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  5. N-Ethyl-N-nitrosourea

N-Ethyl-N-nitrosourea  (Synonyms: ENU; N-Nitroso-N-ethylurea)

製品番号: HY-W019815 純度: 99.92%
COA 取扱説明書 Technical Support

N-Ethyl-N-nitrosourea (ENU) is a DNA alkylating agent. N-Ethyl-N-nitrosourea induces leukemia by alkylating nucleobases, disrupting DNA, and resulting in bone marrow suppression and the formation of leukemic cells. N-Ethyl-N-nitrosourea is teratogenic in vivo, inducing tumor formation and paw malformations in pregnant rats. N-Ethyl-N-nitrosourea cause central nervous system (CNS) tumors and genetic disorders.

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N-Ethyl-N-nitrosourea

N-Ethyl-N-nitrosourea 構造式

CAS 番号 : 759-73-9

容量 価格（税別） 在庫状況 数量
250 mg $41 在庫あり
1 g $110 在庫あり
5 g $330 在庫あり
10 g $577 在庫あり
50 g   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

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N-Ethyl-N-nitrosourea 関連抗体

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DNA/RNA Synthesis アイソフォーム固有の製品をすべて表示:

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製品説明

N-Ethyl-N-nitrosourea (ENU) is a DNA alkylating agent. N-Ethyl-N-nitrosourea induces leukemia by alkylating nucleobases, disrupting DNA, and resulting in bone marrow suppression and the formation of leukemic cells. N-Ethyl-N-nitrosourea is teratogenic in vivo, inducing tumor formation and paw malformations in pregnant rats. N-Ethyl-N-nitrosourea cause central nervous system (CNS) tumors and genetic disorders[1][2].

体内実験

Note:
Please do not refer to only one article to determine the experimental conditions. It is recommended to determine the optimal experimental conditions (animal strain, age, dosage, frequency and cycle, detection time and indicators, etc.) through preliminary experiments before the formal experiment.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

117.11

分子式

C3H7N3O2
CAS 番号
Appearance

Solid

Color

Off-white to pink

SMILES

O=NN(CC)C(N)=O
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

-20°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
溶剤 & 溶解度
体外: 

DMSO : 116.67 mg/mL (996.24 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 8.5390 mL 42.6949 mL 85.3898 mL
5 mM 1.7078 mL 8.5390 mL 17.0780 mL
10 mM 0.8539 mL 4.2695 mL 8.5390 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始）

C1

×
体積 （開始）

V1

=
濃度 （終了）

C2

×
体積 （終了）

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
純度とドキュメンテーション

純度: 99.92%

COA (245 KB) HNMR (228 KB) RP-HPLC (257 KB)

取扱説明書 (2659 KB)
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 8.5390 mL 42.6949 mL 85.3898 mL 213.4745 mL
5 mM 1.7078 mL 8.5390 mL 17.0780 mL 42.6949 mL
10 mM 0.8539 mL 4.2695 mL 8.5390 mL 21.3475 mL
15 mM 0.5693 mL 2.8463 mL 5.6927 mL 14.2316 mL
20 mM 0.4269 mL 2.1347 mL 4.2695 mL 10.6737 mL
25 mM 0.3416 mL 1.7078 mL 3.4156 mL 8.5390 mL
30 mM 0.2846 mL 1.4232 mL 2.8463 mL 7.1158 mL
40 mM 0.2135 mL 1.0674 mL 2.1347 mL 5.3369 mL
50 mM 0.1708 mL 0.8539 mL 1.7078 mL 4.2695 mL
60 mM 0.1423 mL 0.7116 mL 1.4232 mL 3.5579 mL
80 mM 0.1067 mL 0.5337 mL 1.0674 mL 2.6684 mL
100 mM 0.0854 mL 0.4269 mL 0.8539 mL 2.1347 mL
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N-Ethyl-N-nitrosourea Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

N-Ethyl-N-nitrosourea759-73-9ENU N-Nitroso-N-ethylureaDNA/RNA SynthesisDNA alkylating agentleukemiateratogenicratsCNSInhibitorinhibitorinhibit

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製品名:
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製品番号:
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