Results for "

HAI

" in MedChemExpress (MCE) Product Catalog:

By Targets:	c-Met/HGFR (2) Small Interfering RNA (siRNA) (2)
By Research Areas:	Cancer (2)
Oligonucleotides:	Human Pre-designed siRNA Sets (2) siRNAs (2)

Inhibitors & Agonists

Recombinant Proteins

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-114363A

SRI 31215 TFA 2 Publications Verification	c-Met/HGFR	Cancer
SRI 31215 (TFA) is a Matriptase/Hepsin/hepatocyte growth factor activator (HGFA) triplex inhibitor and mimics the activity of HAI-1/2 (endogenous inhibitors of HGF activation). SRI 31215 has potent inhibitory activity against matriptase, hepsin and HGFA with IC₅₀ values of 0.69 μM, 0.65 μM and 0.30 μM, respectively. SRI 31215 can be used for the research of cancer .

HY-114363

SRI 31215	c-Met/HGFR	Cancer
SRI 31215 is a Matriptase/Hepsin/hepatocyte growth factor activator (HGFA) triplex inhibitor and mimics the activity of HAI-1/2 (endogenous inhibitors of HGF activation). SRI 31215 has potent inhibitory activity against matriptase, hepsin and HGFA with IC₅₀ values of 0.69 μM, 0.65 μM and 0.30 μM, respectively. SRI 31215 can be used for the research of cancer .

HY-RS13685

SPINT1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SPINT1 Human Pre-designed siRNA Set A contains three designed siRNAs for SPINT1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SPINT1 Human Pre-designed siRNA Set A SPINT1 Human Pre-designed siRNA Set A

HY-RS13844

ST14 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
ST14 Human Pre-designed siRNA Set A contains three designed siRNAs for ST14 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

ST14 Human Pre-designed siRNA Set A ST14 Human Pre-designed siRNA Set A

Species:	Human (5) Mouse (4)
Tag:	His (7) Tag Free (1) Avi (2) Fc (1)
Source:	HEK293 (6) E. coli (3)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P73092

	HAI-1 Protein, Mouse (HEK293, Fc) Kunitz-type protease inhibitor 1; HAI-1; SPINT1; HAI1	Mouse	HEK293
	The HAI-1 protein is a multifaceted inhibitor that potently inhibits HGFAC and protects against serine proteases such as ST14/matriptase and TMPRSS13. Through its BPTI/Kunitz inhibitor 1 domain, HAI-1 cleverly coordinates inhibition, engaging in a delicate molecular dance with HGFAC and TMPRSS13. HAI-1 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived HAI-1 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P73091

	HAI-1 Protein, Human (HEK293, His) Kunitz-type protease inhibitor 1; HAI-1; SPINT1; HAI1	Human	HEK293
	HAI-1 Protein serves as an inhibitor of HGFAC, suppressing serine protease activity of ST14/matriptase in vitro and inhibiting TMPRSS13 through the BPTI/Kunitz inhibitor 1 domain. It interacts with HGFAC and TMPRSS13, with the latter interaction promoting TMPRSS13 phosphorylation and cell membrane localization. HAI-1 Protein, Human (HEK293, His) is the recombinant human-derived HAI-1 protein, expressed by HEK293 , with C-His labeled tag.

HY-P705239

	HAI-1 Protein, Human (Biotinylated, HEK293, His-Avi) Kunitz-type protease inhibitor 1; HAI-1; SPINT1; HAI1	Human	HEK293

HY-P705271

	HAI-1 Protein, Mouse (Biotinylated, HEK293, His-Avi) Kunitz-type protease inhibitor 1; HAI-1; SPINT1; HAI1	Mouse	HEK293

HY-P70202

	HAI-2 Protein, Human (HEK293, His) rHuKunitz-type protease inhibitor 2/HAI-2, His; Kunitz-Type Protease Inhibitor 2; Hepatocyte Growth Factor Activator Inhibitor Type 2; HAI-2; Placental Bikunin; SPINT2; HAI2; KOP	Human	HEK293
	HAI-2 protein is a multifunctional inhibitor that regulates multiple cellular processes by potently inhibiting HGFAC and reducing serine protease activity, specifically TMPRSS13 and ST14/matriptase. HAI-2 is good at inhibiting plasmin, plasma and tissue kallikrein, with broad-spectrum inhibitory capabilities. HAI-2 Protein, Human (HEK293, His) is the recombinant human-derived HAI-2 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P76964

	HAI-2 Protein, Mouse (HEK293, His) Kunitz-Type Protease Inhibitor 2; Placental Bikunin; SPINT2; HAI2; KOP	Mouse	HEK293
	HAI-2 Protein functions as an inhibitor for various proteases, including HGFAC, plasmin, and plasma kallikrein.It also inhibits TMPRSS13 and ST14/matriptase, regulating their serine protease activity.The interaction with TMPRSS13 promotes its phosphorylation and cell membrane localization.HAI-2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived HAI-2 protein, expressed by HEK293 , with C-His labeled tag.

