1166-01-4
1166-01-4
Chemical Structure
Dichlorobenzamil
Synonym(s): 3',4'-Dichlorobenzamil; L-594881
- CAS No.: 1166-01-4
- Formula:C13H12Cl3N7O
- Molecular Weight:388.64
InChIKey: OSHKWEFWXCCNJR-UHFFFAOYSA-N
SMILES: O=C(C1=NC(Cl)=C(N)N=C1N)NC(NCC2=CC=C(C(Cl)=C2)Cl)=N
Biological Activity: Dichlorobenzamil (3',4'-Dichlorobenzamil; L-594881) is an effective Na/Ca exchange inhibitor. Dichlorobenzamil significantly inhibits 45Ca uptake mediated by reverse Na/Ca exchange in pancreatic islet cells (IC50 = 18 μM). Dichlorobenzamil can also block K+ channels and voltage-sensitive Ca2+ channels[1].
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Dichlorobenzamil | Dichlorobenzamil (3',4'-Dichlorobenzamil; L-594881) is an effective Na/Ca exchange inhibitor. Dichlorobenzamil significantly inhibits 45Ca uptake mediated by reverse Na/Ca exchange in pancreatic islet cells (IC50 = 18 μM). Dichlorobenzamil can also block K+ channels and voltage-sensitive Ca2+ channels. | |||||||||||||||||||||
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