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Inosine+5

" in MedChemExpress (MCE) Product Catalog:

27

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1

Biochemical Assay Reagents

7

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4

Isotope-Labeled Compounds

3

Oligonucleotides

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-108213
    Inosinic acid
    4 Publications Verification

    5'-IMP; IMP; Inosine 5'-dihydrogen phosphate

    		 Endogenous Metabolite Others
    Inosinic acid is an endogenous metabolite. Inosinic acid is used as umami tastant, or as the dietary supplement to improve the yield and meat quality of pigs .
    Inosinic acid
  • HY-W013706
    Inosine-5'-triphosphate trisodium salt

    ITP trisodium salt; Inosine triphosphate trisodium salt

    		 Endogenous Metabolite Metabolic Disease
    Inosine-5'-triphosphate trisodium salt is a nucleotide analogue that acts on multiple G proteins and is widely used in G protein-related research. It can bind to the α -subunit of G proteins and participate in G protein-mediated signal transduction as a substitute for GTP. Its mechanism of action is to interact with the nucleotide-binding site of the G protein α -subunit, affecting the activity and function of G proteins. In the research field, it is mainly used to explore the role of the G protein signaling pathway in cellular physiological and pathological processes. For example, in HL-60 leukemia cells, its impact on G protein-mediated signal transduction can be studied .
    Inosine-5'-triphosphate trisodium salt
  • HY-W013724
    Inosine-5'-diphosphate disodium

    IDP disodium; Inosine-5'-diphosphoric acid disodium

    		 c-Myc Apoptosis Cardiovascular Disease Inflammation/Immunology Cancer
    Inosine-5'-diphosphate disodium (IDP disodium) is a decoy substrate of NM23-H2. Inosine-5'-diphosphate disodium has a superior bond capacity on GDP-binding pocket of NM23-H2 (KD: 5.0 μM). Inosine-5'-diphosphate disodium abrogates c-MYC transcription, induces apoptosis and G2/M cell cycle arrest by disrupting NM23-H2-Pu27-GQ interactions without affecting NM23-H2-mediated kinase properties. Inosine-5'-diphosphate disodium has antihypoxic, antihyperthermic and antiarrhythmic activity and protects animals against the noxious effects of γ-irradiation. Inosine-5'-diphosphate disodium can be used for cancers like Burkitt's lymphoma and cardiovascular diseases research .
    Inosine-5'-diphosphate disodium
  • HY-149101
    Inosine-5'-diphosphate

    IDP; Inosine-5'-diphosphoric acid

    		 c-Myc Apoptosis Cardiovascular Disease Inflammation/Immunology Cancer
    Inosine-5'-diphosphate (IDP) is a decoy substrate of NM23-H2. Inosine-5'-diphosphate has a superior bond capacity on GDP-binding pocket of NM23-H2 (KD: 5.0 μM). Inosine-5'-diphosphate abrogates c-MYC transcription, induces apoptosis and G2/M cell cycle arrest by disrupting NM23-H2-Pu27-GQ interactions without affecting NM23-H2-mediated kinase properties. Inosine-5'-diphosphate has antihypoxic, antihyperthermic and antiarrhythmic activity and protects animals against the noxious effects of γ-irradiation. Inosine-5'-diphosphate can be used for cancers like Burkitt's lymphoma and cardiovascular diseases research .
    Inosine-5'-diphosphate
  • HY-W010759
    Inosine-5′-monophosphate disodium salt octahydrate

    		Endogenous Metabolite Metabolic Disease
    Inosine-5'-monophosphate disodium salt octahydrate is a purine nucleotide that can be used as an umami tastant as well as a precursor of GMP and AMP .
    Inosine-5′-monophosphate disodium salt octahydrate
  • HY-145286
    IMPDH2-IN-2

    		Bacterial Infection Cancer
    IMPDH2-IN-2 is a potent inhibitor of inosine 5’-monophosphate dehydrogenase (IMPDH) with a Ki,app value of 14 μM, respectively. IMPDH2-IN-2 displays moderate antibacterial activity (MIC = 6.3 and 11 μM in minimal GAST/Fe and rich 7H9/ADC/Tween media, respectively). IMPDH2-IN-2 is a potential anti-tuberculosis agent .
    IMPDH2-IN-2
  • HY-108213R
    Inosinic acid (Standard)

    5'-IMP (Standard); IMP (Standard); Inosine 5'-dihydrogen phosphate (Standard)

