1. Cell Cycle/DNA Damage
  2. DNA/RNA Synthesis
  3. N-Dodecyl-β-D-maltoside

N-Dodecyl-β-D-maltoside  (Synonyms: Lauryl Maltoside)

Art. -Nr.: HY-128974 Reinheit: 99.97%
Handling Instructions Technical Support

N-Dodecyl-β-D-maltoside (Lauryl Maltoside) is a non-ionic detergent. N-Dodecyl-β-D-maltoside has strong adsorption on alumina, titanium dioxide and hematite. N-Dodecyl-β-D-maltoside can promote the reactivation of various proteins. N-Dodecyl-β-D-maltoside can effectively stabilize photoactive reaction center complexes (RCs) and inhibit the degradation of Rhodopseudomonas spheroides R-26 reaction center in solution. N-Dodecyl-β-D-maltoside can be used for purification and stabilization of RNA polymerase and for detection of protein-lipid interactions.

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CAS. Nr. : 69227-93-6

Größe Preis Verfügbarkeit Menge
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water
ready for reconstitution
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Solution
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Based on 5 publication(s) in Google Scholar

Other Forms of N-Dodecyl-β-D-maltoside:

Top Publications Citing Use of Products

    N-Dodecyl-β-D-maltoside purchased from MedChemExpress. Usage Cited in: EMBO J. 2025 Aug 26.  [Abstract]

    BNE and immunoblotting analysis of DDM (2  mg/mg protein)-solubilised mitochondrial membranes from WT and RTN4IP1KO U2OS lines using antibodies against complexes I (NDUFV1), II (SDHA, loading control) and V (ATP5A).

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    Beschreibung

    N-Dodecyl-β-D-maltoside (Lauryl Maltoside) is a non-ionic detergent. N-Dodecyl-β-D-maltoside has strong adsorption on alumina, titanium dioxide and hematite. N-Dodecyl-β-D-maltoside can promote the reactivation of various proteins. N-Dodecyl-β-D-maltoside can effectively stabilize photoactive reaction center complexes (RCs) and inhibit the degradation of Rhodopseudomonas spheroides R-26 reaction center in solution. N-Dodecyl-β-D-maltoside can be used for purification and stabilization of RNA polymerase and for detection of protein-lipid interactions[1][2][3][4].

    In Vitro

    N-Dodecyl-β-D-maltosid (0.02-10 mg/mL; 90 min) can promote the reactivation of denatured adenosine deaminase, 3-phosphoglycerol phosphokinase, myokinase and 3-hydroxysteroid dehydrogenase in the denatured enzyme dilutive solution (The enzyme activity reaches the maximum at 0.06 mg/mL, and the enzyme activity reaches 98%), but doesn’t significantly reactivate phosphoglucomutase[1].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    Molekulargewicht

    510.62

    Formel

    C24H46O11

    CAS. Nr.
    Appearance

    Solid

    Color

    White to off-white

    SMILES

    OC[C@H]([C@@H](O)[C@H](O)[C@H]1O)O[C@]1([H])O[C@@H]2[C@H](O[C@@H](OCCCCCCCCCCCC)[C@H](O)[C@H]2O)CO

    Versand

    Room temperature in continental US; may vary elsewhere.

    Speicherung
    Powder -20°C 3 years
    4°C 2 years
    In solvent -80°C 6 months
    -20°C 1 month
    Lösungsmittel & Löslichkeit
    In Vitro: 

    H2O : 50 mg/mL (97.92 mM; Need ultrasonic)

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 1.9584 mL 9.7920 mL 19.5840 mL
    5 mM 0.3917 mL 1.9584 mL 3.9168 mL
    View the Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

    • Molaritätsrechner

    • Verdünnungsrechner

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

    Mass
    =
    Concentration
    ×
    Volume
    ×
    Molecular Weight *

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    This equation is commonly abbreviated as: C1V1 = C2V2

    Concentration (start)

    C1

    ×
    Volume (start)

    V1

    =
    Concentration (final)

    C2

    ×
    Volume (final)

    V2

    In Vivo:

    For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
    The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

    • Protocol 1

      Add each solvent one by one:  PBS

      Solubility: 100 mg/mL (195.84 mM); Clear solution; Need ultrasonic and warming and heat to 60°C

    In Vivo Dissolution Calculator
    Please enter the basic information of animal experiments:

    Dosage

    mg/kg

    Animal weight
    (per animal)

    g

    Dosing volume
    (per animal)

    μL

    Number of animals

    Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
    Calculation results:
    Working solution concentration: mg/mL
    This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
    The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
    Reinheit & Dokumentation

    Purity: 99.97%

    Verweise

    Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

    Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
    H2O 1 mM 1.9584 mL 9.7920 mL 19.5840 mL 48.9601 mL
    5 mM 0.3917 mL 1.9584 mL 3.9168 mL 9.7920 mL
    10 mM 0.1958 mL 0.9792 mL 1.9584 mL 4.8960 mL
    15 mM 0.1306 mL 0.6528 mL 1.3056 mL 3.2640 mL
    20 mM 0.0979 mL 0.4896 mL 0.9792 mL 2.4480 mL
    25 mM 0.0783 mL 0.3917 mL 0.7834 mL 1.9584 mL
    30 mM 0.0653 mL 0.3264 mL 0.6528 mL 1.6320 mL
    40 mM 0.0490 mL 0.2448 mL 0.4896 mL 1.2240 mL
    50 mM 0.0392 mL 0.1958 mL 0.3917 mL 0.9792 mL
    60 mM 0.0326 mL 0.1632 mL 0.3264 mL 0.8160 mL
    80 mM 0.0245 mL 0.1224 mL 0.2448 mL 0.6120 mL

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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    N-Dodecyl-β-D-maltoside Related Classifications

    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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    Produktname:
    N-Dodecyl-β-D-maltoside
    Art. -Nr.:
    HY-128974
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