Search Result

Results for "

Cannabinoid+Receptor+1

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Cannabinoid Receptor (15) Arrestin (1) Biochemical Assay Reagents (1) CETP (1) Endogenous Metabolite (1) FAAH (1) MHC (1) NF-κB (1) p38 MAPK (1)
By Research Areas:	Cancer (1) Inflammation/Immunology (5) Metabolic Disease (5) Neurological Disease (8)

Inhibitors & Agonists

Natural
Products

Recombinant Proteins

Antibodies

Targets Recommended: Cannabinoid Receptor

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-153800

Monlunabant 1 Publications Verification (S)-MRI-1891; INV-202	Cannabinoid Receptor Arrestin	Metabolic Disease
Monlunabant ((S)-MRI-1891) is an orally active antagonist for *cannabinoid receptor 1* (CB1), binds to *hCB1* and hCB2 with K_i of 0.3 nM and 613 nM ^[1].

HY-112340

CB1 antagonist 4	Cannabinoid Receptor	Neurological Disease Metabolic Disease
CB1 antagonist 4 (compound 8) is a selective cannabinoid receptor 1 (CB1) inverse agonist with an IC₅₀ of 8.5 nM for human CB1. CB1 antagonist 4 shows selective for CB1 over CB2 receptors (IC₅₀ of 604.9 nM). CB1 antagonist 4 inhibits GTP binding to CB1-overexpressing cell membranes with an EC₅₀ of 18.5 nM ^[1].

HY-177425

AM11542	Cannabinoid Receptor	Metabolic Disease
AM11542 is a *cannabinoid receptor 1* (CB1) agonist with a human CB1 K_i of 0.11 nM. AM11542 stabilizes the active conformational state of the CB1 receptor. AM11542 can be used for the research of obesity ^[1].

HY-171883

BI-5756	Cannabinoid Receptor CETP MHC	Metabolic Disease Inflammation/Immunology Cancer
BI-5756 is a CETP inhibitor and cannabinoid receptor 1 (CB1) agonist. BI-5756 can significantly increase HDL-C levels and reduce LDL-C levels. BI-5756 can also enhance the function of regulatory T cells while maintaining T cell-mediated anti-tumor activity. BI-5756 can directly inhibit the growth of tumor cells and upregulate the expression of MHC I, MHC II, and CD80 on tumor cells. BI-5756 has a protective effect in graft-versus-host disease models. BI-5756 can be used in research on tumors, graft-versus-host disease, and metabolic diseases ^[1].

HY-174335

UVI3502	Cannabinoid Receptor	Neurological Disease
UVI3502 is a cannabinoid receptor 1 (CB1) antagonist with an IC₅₀ value of 4641 nM for CB1 and approximately 16200 nM for CB2. UVI3502 blocks G_i/o protein coupling induced by the agonist CP55,940. UVI3502 is promising for research of endocannabinoid system-related diseases in the central nervous system (such as cognitive impairment and neurodegenerative diseases) ^[1].

HY-121545

CB-52	Cannabinoid Receptor	Inflammation/Immunology
CB-52 is the ligand and neutral antagonist of CB2 cannabinoid receptor .

HY-120953

GAT228	Cannabinoid Receptor	Inflammation/Immunology
GAT228, the enantiomer of GAT211, is an allosteric **cannabinoid receptor 1 (CB1)** ligand ^[1].

HY-167865

O-1269	Cannabinoid Receptor	Neurological Disease
O-1269 is a partial agonist of **cannabinoid receptor 1 (CB1R) with a K_i** of 32 nM. O-1269 shows analgesic effects ^[1].

HY-121616

(R)-SLV 319	Cannabinoid Receptor	Neurological Disease
(R)-SLV 319 is a potent and selective **cannabinoid receptor 1 (CB1) antagonist with a K_i** value of 894 nM. (R)-SLV 319 is a dextrorotatory counterpart of SLV 319 ^[1]

HY-103326

NIDA-41020	Cannabinoid Receptor	Neurological Disease
NIDA-41020 is a potent and selective *cannabinoid receptor 1(CB1)* antagonist with a K_i of 4.1 nM. NIDA-41020 was designed as a potential radioligand for use in positron emission tomography (PET) ^[1].