    		 Reference Standards Endogenous Metabolite Others
    Inosinic acid (Standard) is the analytical standard of Inosinic acid. This product is intended for research and analytical applications. Inosinic acid is an endogenous metabolite. Inosinic acid is an endogenous metabolite. Inosinic acid is used as umami tastant, or as the dietary supplement to improve the yield and meat quality of pigs .
    Inosinic acid (Standard)
  • HY-168509
    IMPDH-IN-1

    		Bacterial Infection
    IMPDH-IN-1 (compound 44) is a bacterial inosine 5'-monophosphate dehydrogenase (IMPDH) inhibitor. IMPDH-IN-1 specifically binds to the catalytic domain of IMPDH. IMPDH-IN-1 potently inhibits the IMPDH of Pseudomonas aeruginosa, Staphylococcus aureus and Escherichia coli .
    IMPDH-IN-1
  • HY-W749117
    Inosine 5′-diphosphate sodium

    		Endogenous Metabolite Metabolic Disease
    Inosine 5’-diphosphate sodium is a purine ribonucleoside 5’-diphosphate with inosine as the nucleobase, which can participate in intracellular energy metabolism and signal transduction processes .
    Inosine 5′-diphosphate sodium
  • HY-118917
    VX-148

    		IMPDH Inflammation/Immunology
    VX-148 is an orally active immunosuppressant, which is a non-competitive inosine-5'-monophosphate dehydrogenase (IMPDH) inhibitor with Ki values for IMPDH Ⅱ and IMPDH Ⅰ of 6 and 14 nM respectively. VX-148 can significantly inhibit the proliferation of human peripheral blood mononuclear cells (PBMC) stimulated by T-cell mitogen (PHA) or B-cell mitogen (SPAS). VX-148 has high selectivity for lymphocytes (such as L1210, Jurkat T cells, and Raji B cells), but has no significant toxicity to non-lymphoid cells. VX-148 can inhibit antibody responses in mouse models and significantly prolong the survival time of transplanted skin in allogeneic skin transplantation models. VX-148 can be used in the research of autoimmune diseases (such as rheumatoid arthritis, psoriasis) and organ transplantation anti-rejection .
    VX-148
  • HY-108213A
    Inosinic acid disodiumhydrate(1:2:X)
    4 Publications Verification

    5'-IMP disodiumhydrate(1:2:X); IMP disodiumhydrate(1:2:X); Inosine 5'-dihydrogen phosphate disodiumhydrate(1:2:X)

    		 Endogenous Metabolite Others
    Inosinic acid (disodium)(hydrate)(1:2:X) (5'-IMP (disodium)(hydrate)(1:2:X)) is an endogenous metabolite. Inosinic acid (disodium)(hydrate)(1:2:X) is used as umami tastant, or as the dietary supplement to improve the yield and meat quality of pigs .
    Inosinic acid disodiumhydrate(1:2:X)
  • HY-164434
    Xanthosine-5'-monophosphate

    5'-Xanthylic acid

    		 Endogenous Metabolite Others
    Xanthosine-5'-monophosphate can be obtained by catalyzing inosine 5'-monophosphate (IMP) with inosine 5'-monophosphate dehydrogenase (IMPDH) .
    Xanthosine-5'-monophosphate
  • HY-W013724S
    Inosine-5'-diphosphate-15N4 dilithium

    IDP-15N4 dilithium; Inosine-5'-diphosphoric acid-15N4 disodium

    		 Isotope-Labeled Compounds c-Myc Apoptosis Cardiovascular Disease Inflammation/Immunology Cancer
    Inosine-5'-diphosphate- 15N4 dilithium (IDP- 15N4 dilithium) is 15N labeled Inosine-5'-diphosphate dilithium. Inosine-5'-diphosphate (IDP) is a decoy substrate of NM23-H2. Inosine-5'-diphosphate has a superior bond capacity on GDP-binding pocket of NM23-H2 (KD: 5.0 μM). Inosine-5'-diphosphate abrogates c-MYC transcription, induces apoptosis and G2/M cell cycle arrest by disrupting NM23-H2-Pu27-GQ interactions without affecting NM23-H2-mediated kinase properties. Inosine-5'-diphosphate has antihypoxic, antihyperthermic and antiarrhythmic activity and protects animals against the noxious effects of γ-irradiation. Inosine-5'-diphosphate can be used for cancers like Burkitt's lymphoma and cardiovascular diseases research .
    Inosine-5'-diphosphate-15N4 dilithium
  • HY-141635
    cis-11,14-Eicosadienoic acid methyl ester

