Dichlorobenzamil
Dichlorobenzamil (3',4'-Dichlorobenzamil; L-594881) is an effective Na/Ca exchange inhibitor. Dichlorobenzamil significantly inhibits 45Ca uptake mediated by reverse Na/Ca exchange in pancreatic islet cells (IC50 = 18 μM). Dichlorobenzamil can also block K+ channels and voltage-sensitive Ca2+ channels.
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- CAS No.: 1166-01-4
- Formule: C13H12Cl3N7O
- Masse moléculaire:388.64
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Activité biologique
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Huh-7 | CC50 |
4.59 μM
Compound: GNF-Pf-1778
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NOVARTIS: Cytotoxicity against human hepatocellular carcinoma cell line (Huh7)
NOVARTIS: Cytotoxicity against human hepatocellular carcinoma cell line (Huh7)
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[PMID: 18579783] |
Chemical Information
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CAS No. 1166-01-4
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Masse moléculaire 388.64
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Formule C13H12Cl3N7O
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SMILES
O=C(C1=NC(Cl)=C(N)N=C1N)NC(NCC2=CC=C(C(Cl)=C2)Cl)=N
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Synonyms
3',4'-Dichlorobenzamil; L-594881
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Dichlorobenzamil Related Classifications
HY-164684 Related Classifications
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