Efmoroctocog alfa
Based on 1 Customer Validation
Efmoroctocog alfa is a recombinant factor VIII-Fc fusion protein (rFVIIIFc). In mice with hemophilia A, Efmoroctocog alfa provides longer-lasting protection against tail vein transection injury than conventional rFVIII products. In dogs with hemophilia A, Efmoroctocog alfa produces a longer duration of improvement in whole blood clotting time than conventional rFVIII products. Efmoroctocog alfa can be used for research on hemophilia A.
For research use only. We do not sell to patients.
- Purity: 95%
- CAS No.: 1270012-79-7
- Molecular Weight:220 kDa
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Fusion-[F8 (coagulation factor VIII)]1-IGHG1 Fc
Efmoroctocog alfa improves the whole blood clotting time in dogs with hemophilia A for 1.5 to 2 times longer than conventional rFVIII products[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
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[F8 (coagulation factor VIII)recombinant]1-IGHG1 Fc (Fragment constant)
Chemical Information
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CAS No. 1270012-79-7
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Appearance Solid
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Molecular Weight 220 kDa
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Color White to off-white
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SMILES
[Efmoroctocog alfa]
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Synonyms
BIIB-031
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (255 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)