61012-46-2
Chemical Structure
cis-11,14-Eicosadienoic acid methyl ester
- CAS No.: 61012-46-2
- Formula:C21H38O2
- Molecular Weight:322.53
IUPAC Name: methyl (11Z,14Z)-icosa-11,14-dienoate
InChIKey: GWJCFAOQCNNFAM-NQLNTKRDSA-N
SMILES: CCCCC/C=C\C/C=C\CCCCCCCCCC(OC)=O
Biological Activity: cis-11,14-Eicosadienoic acid methyl ester is a more lipid soluble form of the ω-6 C20-2 fatty acid 11(Z),14(Z)-eicosadienoic acid, a naturally occurring PUFA. 11(Z),14(Z)-Eicosadienoic acid competitively inhibits inosine 5’-monophosphate dehydrogenase (Ki=3.1 μM) and inhibits the binding of LTB4 to its receptor on neutrophils (Ki=3.0 μM). Also, serum levels of eicosadienoic acids negatively correlate with degree of sleep disturbance.3 Eicosadienoic acids are converted by desaturases, in vivo, to eicosatrienoic acids, which are potent vasodilators.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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cis-11,14-Eicosadienoic acid methyl ester | 98.05% | cis-11,14-Eicosadienoic acid methyl ester is a more lipid soluble form of the ω-6 C20-2 fatty acid 11(Z),14(Z)-eicosadienoic acid, a naturally occurring PUFA. 11(Z),14(Z)-Eicosadienoic acid competitively inhibits inosine 5’-monophosphate dehydrogenase (Ki=3.1 μM) and inhibits the binding of LTB4 to its receptor on neutrophils (Ki=3.0 μM). Also, serum levels of eicosadienoic acids negatively correlate with degree of sleep disturbance.3 Eicosadienoic acids are converted by desaturases, in vivo, to eicosatrienoic acids, which are potent vasodilators. | ||||||||||||||||||||
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