2. Metabolic Enzyme/Protease
  3. Factor VIII
  4. Efmoroctocog alfa

Efmoroctocog alfa is a recombinant factor VIII-Fc fusion protein (rFVIIIFc). In mice with hemophilia A, Efmoroctocog alfa provides longer-lasting protection against tail vein transection injury than conventional rFVIII products. In dogs with hemophilia A, Efmoroctocog alfa produces a longer duration of improvement in whole blood clotting time than conventional rFVIII products. Efmoroctocog alfa can be used for research on hemophilia A.

For research use only. We do not sell to patients.

CAS No. : 1270012-79-7

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250 IU In-stock

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Efmoroctocog alfa Related Antibodies

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Description

Efmoroctocog alfa is a recombinant factor VIII-Fc fusion protein (rFVIIIFc). In mice with hemophilia A, Efmoroctocog alfa provides longer-lasting protection against tail vein transection injury than conventional rFVIII products. In dogs with hemophilia A, Efmoroctocog alfa produces a longer duration of improvement in whole blood clotting time than conventional rFVIII products. Efmoroctocog alfa can be used for research on hemophilia A[1].

In Vivo

Efmoroctocog alfa provides hemostatic protection against tail vein transection injury in hemophilia A mice that is 1.5 to 2 times longer than that provided by conventional rFVIII products[1].
Efmoroctocog alfa improves the whole blood clotting time in dogs with hemophilia A for 1.5 to 2 times longer than conventional rFVIII products[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
Application

ELISA, FACS, Functional assay
Conjugated

Unconjugated
Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.
Molecular Weight

220 kDa

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

[Efmoroctocog alfa]
Formulation

Please refer to the lot-specific COA for specific buffer information.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • [F8 (coagulation factor VIII)recombinant]1-IGHG1 Fc (Fragment constant)
Purity & Documentation
References
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Efmoroctocog alfa Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Efmoroctocog alfa1270012-79-7Factor VIIICoagulation factor VIIIFVIIIacute bleeding episodeshalf-life extenderhaemophilia Ahaemophilia A dogsrecombinant factor VIII-Fc fusion proteinwhole blood clotting timehaemophilia A miceperioperative haemostasishaemostatic agentInhibitorinhibitorinhibit

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