HY-P704778

	Matriptase/ST14 Catalytic Domain Protein, Human EC 3.4.21; Epithin; HAI; Matriptase; Membrane-type serine protease 1; MTSP1; MT-SP1EC 3.4.21.109; prostamin; PRSS14; Serine protease 14; Serine protease TADG-15; SNC19; SNC19MTSP1; ST14; suppressor of tumorigenicity 14 protein; TADG15; TADG-15; TMPRSS14; tumor associated differentially expressed gene 15 protein; Tumor-associated differentially-expressed gene 15 protein	Human	E. coli
	The Matriptase/ST14 catalytic domain protein originates from epithelial cells, forms a complex with HAI-1, and is activated by sphingosine-1-phosphate. It cleaves and activates hepatocyte growth factor/scatter factor and urokinase plasminogen activator, suggesting its role as an activator of other proteases and potential growth factors. Matriptase/ST14 Catalytic Domain Protein, Human is the recombinant human-derived Matriptase/ST14 Catalytic Domain protein, expressed by E. coli, with tag free.

HY-P702524

	Matriptase/ST14 Catalytic Domain Protein, Mouse (His) EC 3.4.21; Epithin; HAI; Matriptase; Membrane-type serine protease 1; MTSP1; MT-SP1EC 3.4.21.109; prostamin; PRSS14; Serine protease 14; Serine protease TADG-15; SNC19; SNC19MTSP1; ST14; suppressor of tumorigenicity 14 protein; TADG15; TADG-15; TMPRSS14; tumor associated differentially expressed gene 15 protein; Tumor-associated differentially-expressed gene 15 protein	Mouse	E. coli
	The Matriptase/ST14 catalytic domain protein exhibits serine-type endopeptidase activity and is critical in processes as diverse as placental branching and neural tube closure. It is an extrinsic component of the plasma membrane and is expressed in structures such as the digestive system, early concepts, genitourinary system, pituitary gland, and sense organs. Matriptase/ST14 Catalytic Domain Protein, Mouse (His) is the recombinant mouse-derived Matriptase/ST14 Catalytic Domain protein, expressed by E. coli , with N-6*His labeled tag.

HY-P702523

	Matriptase/ST14 Catalytic Domain Protein, Human (His) EC 3.4.21; Epithin; HAI; Matriptase; Membrane-type serine protease 1; MTSP1; MT-SP1EC 3.4.21.109; prostamin; PRSS14; Serine protease 14; Serine protease TADG-15; SNC19; SNC19MTSP1; ST14; suppressor of tumorigenicity 14 protein; TADG15; TADG-15; TMPRSS14; tumor associated differentially expressed gene 15 protein; Tumor-associated differentially-expressed gene 15 protein	Human	E. coli
	The Matriptase/ST14 catalytic domain protein originates from epithelial cells, forms a complex with HAI-1, and is activated by sphingosine-1-phosphate. It cleaves and activates hepatocyte growth factor/scatter factor and urokinase plasminogen activator, suggesting its role as an activator of other proteases and potential growth factors. Matriptase/ST14 Catalytic Domain Protein, Human (His) is the recombinant human-derived Matriptase/ST14 Catalytic Domain protein, expressed by E. coli , with N-6*His labeled tag.

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Host:	Mouse (2)
Reactivity:	Human (2) Mouse (2) Rat (2) Monkey (2) Dog (2)
Application:	ICC/IF (2) WB (2) FC (2)
Isotype:	IgG1 (2)
Conjugation:	Non-conjugated (2) Biotin (2)
Clonality:	Monoclonal (1)
Modification:	Unmodified (1)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P88149

	SPINT1 Antibody (YA7833) HAI; HAI1; MANSC2	WB, ICC/IF, FC	Human, Dog, Rat, Monkey, Mouse
	SPINT1 Antibody (YA7833) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SPINT1.

HY-P88149A

	SPINT1 Antibody (YA7833)(PBS only) HAI; HAI1; MANSC2	WB, ICC/IF, FC	Human, Dog, Rat, Monkey, Mouse
	SPINT1 Antibody (YA7833) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SPINT1.

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Cat. No.	Product Name		Classification

HY-RS13685

SPINT1 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
SPINT1 Human Pre-designed siRNA Set A contains three designed siRNAs for SPINT1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS13844

ST14 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
ST14 Human Pre-designed siRNA Set A contains three designed siRNAs for ST14 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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