HY-110016

Docosatetraenylethanolamide DEA	Endogenous Metabolite Cannabinoid Receptor	Neurological Disease
Docosatetraenylethanolamide (DEA) is a **cannabinoid receptor 1 (CB1)** agonist. Docosatetraenylethanolamide inhibits the specific binding of cannabinoid probe to rat synaptosomal membranes with a K_i value of 34.4 nM. Docosatetraenylethanolamide can be used in the research of nervous system ^[1] .

HY-157312

TM38837	Cannabinoid Receptor	Metabolic Disease
TM38837 is an orally active and selective inverse agonist of cannabinoid receptor 1 (CB1) with an IC₅₀ of 24 nM. TM38837 has higher selectivity for CB1 than for CB2 (IC₅₀: 4500 nM). TM38837 can reduce body weight, improve plasma inflammatory markers and glucose homeostasis ^[1].

HY-116710

3-Decyl-5,5'-diphenyl-2-thioxo-4-imidazolidinone	FAAH	Others
3-Decyl-5,5'-diphenyl-2-thioxo-4-imidazolidinone (compound 45) is a potential inhibitor of fatty acid amide hydrolase (FAAH) (pI50: 5.89) and is active against CB(1) and CB(2) ) Lack of affinity for cannabinoid receptors .

HY-W775346

Delta8-THC acetate Δ8-THC acetate; Delta8-tetrahydrocannabinol	Cannabinoid Receptor	Neurological Disease Inflammation/Immunology
Delta8-THC acetate (Delta8-tetrahydrocannabinol) is a psychoactive phytocannabinoid, that binds to *cannabinoid receptor 1* (CB1 receptor), and exhibits anti-nausea, appetite-stimulating, and anti-inflammatory activities. Delta8-THC acetate exhibits probably neuroprotective efficacy and can be used in anti-anxiety and antidepressant research ^[1].

HY-172409

CB1R antagonist 2	Cannabinoid Receptor p38 MAPK NF-κB	Inflammation/Immunology
CB1R antagonist 2 (Compound 11g) is the antagonist for *cannabinoid receptor 1* (CB1R), that inhibits MAPK/NF-κB signaling pathway and exhibits anti-inflammatory activity. CB1R antagonist 2 inhibits LPS (HY-D1056)-induced IL-6, IL-1β and TNF-α expressions in RAW264.7. CB1R antagonist 2 ameliorates OVA-induced allergic rhinitis in mouse models ^[1].

HY-179885

Oleoylsulfamide	Biochemical Assay Reagents
Oleoylsulfamide is a cannabinoid receptor 1 inhibitor.

HY-179436

9β,10β-epoxy Hexahydrocannabinol 9β,10β-EHHC; 9β,10β-epoxy HHC	Cannabinoid Receptor	Neurological Disease
9β,10β-epoxy Hexahydrocannabinol is a **cannabinoid receptor 1 (CB1)** and CB2 receptor ligand with a binding affinity of 224 nM for CB1 and 335 nM for CB2. 9β,10β-epoxy Hexahydrocannabinol reduces locomotor activity, induces catalepsy, lowers body temperature, and produces antinociceptive effects in mice. 9β,10β-epoxy Hexahydrocannabinol can be used for the study of nervous system diseases ^[1].

Docosatetraenylethanolamide DEA	Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Endogenous Metabolite Cannabinoid Receptor
Docosatetraenylethanolamide (DEA) is a **cannabinoid receptor 1 (CB1)** agonist. Docosatetraenylethanolamide inhibits the specific binding of cannabinoid probe to rat synaptosomal membranes with a K_i value of 34.4 nM. Docosatetraenylethanolamide can be used in the research of nervous system ^[1] .

