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  3. N6-Methyladenosine-d3

N6-Methyladenosine-d3  (Synonyms: 6-Methyladenosine-d3; N-Methyladenosine-d3)

製品番号: HY-N0086S 純度: 99.97%
COA 取扱説明書 Technical Support

N6-Methyladenosine-d3 (6-Methyladenosine-d3; N-Methyladenosine-d3) is a deuterium labeled N6-Methyladenosine (HY-N0086). N6-Methyladenosine is the most prevalent internal (non-cap) modification present in the messenger RNA (mRNA) of all higher eukaryotes. N6-Methyladenosine can modifies viral RNAs and has antiviral activities.

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N6-Methyladenosine-d<sub>3</sub>

N6-Methyladenosine-d3 構造式

CAS 番号 : 139896-43-8

容量 価格(税別) 在庫状況 数量
1 mg $190 在庫あり
5 mg $418 在庫あり
10 mg   お問い合わせ  
50 mg   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

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カスタマーレビュー

Based on 0 publication(s) in Google Scholar

Other Forms of N6-Methyladenosine-d3:

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Endogenous Metabolite アイソフォーム固有の製品をすべて表示:

  • 生物活性

  • 純度とドキュメンテーション

  • 参考文献

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製品説明

N6-Methyladenosine-d3 (6-Methyladenosine-d3; N-Methyladenosine-d3) is a deuterium labeled N6-Methyladenosine (HY-N0086). N6-Methyladenosine is the most prevalent internal (non-cap) modification present in the messenger RNA (mRNA) of all higher eukaryotes. N6-Methyladenosine can modifies viral RNAs and has antiviral activities.

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

体外実験

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

284.29

分子式

C11H12D3N5O4

CAS 番号
Unlabeled CAS
Appearance

Solid

Color

White to off-white

SMILES

OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(N=CN=C3NC([2H])([2H])[2H])=C3N=C2)O1

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

溶剤 & 溶解度
体外: 

DMSO : 100 mg/mL (351.75 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.5175 mL 17.5877 mL 35.1753 mL
5 mM 0.7035 mL 3.5175 mL 7.0351 mL
10 mM 0.3518 mL 1.7588 mL 3.5175 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます:C1V1 = C2V2

濃度 (開始)

C1

×
体積 (開始)

V1

=
濃度 (終了)

C2

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体積 (終了)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Calculation results:
Working solution concentration: mg/mL
純度とドキュメンテーション

純度: 99.97%

参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.5175 mL 17.5877 mL 35.1753 mL 87.9384 mL
5 mM 0.7035 mL 3.5175 mL 7.0351 mL 17.5877 mL
10 mM 0.3518 mL 1.7588 mL 3.5175 mL 8.7938 mL
15 mM 0.2345 mL 1.1725 mL 2.3450 mL 5.8626 mL
20 mM 0.1759 mL 0.8794 mL 1.7588 mL 4.3969 mL
25 mM 0.1407 mL 0.7035 mL 1.4070 mL 3.5175 mL
30 mM 0.1173 mL 0.5863 mL 1.1725 mL 2.9313 mL
40 mM 0.0879 mL 0.4397 mL 0.8794 mL 2.1985 mL
50 mM 0.0704 mL 0.3518 mL 0.7035 mL 1.7588 mL
60 mM 0.0586 mL 0.2931 mL 0.5863 mL 1.4656 mL
80 mM 0.0440 mL 0.2198 mL 0.4397 mL 1.0992 mL
100 mM 0.0352 mL 0.1759 mL 0.3518 mL 0.8794 mL
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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます:C1V1 = C2V2

濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

製品名:
N6-Methyladenosine-d3
製品番号:
HY-N0086S
数量:
MCE 日本正規代理店: