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Group I metabotropic glutamate receptor

" in MedChemExpress (MCE) Product Catalog:
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製品番号 製品名 Target 研究分野 構造式
  • HY-12598
    (S)-3,5-DHPG

    		mGluR Neurological Disease
    (S)-3,5-DHPG is a weak, but selective group I metabotropic glutamate receptors (mGluRs) agonist with Ki values of 0.9 μM and 3.9 μM for mGluR1a and mGluR5a, respectively . (S)-3,5-DHPG exhibits anxiolytic activity in rats subjected to hypoxia .
    (S)-3,5-DHPG
  • HY-100371
    (RS)-MCPG
    1 Publications Verification

    alpha-MCPG

    		 mGluR Neurological Disease
    (RS)-MCPG (alpha-MCPG) is a competitive and selective group I/group II metabotropic glutamate receptor (mGluR) antagonist. (RS)-MCPG blocks theta-burst stimulation (TBS)-induced shifts in both juvenile and neonatal rat hippocampal neurons .
    (RS)-MCPG
  • HY-100406
    (S)-MCPG
    1 Publications Verification

    (+)-MCPG

    		 mGluR Neurological Disease
    (S)-MCPG ((+)-MCPG) is a potent group I/II metabotropic glutamate receptor (mGluRs) antagonist and the active isomer of (RS)-MCPG (HY-100371) . (S)-MCPG can be used for the study of the function of mGluRs in spatial learning .
    (S)-MCPG
  • HY-101311
    UPF-523

    AIDA

    		 mGluR Inflammation/Immunology Cancer
    UPF-523 (AIDA), a rigid (carboxyphenyl) glycine derivative, is a relatively potent and selective antagonist of group I metabotropic glutamate receptors (mGlu1a) with an IC50 of 214 μM. But UPF-523 has no effect on group II (mGlu2), group III (mGlu4) receptors or ionotropic glutamate receptors. UPF-523 has the potential for the research of the acute arthritis .
    UPF-523
  • HY-100372
    E4CPG

    (RS)-ECPG

    		 mGluR Neurological Disease
    E4CPG ((RS)-ECPG) is a Group I/Group II metabotropic glutamate receptor (mGluR) antagonist. E4CPG can inhibit the paired-pulse ratio of monosynaptic inhibitory postsynaptic currents (IPSC) potentiation .
    E4CPG
  • HY-100371R
    (RS)-MCPG (Standard)

    alpha-MCPG (Standard)

    		 Reference Standards mGluR Neurological Disease
    (RS)-MCPG (Standard) is the analytical standard of (RS)-MCPG. This product is intended for research and analytical applications. (RS)-MCPG (alpha-MCPG) is a competitive and selective group I/group II metabotropic glutamate receptor (mGluR) antagonist. (RS)-MCPG blocks theta-burst stimulation (TBS)-induced shifts in both juvenile and neonatal rat hippocampal neurons .
    (RS)-MCPG (Standard)
  • HY-100406R
    (S)-MCPG (Standard)

    (+)-MCPG (Standard)

    		 mGluR Reference Standards Neurological Disease
    (S)-MCPG (Standard) is the analytical standard of (S)-MCPG (HY-100406). This product is intended for research and analytical applications. (S)-MCPG ((+)-MCPG) is a potent group I/II metabotropic glutamate receptor (mGluRs) antagonist and the active isomer of (RS)-MCPG (HY-100371) . (S)-MCPG can be used for the study of the function of mGluRs in spatial learning .
    (S)-MCPG (Standard)
  • HY-132227
    Dichlorobenzamil hydrochloride

    3',4'-Dichlorobenzamil hydrochloride; L-594881 hydrochloride

    		 Na+/Ca2+ Exchanger Others
    Dichlorobenzamil (3',4'-Dichlorobenzamil; L-594881) hydrochloride is a Na +-Ca 2+ Exchanger inhibitor. Dichlorobenzamil (hydrochloride) attenuates the Na +-Ca 2+ exchanger-mediated inward current induced by activation of type I metabotropic glutamate receptors in second-order baroreceptor neurons of the rat nucleus tractus solitarius .
    Dichlorobenzamil hydrochloride

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