1. Metabolic Enzyme/Protease
  2. Aminopeptidase
  3. NGR peptide

NGR peptide containing the Asn-Gly-Arg (NGR) motif. NGR peptide binds to APN/CD13. NGR peptide is directly conjugated to imaging agents that can be used for tumor imaging.

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NGR peptide

NGR peptide 構造式

CAS 番号 : 651328-78-8

容量 価格(税別) 在庫状況 数量
5 mg $90 在庫あり
10 mg $140 在庫あり
50 mg   お問い合わせ  
100 mg   お問い合わせ  

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Based on 1 publication(s) in Google Scholar

Other Forms of NGR peptide:

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Aminopeptidase アイソフォーム固有の製品をすべて表示:

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製品説明

NGR peptide containing the Asn-Gly-Arg (NGR) motif. NGR peptide binds to APN/CD13. NGR peptide is directly conjugated to imaging agents that can be used for tumor imaging[1][2].

IC50 & Target[1][2]

CD13

 

体内実験

NGR peptide (20 mg/kg; i.v.) can be used as a potential SPECT agent for imaging and early diagnosis of tumor[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 4-6 weeks, BALB/c nude mice (HepG2 tumor model)[2]
Dosage: 20 mg/kg
Administration: I.v.
Result: Blocked the tumor uptake for 99mTc-NGR.
分子量

608.69

分子式

C20H36N10O8S2

CAS 番号
Appearance

Solid

Color

White to off-white

Sequence

Cys-Asn-Gly-Arg-Cys-Gly

Sequence Shortening

CNGRCG

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件
Sealed storage, away from moisture
Powder -80°C 2 years
  -20°C 1 year
In solvent -80°C 6 months
  -20°C 1 month
溶剤 & 溶解度
体外: 

DMSO : 100 mg/mL (164.29 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.6429 mL 8.2144 mL 16.4287 mL
5 mM 0.3286 mL 1.6429 mL 3.2857 mL
10 mM 0.1643 mL 0.8214 mL 1.6429 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます:C1V1 = C2V2

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In Vivo Dissolution Calculator
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純度とドキュメンテーション
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.6429 mL 8.2144 mL 16.4287 mL 41.0718 mL
5 mM 0.3286 mL 1.6429 mL 3.2857 mL 8.2144 mL
10 mM 0.1643 mL 0.8214 mL 1.6429 mL 4.1072 mL
15 mM 0.1095 mL 0.5476 mL 1.0952 mL 2.7381 mL
20 mM 0.0821 mL 0.4107 mL 0.8214 mL 2.0536 mL
25 mM 0.0657 mL 0.3286 mL 0.6571 mL 1.6429 mL
30 mM 0.0548 mL 0.2738 mL 0.5476 mL 1.3691 mL
40 mM 0.0411 mL 0.2054 mL 0.4107 mL 1.0268 mL
50 mM 0.0329 mL 0.1643 mL 0.3286 mL 0.8214 mL
60 mM 0.0274 mL 0.1369 mL 0.2738 mL 0.6845 mL
80 mM 0.0205 mL 0.1027 mL 0.2054 mL 0.5134 mL
100 mM 0.0164 mL 0.0821 mL 0.1643 mL 0.4107 mL
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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます:C1V1 = C2V2

濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

製品名:
NGR peptide
製品番号:
HY-P1043
数量:
MCE 日本正規代理店: