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Factor VIII

" in MedChemExpress (MCE) Product Catalog:

標的別:	Factor VIII (7) Factor Xa (2)
研究分野別:	Cardiovascular Disease (8) Inflammation/Immunology (1) Metabolic Disease (1)

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Targets Recommended: Factor VIII

製品番号	製品名	Target	研究分野	構造式

HY-P9940

Emicizumab ACE-910; RG6013	Factor VIII	Cardiovascular Disease
Emicizumab is a bispecific monoclonal antibody that bridges activated factor IX and factor X to replace the function of missing activated factor VIII, thereby restoring hemostasis. Emicizumab can be used for hemophilia A research .

HY-P990060

Denecimig Mim8	Factor Xa	Cardiovascular Disease
Denecimig (Mim8) is a factor VIII-mimetic bispecific antibody with micromolar human binding affinity for Factor X and Factor IXa. Denecimig binds Factor X and Factor IXa, localizes both to the phospholipid surface, enhances the Factor IXa-mediated activation of Factor X to Factor Xa, and stimulates the proteolytic activity of Factor IXa via its monovalent anti-Factor IXa arm. Denecimig is applicable to research related to hemophilia A .

HY-112998

Efmoroctocog alfa	Factor VIII	Cardiovascular Disease
Efmoroctocog alfa is a recombinant factor *VIII-Fc* fusion protein (rFVIIIFc). In mice with hemophilia A, Efmoroctocog alfa provides longer-lasting protection against tail vein transection injury than conventional rFVIII products. In dogs with hemophilia A, Efmoroctocog alfa produces a longer duration of improvement in whole blood clotting time than conventional rFVIII products. Efmoroctocog alfa can be used for research on hemophilia A .

HY-P2008

Boc-Ile-Glu-Gly-Arg-AMC 1 Publications Verification IEGR-AMC	Factor Xa	Cardiovascular Disease
Boc-Ile-Glu-Gly-Arg-AMC (IEGR-AMC) is an activated factor X (FXa) specific fluorogenic peptide substrate used for Factor VIII determination .

HY-112865

Octocog alfa ADVATE; BAY 81-8973; Kovaltry	Factor VIII	Cardiovascular Disease
Octocog alfa (ADVATE; BAY 81-8973; Kovaltry) is a standard half-length recombinant coagulation factor FVIII replacement therapy that also functions as a thrombin generation modulator. Octocog alfa regulates thrombin generation-related parameters in vitro and is used in studies related to severe hemophilia A .

HY-114128

Turoctocog alfa pegol NN-7088; NN 7170	Factor VIII	Others
Turoctocog alfa pegol is a recombinant *coagulation factor* VIII (FVIII)** from chinese hamster ovary (CHO) cells. Turoctocog alfa pegol can be used for researching haemophilia A .

HY-P99769

Omfiloctocog alfa SCT-800	Factor VIII	Metabolic Disease
Omfiloctocog alfa (SCT-800) is a recombinant factor VIII (FVIII). FVIII is an essential blood coagulation protein and a key component of the fluid phase blood coagulation system. Omfiloctocog alfa can be used for the research of Hemophilia A .

HY-P991516

TB-402	Factor VIII	Cardiovascular Disease
TB-402, a human IgG4 anticoagulant monoclonal antibody, is a partial **Factor VIII** inhibitor. TB-402 has a prolonged antithrombotic effect. TB-402 can be used for the prevention of venous thromboembolism (VTE) after total knee replacement (TKR) .

HY-P9940A

Emicizumab (Anti-F9 & Factor IX)	Factor VIII	Cardiovascular Disease
Emicizumab (Anti-F9 & Factor IX) is a bispecific monoclonal antibody that bridges activated factor IX and factor X to replace the function of missing activated factor VIII, thereby restoring hemostasis. Emicizumab (Anti-F9 & Factor IX) can be used for hemophilia A research .

製品番号	製品名	Target	研究分野

HY-P2008

Boc-Ile-Glu-Gly-Arg-AMC 1 Publications Verification IEGR-AMC	Factor Xa	Cardiovascular Disease
Boc-Ile-Glu-Gly-Arg-AMC (IEGR-AMC) is an activated factor X (FXa) specific fluorogenic peptide substrate used for Factor VIII determination .

製品番号	製品名	Target	研究分野	Image

HY-P9940

Emicizumab ACE-910; RG6013	Factor VIII	Cardiovascular Disease
Emicizumab is a bispecific monoclonal antibody that bridges activated factor IX and factor X to replace the function of missing activated factor VIII, thereby restoring hemostasis. Emicizumab can be used for hemophilia A research .

HY-P990060

Denecimig Mim8	Factor Xa	Cardiovascular Disease
Denecimig (Mim8) is a factor VIII-mimetic bispecific antibody with micromolar human binding affinity for Factor X and Factor IXa. Denecimig binds Factor X and Factor IXa, localizes both to the phospholipid surface, enhances the Factor IXa-mediated activation of Factor X to Factor Xa, and stimulates the proteolytic activity of Factor IXa via its monovalent anti-Factor IXa arm. Denecimig is applicable to research related to hemophilia A .

HY-112998

Efmoroctocog alfa	Factor VIII	Cardiovascular Disease
Efmoroctocog alfa is a recombinant factor *VIII-Fc* fusion protein (rFVIIIFc). In mice with hemophilia A, Efmoroctocog alfa provides longer-lasting protection against tail vein transection injury than conventional rFVIII products. In dogs with hemophilia A, Efmoroctocog alfa produces a longer duration of improvement in whole blood clotting time than conventional rFVIII products. Efmoroctocog alfa can be used for research on hemophilia A .

HY-P99875

Efanesoctocog alfa BIVV-001; Altuvoct	阻害性抗体	Cardiovascular Disease
Efanesoctocog alfa is a B domain-deleted single-chain Factor VIII (FVIII) connected to D'D3 domain of von Willebrand Factor (vWF). Efanesoctocog alfa has an extended half-life. Efanesoctocog alfa can be used for the study of inherited hemophilia A .

HY-114128

Turoctocog alfa pegol NN-7088; NN 7170	Factor VIII	Others
Turoctocog alfa pegol is a recombinant *coagulation factor* VIII (FVIII)** from chinese hamster ovary (CHO) cells. Turoctocog alfa pegol can be used for researching haemophilia A .

HY-P99769

Omfiloctocog alfa SCT-800	Factor VIII	Metabolic Disease
Omfiloctocog alfa (SCT-800) is a recombinant factor VIII (FVIII). FVIII is an essential blood coagulation protein and a key component of the fluid phase blood coagulation system. Omfiloctocog alfa can be used for the research of Hemophilia A .

HY-P990412

*Anti-F8/Factor* VIII Antibody**	阻害性抗体	Inflammation/Immunology
Anti-F8/Factor VIII Antibody is a CHO-expressed human antibody that targets F8/Factor VIII. Anti-F8/Factor VIII Antibody has a huIgG4 type heavy chain and a huκ type light chain, with a predicted molecular weight (MW) of 150 kDa. The isotype control for Anti-F8/Factor VIII Antibody can refer to Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P991516

TB-402	Factor VIII	Cardiovascular Disease
TB-402, a human IgG4 anticoagulant monoclonal antibody, is a partial **Factor VIII** inhibitor. TB-402 has a prolonged antithrombotic effect. TB-402 can be used for the prevention of venous thromboembolism (VTE) after total knee replacement (TKR) .

HY-P9940A

Emicizumab (Anti-F9 & Factor IX)	Factor VIII	Cardiovascular Disease
Emicizumab (Anti-F9 & Factor IX) is a bispecific monoclonal antibody that bridges activated factor IX and factor X to replace the function of missing activated factor VIII, thereby restoring hemostasis. Emicizumab (Anti-F9 & Factor IX) can be used for hemophilia A research .

Species:	Human (3)
Tag:	His (2) Fc (1)
Source:	HEK293 (3)

製品番号	Compare	製品名	Species	Source	Image

HY-P70189

	EGFR vIII Protein, Human (HEK293, His) rHuEpidermal Growth Factor Receptor/EGFR VIII, His; Epidermal growth Factor receptor; EGFR; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1; EGFR	Human	HEK293
	The EGFRvIII protein is a transmembrane glycoprotein in the protein kinase superfamily that acts as a receptor for epidermal growth factor. It acts on the cell surface, binds to epidermal growth factor, triggers receptor dimerization and tyrosine autophosphorylation, and promotes cell proliferation. EGFR vIII Protein, Human (HEK293, His) is the recombinant human-derived EGFR vIII protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P70608

	EGFR vIII Protein, Human (HEK293, Fc) 1 Publications Verification Epidermal growth Factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1; EGFR; ERBB; ERBB1; HER1	Human	HEK293
	The EGFR vIII protein is a transmembrane glycoprotein in the protein kinase superfamily that acts as a receptor for epidermal growth factor. It acts on the cell surface, binds to epidermal growth factor, triggers receptor dimerization and tyrosine autophosphorylation, and promotes cell proliferation. EGFR vIII Protein, Human (HEK293, Fc) is the recombinant human-derived EGFR vIII protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P70095

	DCBLD2 Protein, Human (HEK293, His) rHuDiscoidin, CUB and LCCL domain-containing protein 2/ DCBLD2, His; Discoidin; CUB and LCCL domain-containing protein 2; DCBLD2; CUB; LCCL and coagulation Factor V/VIII-homology domains protein 1; Endothelial and smooth muscle cell-derived neuropilin-like protein; DCBLD2; CLCP1; ESDN;	Human	HEK293
	DCBLD2 Protein is a novel platelet membrane receptor that recruits TRAF6 through EGFR phosphorylation and stimulates AKT to promote tumorigenesis. The DCBLD2 Protein has multiple functions during development as well as in vascular and tumor biology, such as influencing cell proliferation and tumorigenesis. DCBLD2 Protein, Human (HEK293, His) is the recombinant human-derived DCBLD2 protein, expressed by HEK293 , with C-6*His labeled tag.

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HY-P85156

	Factor VIII Antibody F8; F8C; Coagulation Factor VIII; Antihemophilic Factor; AHF; Procoagulant component	WB, IHC-P, ICC/IF, ELISA	Human, Mouse
	Factor VIII Antibody (YA4848) is a Rabbit-derived and non-conjugated monoclonal antibody, targeting to Factor VIII.

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