2. Cell Cycle/DNA Damage Others
  3. Topoisomerase Drug Isomer
  4. (R)-Camptothecin

(R)-Camptothecin  (Synonyms: (R)-Campathecin; (R)-(+)-Camptothecin; (R)-CPT)

Cat. No.: HY-16560B
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(R)-Camptothecin is an enantiomer of Camptothecin (CPT), is inactive as an inhibitor of the DNA religation reaction and consequently do not poison Top1.

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(R)-Camptothecin

(R)-Camptothecin Chemical Structure

CAS No. : 110351-92-3

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Other Forms of (R)-Camptothecin:

(R)-Camptothecin Related Antibodies

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Description

(R)-Camptothecin is an enantiomer of Camptothecin (CPT), is inactive as an inhibitor of the DNA religation reaction and consequently do not poison Top1[1].

Cellular Effect
Cell Line Type Value Description References
HL-60 IC50
>30 μM
Compound: 5ao
Inhibition of Topoisomerase I by cleavage complex formation in human HL-60 cells
Inhibition of Topoisomerase I by cleavage complex formation in human HL-60 cells
[PMID: 8410981]
Masse moléculaire

348.35

Formule

C20H16N2O4
CAS No.
SMILES

CC[C@]1(C2=C(COC1=O)C(N3C(C4=NC5=CC=CC=C5C=C4C3)=C2)=O)O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
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(R)-Camptothecin Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(R)-Camptothecin110351-92-3(R)-Campathecin (R)-(+)-Camptothecin (R)-CPTTopoisomeraseDrug IsomerInhibitorinhibitorinhibit

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