    		Endogenous Metabolite Metabolic Disease
    cis-11,14-Eicosadienoic acid methyl ester is a more lipid soluble form of the ω-6 C20-2 fatty acid 11(Z),14(Z)-eicosadienoic acid, a naturally occurring PUFA. 11(Z),14(Z)-Eicosadienoic acid competitively inhibits inosine 5’-monophosphate dehydrogenase (Ki=3.1 μM) and inhibits the binding of LTB4 to its receptor on neutrophils (Ki=3.0 μM). Also, serum levels of eicosadienoic acids negatively correlate with degree of sleep disturbance.3 Eicosadienoic acids are converted by desaturases, in vivo, to eicosatrienoic acids, which are potent vasodilators.
    cis-11,14-Eicosadienoic acid methyl ester
  • HY-173533
    2-Chloro TNP-ITP tetrasodium

    2-Chloro TNP-Inosine 5'-triphosphate tetrasodium

    		 Drug Derivative Others
    2-Chloro TNP-ITP (2-Chloro TNP-Inosine 5'-triphosphate) tetrasodium is an analog of Inosine-5'-triphosphate trisodium salt (HY-W013706) .
    2-Chloro TNP-ITP tetrasodium
  • HY-108213S1
    Inosinic acid-15N4 dilithium

    5'-IMP-15N4 dilithium; IMP-15N4 dilithium; Inosine 5'-dihydrogen phosphate-15N4 dilithium

    		 Isotope-Labeled Compounds Others
    Inosinic acid- 15N4 dilithium (5'-IMP-15N4 (dilithium); IMP-15N4 (dilithium); Inosine 5'-(dihydrogen phosphate)-15N4 (dilithium)) is 15N-labeled Inosinic acid (HY-108213). Inosinic acid is an endogenous metabolite. Inosinic acid is used as umami tastant, or as the dietary supplement to improve the yield and meat quality of pigs .
    Inosinic acid-15N4 dilithium
  • HY-W769319
    Inosinic acid-13C5

    5'-IMP-13C5; IMP-13C5; Inosine 5'-dihydrogen phosphate-13C5

    		 Isotope-Labeled Compounds Endogenous Metabolite Others
    Inosinic acid- 13C5 (5'-IMP- 13C5) is the 13C-labeled Inosinic acid (HY-108213). Inosinic acid is an endogenous metabolite. Inosinic acid is used as umami tastant, or as the dietary supplement to improve the yield and meat quality of pigs .
    Inosinic acid-13C5
  • HY-108213AR
    Inosinic acid disodiumhydrate(1:2:X) (Standard)

    5'-IMP disodiumhydrate(1:2:X) (Standard); IMP disodiumhydrate(1:2:X) (Standard); Inosine 5'-dihydrogen phosphate disodiumhydrate(1:2:X) (Standard)

    		 Reference Standards Endogenous Metabolite Others
    Inosinic acid (disodium)(hydrate)(1:2:X) (Standard) is the analytical standard of Inosinic acid (disodium)(hydrate)(1:2:X). This product is intended for research and analytical applications. Inosinic acid (disodium)(hydrate)(1:2:X) (5'-IMP (disodium)(hydrate)(1:2:X)) is an endogenous metabolite. Inosinic acid (disodium)(hydrate)(1:2:X) is used as umami tastant, or as the dietary supplement to improve the yield and meat quality of pigs .
    Inosinic acid disodiumhydrate(1:2:X) (Standard)
  • HY-E70516
    Inosine-5'-monophosphate dehydrogenase, Microorganism

    		Others Others
    Inosine-5'-monophosphate dehydrogenase, Microorganism (EC 1.1.1.205) catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth .
    Inosine-5'-monophosphate dehydrogenase, Microorganism
  • HY-150172A
    Inosine 5'-triphosphate lithium salt

    ITP lithium salt; Inosine triphosphate lithium salt

    		 Endogenous Metabolite Metabolic Disease
    Inosine-5'-triphosphate (ITP) lithium salt is a nucleotide analogue that acts on multiple G proteins. Inosine-5'-triphosphate lithium salt can bind to the α -subunit of G proteins and participate in G protein-mediated signal transduction as a substitute for GTP. Inosine-5'-triphosphate lithium salt interacts with the nucleotide-binding site of the G protein α -subunit, affecting the activity and function of G proteins. Inosine-5'-triphosphate lithium salt is used to explore the role of the G protein signaling pathway in cellular physiological and pathological processes .
    Inosine 5'-triphosphate lithium salt
  • HY-173531
    8-Bromo TNP-ITP tetrasodium

