1. GPCR/G Protein
  2. Angiotensin Receptor
  3. Perindopril arginine

Perindopril arginine is an angiotensin-converting enzyme inhibitor with hypotensive activity. Perindopril arginine is used to inhibit hypertension to lower blood pressure. Perindopril arginine, when used in combination with indapamide and amlodipine, can effectively lower blood pressure and provide better target organ protection.

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Perindopril arginine

Perindopril arginine 構造式

CAS 番号 : 612548-45-5

容量 価格(税別) 在庫状況
1 g $75 見積もりとリードタイムを求めるのご確認
5 g $260 見積もりとリードタイムを求めるのご確認

* アイテムを追加する前、数量をご選択ください

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製品説明

Perindopril arginine is an angiotensin-converting enzyme inhibitor with hypotensive activity. Perindopril arginine is used to inhibit hypertension to lower blood pressure. Perindopril arginine, when used in combination with indapamide and amlodipine, can effectively lower blood pressure and provide better target organ protection[1].

臨床実験
分子量

542.67

分子式

C25H46N6O7

CAS 番号
Appearance

Solid

Color

White to off-white

SMILES

N=C(N)NCCC[C@H](N)C(O)=O.CCOC([C@H](CCC)N[C@@H](C)C(N1[C@]2([H])[C@](CCCC2)([H])C[C@H]1C(O)=O)=O)=O

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶剤 & 溶解度
体外: 

H2O : ≥ 100 mg/mL (184.27 mM)

DMSO : 6.48 mg/mL (11.94 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8427 mL 9.2137 mL 18.4274 mL
5 mM 0.3685 mL 1.8427 mL 3.6855 mL
10 mM 0.1843 mL 0.9214 mL 1.8427 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます:C1V1 = C2V2

濃度 (開始)

C1

×
体積 (開始)

V1

=
濃度 (終了)

C2

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体積 (終了)

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
純度とドキュメンテーション
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / H2O 1 mM 1.8427 mL 9.2137 mL 18.4274 mL 46.0685 mL
5 mM 0.3685 mL 1.8427 mL 3.6855 mL 9.2137 mL
10 mM 0.1843 mL 0.9214 mL 1.8427 mL 4.6069 mL
H2O 15 mM 0.1228 mL 0.6142 mL 1.2285 mL 3.0712 mL
20 mM 0.0921 mL 0.4607 mL 0.9214 mL 2.3034 mL
25 mM 0.0737 mL 0.3685 mL 0.7371 mL 1.8427 mL
30 mM 0.0614 mL 0.3071 mL 0.6142 mL 1.5356 mL
40 mM 0.0461 mL 0.2303 mL 0.4607 mL 1.1517 mL
50 mM 0.0369 mL 0.1843 mL 0.3685 mL 0.9214 mL
60 mM 0.0307 mL 0.1536 mL 0.3071 mL 0.7678 mL
80 mM 0.0230 mL 0.1152 mL 0.2303 mL 0.5759 mL
100 mM 0.0184 mL 0.0921 mL 0.1843 mL 0.4607 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます:C1V1 = C2V2

濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

製品名:
Perindopril arginine
製品番号:
HY-169221
数量:
MCE 日本正規代理店: