Dichlorobenzamil hydrochloride
Dichlorobenzamil (3',4'-Dichlorobenzamil; L-594881) hydrochloride is a Na+-Ca2+ Exchanger inhibitor. Dichlorobenzamil (hydrochloride) attenuates the Na+-Ca2+ exchanger-mediated inward current induced by activation of type I metabotropic glutamate receptors in second-order baroreceptor neurons of the rat nucleus tractus solitarius.
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- CAS No.: 928621-15-2
- Formula: C13H13Cl4N7O
- Molecular Weight:425.10
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Dichlorobenzamil hydrochloride (100 μM; 1 min) significantly attenuates the Group I mGluR agonist-induced inward current in anatomically identified second-order baroreceptor NTS neurons, reducing the current to 55.1 ± 8.6% of control[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 928621-15-2
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Molecular Weight 425.10
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Formula C13H13Cl4N7O
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SMILES
O=C(C1=NC(Cl)=C(N)N=C1N)NC(NCC2=CC=C(C(Cl)=C2)Cl)=N.Cl
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Synonyms
3',4'-Dichlorobenzamil hydrochloride; L-594881 hydrochloride
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Dichlorobenzamil hydrochloride Related Classifications
HY-132227 Related Classifications
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