cis-11,14-Eicosadienoic acid methyl ester

Cat. No.: HY-141635 Purity: 98.05%: Data Sheet
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cis-11,14-Eicosadienoic acid methyl ester is a more lipid soluble form of the ω-6 C20-2 fatty acid 11(Z),14(Z)-eicosadienoic acid, a naturally occurring PUFA. 11(Z),14(Z)-Eicosadienoic acid competitively inhibits inosine 5’-monophosphate dehydrogenase (Ki=3.1 μM) and inhibits the binding of LTB4 to its receptor on neutrophils (Ki=3.0 μM). Also, serum levels of eicosadienoic acids negatively correlate with degree of sleep disturbance.3 Eicosadienoic acids are converted by desaturases, in vivo, to eicosatrienoic acids, which are potent vasodilators.

For research use only. We do not sell to patients.

cis-11,14-Eicosadienoic acid methyl ester Chemical Structure

CAS No. : 61012-46-2

Size	Stock	Quantity
Solvent
5 mg (155.02 mM * 100 μL in Ethanol)	In-stock	Estimated Time of Arrival: December 31
Solvent
10 mg (155.02 mM * 200 μL in Ethanol)	In-stock	Estimated Time of Arrival: December 31

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Description	cis-11,14-Eicosadienoic acid methyl ester is a more lipid soluble form of the ω-6 C20-2 fatty acid 11(Z),14(Z)-eicosadienoic acid, a naturally occurring PUFA. 11(Z),14(Z)-Eicosadienoic acid competitively inhibits inosine 5’-monophosphate dehydrogenase (Ki=3.1 μM) and inhibits the binding of LTB4 to its receptor on neutrophils (Ki=3.0 μM). Also, serum levels of eicosadienoic acids negatively correlate with degree of sleep disturbance.3 Eicosadienoic acids are converted by desaturases, in vivo, to eicosatrienoic acids, which are potent vasodilators.
Molecular Weight	322.53
Formula	C₂₁H₃₈O₂
CAS No.	61012-46-2
Appearance	Liquid
Color	Colorless to light yellow
SMILES	CCCCC/C=C\C/C=C\CCCCCCCCCC(OC)=O
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Solution, -20°C, 2 years
Purity & Documentation	Purity: 98.05% Select Batch: Data Sheet (259 KB) SDS (396 KB) COA (237 KB) HNMR (227 KB) RP-HPLC (268 KB) MS (151 KB) Handling Instructions (2659 KB)
References	[1]. Yagaloff, et al. Essential fatty acids are antagonists of the leukotriene B4 receptor. Prostaglandins, Leukot. Essent. Fatty Acids 52(5), 293-297 (1995).