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Fructose-1,6-bisphosphate

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Fructose-1,6-bisphosphate aldolase (3) Biochemical Assay Reagents (3) Endogenous Metabolite (2) Fungal (1) Phosphatase (2)
By Research Areas:	Infection (1) Metabolic Disease (4)

Inhibitors & Agonists

Biochemical Assay Reagents

Recombinant Proteins

Antibodies

Targets Recommended: Fructose-1,6-bisphosphate aldolase

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P2726

Aldolase, Rabbit muscle Fructose-diphosphate aldolase	Fructose-1,6-bisphosphate aldolase Endogenous Metabolite	Metabolic Disease
Aldolase, Rabbit muscle (Fructose-diphosphate aldolase) is a glycolytic enzyme and glucose availability sensor. Aldolase, Rabbit muscle catalyzes the reversible carbon-carbon cleavage of fructose-1,6-bisphosphate to produce dihydroxyacetone phosphate and glyceraldehyde 3-phosphate. Aldolase, Rabbit muscle is an essential component for v-ATPase activity. Aldolase, Rabbit muscle participates in processes such as gluconeogenesis, the Calvin cycle and glycolysis .

HY-W134005

Mg(Ⅱ)-EDTA disodium tetrahydrate Ethylenediaminetetraacetic acid magnesium disodium tetrahydrate	Phosphatase	Others
Mg(Ⅱ)-EDTA disodium tetrahydrate is a reversible non-covalent activator of fructose diphosphatase (K_m=0.9 μM). Mg(Ⅱ)-EDTA disodium tetrahydrate synergistically activates fructose diphosphatase with free Mg ²⁺, promotes the hydrolysis of fructose-1,6-bisphosphate at pH≤8, and plays a role in enhancing the activity of key enzymes in gluconeogenesis .

HY-143899

FBA-IN-1	Fructose-1,6-bisphosphate aldolase Fungal	Infection
FBA-IN-1 (compound 2a11) is a first-in-class, covalent and allosteric inhibitor of fructose-1,6-bisphosphate aldolase from Candida albicans (CaFBA). FBA-IN-1 inhibits the growth of Azole-resistant strains 103 with the MIC₈₀ of 1 μg/mL .

HY-P2819

Phosphofructokinase 1 PFK1	Phosphatase	Metabolic Disease
Phosphofructokinase 1 (PFK1) is a major regulatory enzyme targeting glycolytic pathway. Phosphofructokinase 1 catalyzes the phosphorylation of fructose-6-phosphate (F6P) to fructose-1,6-bisphosphate (F1,6BP) to regulate glycolytic flux. Phosphofructokinase 1 is promising for research of cancer metabolic reprogramming (e.g., hypoxia adaptation, oxidative stress resistance) and metabolic syndromes .

HY-106950B

*D-Fructose 1,6-bisphosphate* tetracyclohexylammonium**	Biochemical Assay Reagents	Others
D-Fructose 1,6-bisphosphate (tetracyclohexylammonium) is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .

HY-E71030

Aldolase A, Human	Biochemical Assay Reagents Fructose-1,6-bisphosphate aldolase	Others
Aldolase A, Human (EC 4.1.2.13) is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Aldolase A, Human (EC 4.1.2.13) , fused to His-tag at N-terminus, was expressed in E.coli.

HY-E70994

Fructose-6-phosphate Kinase, Bacillus stearothermophilus	Biochemical Assay Reagents	Metabolic Disease
Fructose-6-phosphate Kinase, Bacillus stearothermophilus (EC 2.7.1.11) is an important enzyme in glucose metabolism. Fructose-6-phosphate Kinase, Bacillus stearothermophilus (EC 2.7.1.11) catalyzes the hydrolysis of fructose-1,6-bisphosphate to fructose-6-phosphate and inorganic phosphate.

HY-P2819A

Phosphofructokinase,Bacillus stearothermophilus	Endogenous Metabolite	Metabolic Disease
Phosphofructokinase from Bacillus stearothermophilus is a key enzyme in sugar metabolism that catalyzes the conversion of fructose-6-phosphate to fructose-1,6-bisphosphate during glycolysis. The enzyme's ability to bind fructose-6-phosphate can be inhibited by phosphoenolpyruvate (PEP), thereby regulating the rate of glycolysis. Phosphofructokinase from Bacillus stearothermophilus can be used for the measurement of fructose-6-phosphate levels .

