Mizoribine 5'-monophosphate
Mizoribine 5'-monophosphate (MZR-P) is the active metabolite of Mizoribine (HY-17470). Mizoribine 5'-monophosphate is an inhibitor of inosine-5'-monophosphate dehydrogenase (IMPDH), and its Ki values for IMPDH of Trypanosoma brucei, Bacillus subtilis and Oceanobacillus iheyensis are 3.3, 72 and 157 nM respectively. Mizoribine 5'-monophosphate can be used in anti-trypanosomiasis and immunosuppression research.
For research use only. We do not sell to patients.
- CAS No.: 62025-48-3
- Formula: C9H14N3O9P
- Molecular Weight:339.20
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Biological Activity
Chemical Information
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CAS No. 62025-48-3
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Molecular Weight 339.20
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Formula C9H14N3O9P
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SMILES
O[C@H]1[C@@H](O)[C@H](N2C(O)=C(C(N)=O)N=C2)O[C@@H]1COP(O)(O)=O
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Synonyms
MZR-P
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Ota H, et al. A novel enzymatic method for measuring mizoribine 5'-monophosphate levels in serum. J Biosci Bioeng. 2008 Nov;106(5):511-4. [Content Brief]
[2]. Bessho T, et al. Characterization of the novel Trypanosoma brucei inosine 5'-monophosphate dehydrogenase. Parasitology. 2013 May;140(6):735-45. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Mizoribine 5'-monophosphate Related Classifications
HY-W743767 Related Classifications
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