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Inosine-5'-diphosphate-15N4 dilithium

(Synonyms: IDP-15N4 dilithium; Inosine-5'-diphosphoric acid-15N4 disodium)

Inosine-5'-diphosphate-15N4 dilithium (IDP-15N4 dilithium) is 15N labeled Inosine-5'-diphosphate dilithium. Inosine-5'-diphosphate (IDP) is a decoy substrate of NM23-H2. Inosine-5'-diphosphate has a superior bond capacity on GDP-binding pocket of NM23-H2 (KD: 5.0 μM). Inosine-5'-diphosphate abrogates c-MYC transcription, induces apoptosis and G2/M cell cycle arrest by disrupting NM23-H2-Pu27-GQ interactions without affecting NM23-H2-mediated kinase properties. Inosine-5'-diphosphate has antihypoxic, antihyperthermic and antiarrhythmic activity and protects animals against the noxious effects of γ-irradiation. Inosine-5'-diphosphate can be used for cancers like Burkitt's lymphoma and cardiovascular diseases research.

For research use only. We do not sell to patients.

  • Formula: C10H12Li215N4O11P2
  • Molecular Weight:444.03
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Inosine-5'-diphosphate-15N4 dilithium Chemical Structure
    Inosine-5'-diphosphate-15N4 dilithium Chemical Structure
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  • Inosine-5'-diphosphate-15N4 dilithium Chemical Structure
    Inosine-5'-diphosphate-15N4 dilithium Chemical Structure
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  • Inosine-5'-diphosphate-15N4 dilithium