    8-Bromo TNP-Inosine 5'-triphosphate tetrasodium

    		 Drug Derivative Others
    8-Bromo TNP-ITP (8-Bromo TNP-Inosine 5'-triphosphate) tetrasodium is an analog of Inosine-5'-triphosphate trisodium salt (HY-W013706) .
    8-Bromo TNP-ITP tetrasodium
  • HY-W013706R
    Inosine-5'-triphosphate trisodium salt (Standard)

    ITP trisodium salt (Standard); Inosine triphosphate trisodium salt (Standard)

    		 Endogenous Metabolite Reference Standards Metabolic Disease
    Inosine-5'-triphosphate (trisodium salt) (Standard) is the analytical standard of Inosine-5'-triphosphate (trisodium salt) (HY-W013706). This product is intended for research and analytical applications. Inosine-5'-triphosphate trisodium salt is a nucleotide analogue that acts on multiple G proteins and is widely used in G protein-related research. It can bind to the α -subunit of G proteins and participate in G protein-mediated signal transduction as a substitute for GTP. Its mechanism of action is to interact with the nucleotide-binding site of the G protein α -subunit, affecting the activity and function of G proteins. In the research field, it is mainly used to explore the role of the G protein signaling pathway in cellular physiological and pathological processes. For example, in HL-60 leukemia cells, its impact on G protein-mediated signal transduction can be studied .
    Inosine-5'-triphosphate trisodium salt (Standard)
  • HY-173532
    2-Methylthio TNP-ITP tetrasodium

    2-Methylthio TNP-Inosine 5'-triphosphate tetrasodium

    		 Fluorescent Dye Others
    2-Methylthio TNP-ITP (2-Methylthio TNP-Inosine 5'-triphosphate) tetrasodium is a fluorescent derivative of inosine triphosphate (ITP) with a TNP (2,4,6-trinitrophenyl) fluorophore .
    2-Methylthio TNP-ITP tetrasodium
  • HY-172667
    2-Chloroinosine-5'-O-triphosphate sodium

    		Biochemical Assay Reagents Others
    2-Chloroinosine-5'-O-triphosphate (sodium) is a derivative of inosine 5'-triphosphate.
    2-Chloroinosine-5'-O-triphosphate sodium
  • HY-134278A
    8-Bromoinosine-5'-O-triphosphate tetrasodium

    8-Br-ITP tetrasodium; 8-Bromo ITP tetrasodium

    		 Nucleoside Antimetabolite/Analog Others
    8-Bromoinosine-5'-O-triphosphate (8-Br-ITP) tetrasodium is a derivative of the nucleoside triphosphate Inosine-5'-triphosphate (ITP) (HY-W013706). 8-Bromoinosine-5'-O-triphosphate tetrasodium can be used in the determination of nucleoside diphosphate kinase (NDPK) activity .
    8-Bromoinosine-5'-O-triphosphate tetrasodium
  • HY-W743767
    Mizoribine 5'-monophosphate

    MZR-P

    		 IMPDH Parasite Drug Metabolite Infection Inflammation/Immunology
    Mizoribine 5'-monophosphate (MZR-P) is the active metabolite of Mizoribine (HY-17470). Mizoribine 5'-monophosphate is an inhibitor of inosine-5'-monophosphate dehydrogenase (IMPDH), and its Ki values for IMPDH of Trypanosoma brucei, Bacillus subtilis and Oceanobacillus iheyensis are 3.3, 72 and 157 nM respectively. Mizoribine 5'-monophosphate can be used in anti-trypanosomiasis and immunosuppression research .
    Mizoribine 5'-monophosphate
  • HY-W769319A
    Inosinic acid-13C5 TEA

    5'-IMP-13C5 TEA; IMP-13C5 TEA; Inosine 5'-dihydrogen phosphate-13C5 TEA

    		 Isotope-Labeled Compounds Endogenous Metabolite Others
    Inosinic acid- 13C5 (5'-IMP- 13C5) TEA is the 13C-labeled Inosinic acid (HY-108213). Inosinic acid is an endogenous metabolite. Inosinic acid is used as umami tastant, or as the dietary supplement to improve the yield and meat quality of pigs .
    Inosinic acid-13C5 TEA

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