2. Membrane Transporter/Ion Channel
  3. Na+/Ca2+ Exchanger
  4. Dichlorobenzamil hydrochloride

Dichlorobenzamil hydrochloride  (Synonyms: 3',4'-Dichlorobenzamil hydrochloride; L-594881 hydrochloride)

Cat. No.: HY-132227
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Dichlorobenzamil (3',4'-Dichlorobenzamil; L-594881) hydrochloride is a Na+-Ca2+ Exchanger inhibitor. Dichlorobenzamil (hydrochloride) attenuates the Na+-Ca2+ exchanger-mediated inward current induced by activation of type I metabotropic glutamate receptors in second-order baroreceptor neurons of the rat nucleus tractus solitarius.

For research use only. We do not sell to patients.

Dichlorobenzamil hydrochloride

Dichlorobenzamil hydrochloride Chemical Structure

CAS No. : 928621-15-2

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Other Forms of Dichlorobenzamil hydrochloride:

Dichlorobenzamil hydrochloride Related Antibodies

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Description

Dichlorobenzamil (3',4'-Dichlorobenzamil; L-594881) hydrochloride is a Na+-Ca2+ Exchanger inhibitor. Dichlorobenzamil (hydrochloride) attenuates the Na+-Ca2+ exchanger-mediated inward current induced by activation of type I metabotropic glutamate receptors in second-order baroreceptor neurons of the rat nucleus tractus solitarius[1].

In Vitro

Dichlorobenzamil hydrochloride (100 μM; 1 min) significantly attenuates the Group I mGluR agonist-induced inward current in anatomically identified second-order baroreceptor NTS neurons, reducing the current to 55.1 ± 8.6% of control[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Dichlorobenzamil hydrochloride Related Antibodies
Molecular Weight

425.10

Formula

C13H13Cl4N7O
CAS No.
SMILES

O=C(C1=NC(Cl)=C(N)N=C1N)NC(NCC2=CC=C(C(Cl)=C2)Cl)=N.Cl
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
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References
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Dichlorobenzamil hydrochloride Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Dichlorobenzamil928621-15-23',4'-DichlorobenzamilL-594881L594881L 594881Na+/Ca2+ ExchangerNTS neuronsrat nucleus tractus solitariusGroup I mGluR agonistGroup I metabotropic glutamate receptorsecond-order baroreceptor neuronsNa+-Ca2+ exchangerInhibitorinhibitorinhibit

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