰

제품 설명

ML120 analog 1 (compound 1) is a competitive inhibitor with a K_i of 0.69 μM for Hematopoietic protein tyrosine phosphatase (HePTP)^[1].

IC₅₀ & Target

Ki: 0.69 μM(compound 1)^[1]

분자량

526.99

화학식

C₂₆H₂₃ClN₂O₆S

CAS No.

445426-74-4

Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C(C1=C(C)N=C(S/C(C2=O)=C/C3=CC=C(OCC(O)=O)C=C3)N2C1C4=CC=C(Cl)C=C4)OC(C)C

선적

Room temperature in continental US; may vary elsewhere.

보관

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

용액&용해도

In Vitro:

DMSO : 10 mg/mL (18.98 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.8976 mL	9.4878 mL	18.9757 mL
5 mM	0.3795 mL	1.8976 mL	3.7951 mL
10 mM	0.1898 mL	0.9488 mL	1.8976 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

몰농도 계산기
농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

순도&문서

Purity: 99.63%

Select Batch:

Data Sheet (271 KB) SDS (252 KB)

COA (250 KB) HNMR (308 KB) RP-HPLC (259 KB) MS (231 KB)

Handling Instructions (2659 KB)

References

[1]. Bobkova EV, et al. Inhibition of the Hematopoietic Protein Tyrosine Phosphatase by Phenoxyacetic Acids. ACS Med Chem Lett. 2011 Feb;2(2):113-118. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.8976 mL	9.4878 mL	18.9757 mL	47.4392 mL
	5 mM	0.3795 mL	1.8976 mL	3.7951 mL	9.4878 mL
	10 mM	0.1898 mL	0.9488 mL	1.8976 mL	4.7439 mL
	15 mM	0.1265 mL	0.6325 mL	1.2650 mL	3.1626 mL

ML120 analog 1 Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ML120 analog 1445426-74-4Phosphatasehematopoietic protein tyrosine phosphataseinhibitoranalogInhibitorinhibit

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ML120 analog 1

ML120 analog 1 Related Antibodies

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