Cat. No.	Product Name	Type

HY-W134005

Mg(Ⅱ)-EDTA disodium tetrahydrate Ethylenediaminetetraacetic acid magnesium disodium tetrahydrate	Biochemical Assay Reagents
Mg(Ⅱ)-EDTA disodium tetrahydrate is a reversible non-covalent activator of fructose diphosphatase (K_m=0.9 μM). Mg(Ⅱ)-EDTA disodium tetrahydrate synergistically activates fructose diphosphatase with free Mg ²⁺, promotes the hydrolysis of fructose-1,6-bisphosphate at pH≤8, and plays a role in enhancing the activity of key enzymes in gluconeogenesis .

HY-106950B

*D-Fructose 1,6-bisphosphate* tetracyclohexylammonium**	Biochemical Assay Reagents
D-Fructose 1,6-bisphosphate (tetracyclohexylammonium) is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .

D-Fructose 1,6-bisphosphate tetracyclohexylammonium

Biochemical Assay Reagents

D-Fructose 1,6-bisphosphate (tetracyclohexylammonium) is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .

Species:	Human (1)
Tag:	His (2) Tag Free (1)
Source:	HEK293 (1) E. coli (2)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P701883

	fbaA Protein, Shigella flexneri fbaA; Fructose-bisphosphate aldolase class 2; FBP aldolase; FBPA; Fructose-1; 6-bisphosphate aldolase; Fructose-bisphosphate aldolase class II	Others	E. coli
	The fbaA protein plays a critical role in cellular metabolism by catalyzing the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerol phosphate) with glyceraldehyde 3-phosphate (G3P), leading to the formation of fructose 1,6-bisphosphate (FBP) role. This enzyme activity is essential for gluconeogenesis and glycolysis, reflecting its involvement in the conversion of key intermediates necessary for energy production and carbon flux. fbaA Protein, Shigella flexneri is the recombinant fbaA protein, expressed by E. coli , with tag free.

HY-P701884

	fbaA Protein, Shigella flexneri (His) fbaA; Fructose-bisphosphate aldolase class 2; FBP aldolase; FBPA; Fructose-1; 6-bisphosphate aldolase; Fructose-bisphosphate aldolase class II	Others	E. coli
	The fbaA protein plays a critical role in cellular metabolism by catalyzing the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerol phosphate) with glyceraldehyde 3-phosphate (G3P), leading to the formation of fructose 1,6-bisphosphate (FBP) role. This enzyme activity is essential for gluconeogenesis and glycolysis, reflecting its involvement in the conversion of key intermediates necessary for energy production and carbon flux. fbaA Protein, Shigella flexneri (His) is the recombinant fbaA protein, expressed by E. coli , with N-6*His labeled tag.

HY-P70275

	FBP1 Protein, Human (HEK293, His) 2 Publications Verification rHuFructose-1,6-bisphosphatase 1/FBP1, His; Fructose-1; 6-bisphosphatase 1; D-Fructose-1; 6-bisphosphate 1-phosphohydrolase 1; FBP; FBPase 1	Human	HEK293
	The FBP1 protein plays a crucial role in cellular processes by catalyzing the hydrolysis of fructose-1,6-bisphosphate to fructose-6-phosphate, acting as a rate-limiting enzyme in gluconeogenesis. In addition to playing a key role in glucose metabolism, FBP1 also plays an important role in regulating glucose sensing and insulin secretion in pancreatic β cells. FBP1 Protein, Human (HEK293, His) is the recombinant human-derived FBP1 protein, expressed by HEK293 , with C-6*His labeled tag.

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HY-P81519

	FBP1 Antibody (YA1264) 6-bisphosphatase 1 antibody; 6-bisphosphate 1-phosphohydrolase 1 antibody; D Fructose 1 6 bisphosphate 1 phosphohydrolase 1 antibody; D-Fructose-1 antibody; EC 3.1.3.11 antibody; F16P1_HUMAN antibody; FBP antibody; FBP 1 antibody; FBP1 antibody; FBPase 1 antibody; Fructose 1 6 bisphosphatase 1 antibody; Fructose bisphosphatase 1 antibody; Fructose-1 antibody; Growth inhibiting protein 17 antibody; Liver Fructose bisphosphatase antibody;	WB, IHC-P, ICC/IF	Human, Mouse, Rat
	FBP1 Antibody (YA1264) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to FBP1.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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