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製品番号: HY-121545

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CB-52

Name: CB-52
Brand: MedChemExpress
SKU: HY-121545
Price: 70.00 USD
Availability: InStock
Rating: 5 (1 reviews)

CB-52 is the ligand and neutral antagonist of CB2 cannabinoid receptor.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 869376-90-9
分子式: C₂₆H₄₃NO₃
分子量:417.62

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (263 KB)

CB-52 構造式

CAS 番号: 869376-90-9

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性
- 製品説明
- Cellular Effect
- 体外実験
- 体内実験
化学情報
純度とドキュメンテーション
参考文献
Calculators
Help & FAQs
関連分類
Bioz

生物活性

製品説明

CB-52 is the ligand and neutral antagonist of CB2 cannabinoid receptor^[1].

Cannabinoid Receptor アイソフォーム固有の製品をすべて表示 :

Cellular Effect

Cell Line	Type	Value	Description	References
RBL-2H3	IC₅₀	13 μM Compound: 52	Inhibition of anandamide membrane transporter in RBL-2H3 cells assessed as [14C]anandamide uptake Inhibition of anandamide membrane transporter in RBL-2H3 cells assessed as [14C]anandamide uptake	[PMID: 16279794]

体外実験

CB-52 inhibits Forskolin (HY-15371)-induced cAMP formation by N18TG2 cells (IC₅₀: 450 nM) and hCB1-CHO cells (EC₅₀: 2600 nM)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .

体内実験

CB-52 (1 and 5 mg/kg, i.p.) decreases pain threshold to thermal stimulation in rats, and blocks WIN55,212-2 (2.5 mg/kg, i.p.) caused anti-nociceptive effect^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

CAS 番号 869376-90-9
分子量 417.62
分子式 C₂₆H₄₃NO₃
SMILES

O=C(CCCCCCCCCCOC1=CC(O)=CC=C1CCCCCC)NC2CC2
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (263 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Cascio MG, et al. In vitro and in vivo pharmacology of synthetic olivetol- or resorcinol-derived cannabinoid receptor ligands. Br J Pharmacol. 2006 Oct;149(4):431-40. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

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100 mg

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