Species:	Human (2)
Tag:	His (1) Tag Free (1)
Source:	HEK293 (2)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P704544

	CNR1 Protein-VLP, Human (T210A, HEK293) cannabinoid receptor 1 (brain); CNR; cannabinoid receptor 1; CANN6; CB R; CB1; CB1A; CB1K5; central cannabinoid receptor; CB-R; CB1R;	Human	HEK293
	CNR1 Protein-VLP, Human (T210A, HEK293) is recommended for animal immunization, ELISA. It is not recommended for receptor-ligand interaction detection and SPR/BLI assay since there are other irrelevant membrane proteins of the host on the VLP envelope, and the receptor-ligand interaction will have strong background interference. High requirements for chips and experimental protocols are needed for SPR/BLI assays. If VLP control is required, it is recommended HY-P705433.

HY-P700408

	CNR1 Protein-VLP, Human (HEK293, His) cannabinoid receptor 1 (brain); CNR; cannabinoid receptor 1; CANN6; CB R; CB1; CB1A; CB1K5; central cannabinoid receptor; CB-R; CB1R;	Human	HEK293
	CNR1 Protein-VLP, Human (HEK293, His) is recommended for animal immunization, ELISA. It is not recommended for receptor-ligand interaction detection and SPR/BLI assay since there are other irrelevant membrane proteins of the host on the VLP envelope, and the receptor-ligand interaction will have strong background interference. High requirements for chips and experimental protocols are needed for SPR/BLI assays. If VLP control is required, it is recommended HY-P701236. Tags can only be detected under denaturing conditions.

Compare Products


Products	In-stock - + Add to Cart
Cat. No.
Species
Source
Tag
Accession
Gene ID
Molecular Weight
Purity
Endotoxin Level
Biological Activity
Appearance
Formulation
Storage & Stability
Shipping
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Host:	Rabbit (4)
Reactivity:	Human (4) Mouse (1) Rat (2)
Application:	IHC-P (2) ICC/IF (1) IHC-F (1) WB (4) ELISA (1)
Isotype:	IgG (4)
Conjugation:	Non-conjugated (4)
Clonality:	Polyclonal (1) Monoclonal (2) Recombinant (2)
Modification:	Phosphorylated (1) Unmodified (1)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P82605

	*Phospho-Cannabinoid Receptor* I (Ser316) Antibody (YA2350)** CNR1; CNR; Cannabinoid receptor 1; CB-R; CB1; CANN6	WB	Human
	Phospho-Cannabinoid Receptor I (Ser316) Antibody (YA2350) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-Cannabinoid Receptor I (Ser316).

HY-P82605A

	*Phospho-Cannabinoid Receptor* I (Ser316) Antibody (YA2350)(PBS only)** CNR1; CNR; Cannabinoid receptor 1; CB-R; CB1; CANN6	WB	Human
	Phospho-Cannabinoid Receptor I (Ser316) Antibody (YA2350) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-Cannabinoid Receptor I (Ser316).

HY-P81627

	Cannabinoid Receptor I Antibody CNR1; CNR; Cannabinoid receptor 1; CB-R; CB1; CANN6	WB, IHC-P, IHC-F, ICC/IF, ELISA	Human, Rat
	Cannabinoid Receptor I Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to Cannabinoid Receptor I.

HY-P89397

	Cannabinoid Receptor I Antibody (YA8850) CNR1; CNR; Cannabinoid receptor 1; CB-R; CB1; CANN6; CB1R antibody	WB, IHC-P	Human, Mouse, Rat
	Cannabinoid Receptor I Antibody is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Cannabinoid Receptor I.

Compare Products


Products	In-stock - + Add to Cart
Cat. No.
Host
Reactivity
Application
Dilution Ratio
Molecular Weight
Conjugation
Clonality
Immunogen
Appearance
Isotype
Gene ID
SwissProt ID
Purity
Formulation
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

Name
Email *

	Sorry, but the email address you supplied was invalid.

Cannabinoid+Receptor+1

Inhibitors & Agonists

NaturalProducts

Recombinant Proteins

Antibodies

Natural
Products