1. Metabolic Enzyme/Protease
  2. Phosphatase
  3. PRL-3 Inhibitor I

PRL-3 Inhibitor I is a potent PRL-3 inhibitor with an IC50 of 0.9 μM. PRL-3 Inhibitor I shows a reduced invasion in cell-based assay.

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PRL-3 Inhibitor I

PRL-3 Inhibitor I 構造式

CAS 番号 : 893449-38-2

容量 価格(税別) 在庫状況 数量
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
USD 27 在庫あり
Solution
10 mM * 1 mL in DMSO USD 27 在庫あり
Solid
5 mg $25 在庫あり
10 mg $40 在庫あり
25 mg $85 在庫あり
50 mg $135 在庫あり
100 mg $220 在庫あり
200 mg   お問い合わせ  
500 mg   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

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Based on 1 publication(s) in Google Scholar

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製品説明

PRL-3 Inhibitor I is a potent PRL-3 inhibitor with an IC50 of 0.9 μM. PRL-3 Inhibitor I shows a reduced invasion in cell-based assay[1].

IC50 & Target

IC50: 0.9 μM (PRL-3)[1]

Cellular Effect
Cell Line Type Value Description References
DLD-1 IC50
7 μM
Compound: BR-1
Antimigratory activity against human DLD1 cells overexpressing PRL3 by crystal violet staining-based light microscopic analysis
Antimigratory activity against human DLD1 cells overexpressing PRL3 by crystal violet staining-based light microscopic analysis
[PMID: 23726031]
体外実験

PRL-3 Inhibitor I (compound 5e) reduces the invasion of mouse melanoma B16F10 cells in a cell-based assay[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

485.21

分子式

C17H11Br2NO2S2

CAS 番号
Appearance

Solid

Color

Light yellow to green yellow

SMILES

O=C1NC(S/C1=C/C2=CC(Br)=CC=C2OCC3=CC=CC=C3Br)=S

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

溶剤 & 溶解度
体外: 

DMSO : 41.67 mg/mL (85.88 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : < 0.1 mg/mL (insoluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0610 mL 10.3048 mL 20.6096 mL
5 mM 0.4122 mL 2.0610 mL 4.1219 mL
10 mM 0.2061 mL 1.0305 mL 2.0610 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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一般には略語で表示されます:C1V1 = C2V2

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In Vivo Dissolution Calculator
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純度とドキュメンテーション
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.0610 mL 10.3048 mL 20.6096 mL 51.5241 mL
5 mM 0.4122 mL 2.0610 mL 4.1219 mL 10.3048 mL
10 mM 0.2061 mL 1.0305 mL 2.0610 mL 5.1524 mL
15 mM 0.1374 mL 0.6870 mL 1.3740 mL 3.4349 mL
20 mM 0.1030 mL 0.5152 mL 1.0305 mL 2.5762 mL
25 mM 0.0824 mL 0.4122 mL 0.8244 mL 2.0610 mL
30 mM 0.0687 mL 0.3435 mL 0.6870 mL 1.7175 mL
40 mM 0.0515 mL 0.2576 mL 0.5152 mL 1.2881 mL
50 mM 0.0412 mL 0.2061 mL 0.4122 mL 1.0305 mL
60 mM 0.0343 mL 0.1717 mL 0.3435 mL 0.8587 mL
80 mM 0.0258 mL 0.1288 mL 0.2576 mL 0.6441 mL
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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます:C1V1 = C2V2

濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

製品名:
PRL-3 Inhibitor I
製品番号:
HY-112476
数量:
MCE 日本正規代理店: