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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
31 Results for "
DMG-PEG2000
" in MedChemExpress (MCE) Product Catalog:
Products (31)
31 Results for "DMG-PEG2000" in MCE Product Catalog:
Cat. No.: HY-167036
CAS No.: 3101670-33-8
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DMG-PEG2000-Mal is a pegylated lipid with a molecular weight of 2000. DMG-PEG-Mal serves as a component of lipid nanoparticles for mRNA delivery .
Cat. No.: HY-174264
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DMG-PEG2000-NHS is a polyethylene glycol lipid with a molecular weight of 2000, which can be used to construct novel drug delivery systems that confer mucoadhesive and cell-targeting capabilities to lipid nanoparticles .
Cat. No.: HY-P10392AF
Cat. No.: HY-P10896
CAS No.: 1446005-10-2
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Cat. No.: HY-W1123934A
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DMG-PEG2000-SH is a PEG derivative that can be used to construct drug delivery vehicles.
Cat. No.: HY-W1123940A
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DMG-PEG2000-OH is a pegylated lipid. DMG-PEG2000-OH features a hydrophobic dimyristoyl glycerol anchor (C14 chains) attached to a hydrophilic polyethylene glycol chain (MW 2000). DMG-PEG2000-OH is widely used as an excipient to formulate lipid nanoparticles (LNPs) and liposomes for drug and RNA delivery.
Cat. No.: HY-169232
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Cat. No.: HY-187246A
Synonyms: DMG-PEG2000-CSRNLIDC
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DMG-PEG2000-pPB (DMG-PEG2000-CSRNLIDC) is a functionalized PEGylated lipid conjugate composed of three modular components: dimyristoylglycerol (DMG) as the lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 2000 Da, and platelet-derived growth factor receptor β-binding peptide (pPB peptide (HY-P11549)) as the terminal targeting/functional ligand. DMG-PEG2000-pPB enables targeted delivery to fibrotic tissues and tumor stroma.
Cat. No.: HY-182903A
DMG-PEG2000-Mannose is a conjugate composed of dimyristoylglycerol (DMG), a PEG chain, and terminal mannose. DMG-PEG2000-Mannose combines the membrane compatibility of phospholipids with the targeted recognition capabilities of mannose, making it suitable for research in biomaterial construction and drug delivery.
Cat. No.: HY-187241A
Synonyms: DMG-PEG2000-APWHLSSQYSRT
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DMG-PEG2000-CTP is a functionalized PEGylated lipid conjugate composed of three modular components: dimyristoylglycerol (DMG) as the lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 2000 Da, and CTP (cardiotropic targeting peptide) (HY-P4094) as the terminal targeting/functional ligand. DMG-PEG2000-CTP can be incorporated into liposomes, lipid nanoparticles (LNPs), or other nanocarriers, conferring cardiac targeting capability.
Cat. No.: HY-183196A
DMG-PEG2000-Galactose is a conjugate composed of dimyristic glycerol (DMG), a PEG chain, and terminal galactose. DMG-PEG2000-Galactose combines the membrane compatibility of phospholipids with the targeted recognition capabilities of galactose, making it suitable for research in biomaterial construction and drug delivery.
Cat. No.: HY-183398A
DMG-PEG2000-CHO is a conjugate composed of dimyristic glycerol (DMG), a PEG chain, and a terminal aldehyde group (-CHO). DMG-PEG2000-CHO combines the membrane compatibility of phospholipids with the flexibility of hydroxyl modification, making it suitable for research in biomaterial construction and drug delivery.
Cat. No.: HY-200288
DMG-PEG2000-COOH is a conjugate composed of DMG, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DMG-PEG2000-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.
Cat. No.: HY-183191A
DMG-PEG2000-Alkyne is a conjugate composed of dimyristic glycerol (DMG), a PEG chain, and a terminal alkyne group. DMG-PEG2000-Alkyne combines the membrane compatibility of phospholipids with the high reactivity of the alkyne group in click chemistry, making it suitable for research in biomaterial construction and drug delivery.
Cat. No.: HY-183156A
DMG-PEG2000-Glucose is a conjugate composed of dimyristic glycerol (DMG), a PEG chain, and terminal glucose. DMG-PEG2000-Glucose combines the membrane compatibility of phospholipids with glucose as an active site for sugar recognition or subsequent coupling reactions, making it suitable for research in biomaterial construction and drug delivery.
Cat. No.: HY-187243A
Synonyms: DMG-PEG2000-Cys-SRNLIDC
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DMG-PEG2000-LyP-1 (DMG-PEG2000-Cys-SRNLIDC) is a functionalized PEGylated lipid conjugate composed of three modular components: dimyristoylglycerol (DMG) as the lipid anchoring group, PEG, and LyP-1 peptide (CGNKRTRGC) (HY-P2526) as the terminal targeting/functional ligand. LyP-1 is a cyclic 9-amino acid peptide that specifically binds to p32/gC1qR protein, which is highly expressed on tumor-associated macrophages, lymphatic endothelial cells, and certain tumor cells. DMG-PEG2000-LyP-1 can be incorporated into liposomes, lipid nanoparticles (LNPs), or other nanocarriers to confer ligand-directed targeting capability against p32/gC1qR protein on the surface of lymphatic vessels, tumor-associated macrophages, and tumor cells.
Cat. No.: HY-187327A
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DMG-PEG2000-TAT is a functionalized PEGylated lipid conjugate composed of three modular components: dimyristoylglycerol (DMG) as the lipid anchoring groupPEG, and TAT peptide (YGRKKRRQRRR) (HY-P0281) as the terminal targeting/functional ligand. DMG-PEG2000-TAT can be incorporated into liposomes, lipid nanoparticles (LNPs), or other nanocarriers to confer ligand-directed targeting capability against non-specific cell membrane penetration (heparan sulfate proteoglycans).
Cat. No.: HY-184572A
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DMG-PEG2000-WYRGRL is a functionalized PEGylated lipid conjugate composed of three modular components: dimyristoylglycerol (DMG) as the lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 2000 Da, and WYRGRL peptide (HY-P10739)as the terminal targeting/functional ligand. DMG-PEG2000-WYRGRL can be incorporated into liposomes, lipid nanoparticles (LNPs), or other nanocarriers to confer ligand-directed targeting capability against specific cell surface receptors in tumor and inflammatory microenvironments.
Cat. No.: HY-186175
DMG-PEG2000-Mal-Cys-penetratin is a conjugate composed of dimyristoylglycerol (DMG), a PEG chain, and terminal maleimide (Mal). DMG-PEG2000-Mal-Cys-penetratin combines the membrane compatibility of lipids, the specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers) by maleimide, and cell-penetrating peptides, making it suitable for research on biomaterial construction and drug delivery to cells.
Cat. No.: HY-184577A
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DMG-PEG2000-iRGD is a functionalized PEGylated lipid conjugate composed of three modular components: dimyristoylglycerol (DMG) as the lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 2000 Da, and iRGD peptide (HY-P0122) as the terminal targeting/functional ligand. DMG-PEG2000-iRGD can be incorporated into liposomes, lipid nanoparticles (LNPs), or other nanocarriers to confer ligand-directed targeting capability against sequential binding to αv integrins on tumor vasculature → neuropilin-1 (NRP1) in tumor tissue.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
