Search Result
Results for "
Mal-PEG2000-mal
" in MedChemExpress (MCE) Product Catalog:
10
Biochemical Assay Reagents
1
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
-
- HY-167036
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DMG-PEG2000-Mal is a pegylated lipid with a molecular weight of 2000. DMG-PEG-Mal serves as a component of lipid nanoparticles for mRNA delivery .
|
-
-
- HY-140719
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-PEG2000-mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-172279A
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG2000-TAT is a cell-penetrating peptide-modified PEGylated phospholipid conjugate and cellular uptake enhancer. DSPE-PEG2000-TAT forms via conjugation of Cys-TAT to DSPE-PEG2000-Mal. DSPE-PEG2000-TAT enhances liposomal cellular uptake and siRNA transfection efficiency in glomerular mesangial and macrophage cells. DSPE-PEG2000-TAT can be used for drug delivery .
|
-
-
- HY-W440719
-
|
|
Liposome
|
Cancer
|
|
Cholesterol-PEG2000-MAL is a PEG derivative and can be used to prepare liposome or nanoparticle due to its ability to self-assemble in water. The maleimide moiety is reactive with thiol molecule to form a covalent thioether bond.
|
-
-
- HY-P10392AF
-
|
|
Wnt
β-catenin
|
Cancer
|
|
fStAx-35R TFA is the hydrocarbon-stapled peptide. fStAx-35R TFA inhibits Wnt/β-catenin signaling pathway by disrupting the β-catenin-TCF interaction. fStAx-35R TFA can be used in cancer research .
|
-
-
- HY-166990B
-
-
-
- HY-172699
-
|
|
Liposome
LDLR
|
Cancer
|
|
DSPE-PEG2000-ANG is a conjugate of DSPE-PEG2000-MAL and Angiopep-2. Angiopep-2 is a peptide ligand that targets LRP-1. DSPE-PEG2000-ANG is used to synthesize gadolinium-boron bifunctionalized lipid nanoparticles BPA-F&DOTA-Gd@LIPO-ANG with blood-brain barrier and glioma targeting properties .
|
-
-
- HY-P10896
-
|
|
Bombesin Receptor
|
Cancer
|
|
NOTA-P2-RM26 is an antagonist of Bombesin (HY-P0195) analogs, and the gastrin-releasing peptide receptor (GRPR/BB2) is a molecular target for prostate cancer visualization. NOTA-P2-RM26 is labeled with 111In and 68Ga for prostate cancer imaging studies using PET and SPECT/CT .
|
-
-
- HY-140689
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG2000-mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-W440995
-
|
|
Liposome
|
Cancer
|
|
DOPE-PEG2000-Mal is a phospholipid polyPEG which can be used to prepare liposomes or nanoparticles. It is also reactive with thiol at pH 6.5 tp 7.5 to form a stable thioether bond.
|
-
-
- HY-174953A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
TPP-PEG2000-Mal is a PEG derivative composed of triphenyl phosphate (TPP), PEG units, and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .
|
-
-
- HY-174927D
-
|
DBCO-PEG2000-mal
|
Biochemical Assay Reagents
|
Others
|
|
DBCO-PEG2000-Maleimide (DBCO-PEG2000-Mal) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG2000-Maleimide contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .
|
-
-
- HY-D2885C
-
|
Rhodamine B-PEG2000-mal
|
Fluorescent Dye
|
Others
|
|
RB-PEG2000-Mal (Rhodamine B-PEG2000-Mal) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Maleimide (HY-W007324) (Mal). RB-PEG2000-Mal can be used for fluorescent labeling and imaging (Ex/Em=546/610 nm) .
|
-
-
- HY-W1052262
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Silane-PEG2000-Mal is a PEG derivative that can be used to modify proteins, peptides and other materials. Silane-PEG2000-Mal can be used for peptide modification and drug delivery .
|
-
-
- HY-169232
-
|
|
PROTACs
|
Cancer
|
|
PCC16 chloride is a CRBN-based cp-PCC with an IC50 value of 102 nM for the degradation of DHHC3. PCC16 chloride has antitumor activity. (Target protein ligand: HY-169235, linker: HY-169236, E3 ligase ligand: HY-10984) .
|
-
-
- HY-W440950
-
|
|
Liposome
|
Others
|
|
Stearic acid-PEG2000-Mal enables surface modification of various substrate through reaction between hydroxyl and ethoxyl silane. The polymer can be used for click chemistry with alkyne containing molecule.
|
-
-
- HY-W1052492
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DPPE-PEG2000-Mal is a conjugate composed of DPPE, PEG chains, and maleimide (Mal). The maleimide group in DPPE-PEG2000-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
|
-
-
- HY-183126A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSG-PEG2000-Mal is a conjugate composed of DSG, PEG chains, and maleimide (Mal). The maleimide group in DSG-PEG2000-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
|
-
-
- HY-W1052227
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DMPE-PEG2000-Mal is a conjugate composed of DMPE, PEG chains, and maleimide (Mal). The maleimide group in DMPE-PEG2000-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
|
-
-
- HY-P11625
-
|
|
RXFP Receptor
|
Cardiovascular Disease
|
|
R9-13 is a fatty acid-conjugated relaxin and an agonist of LGR7 (RXFP1). R9-13 induces sustained pubic symphysis elongation in estrogen-pretreated mice. R9-13 exhibits long-acting pharmacokinetic profiles in rodents, with in vivo activity lasting up to one week after administration. R9-13 can be used in studies related to acute heart failure .
|
-
-
- HY-P11830
-
|
|
Amylin Receptor
|
Metabolic Disease
|
|
UDA-6 is a potent calcitonin and amylin receptor agonist (DACRA). UDA-6 induces weight loss, improves metabolic and hepatic parameters, and stabilizes active receptor states in obesity rats. UDA-6 can be used for the research of obesity .
|
-
-
- HY-P11596
-
|
|
Integrin
|
Cancer
|
|
NOTA-Asp2-αvβ6L is an integrin αvβ6 binder with selective accumulation in αvβ6-positive pancreatic cancer cells and tumors. NOTA-Asp2-αvβ6L can be used as a PET/CT tracer for imaging pancreatic ductal adenocarcinoma (PDAC) .
|
-
-
- HY-P3252AS
-
|
|
Isotope-Labeled Compounds
Complement System
|
Inflammation/Immunology
|
|
Pegcetacoplan- 13C3, 15N TFA is the 13C- and 15N-labeled Pegcetacoplan TFA. Pegcetacoplan is a pegylated complement C3/C3b inhibitor. Pegcetacoplan acts by specifically binding to and inhibiting C3 and C3b, thereby suppressing the complement cascade at its proximal stage. Pegcetacoplan is not a known inhibitor or inducer of CYP450 isoenzymes. Pegcetacoplan can be used for the research of complement-mediated diseases, including paroxysmal nocturnal hemoglobinuria (PNH) and age-related macular degeneration (AMD).
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-D2885C
-
|
Rhodamine B-PEG2000-mal
|
Fluorescent Dyes
|
|
RB-PEG2000-Mal (Rhodamine B-PEG2000-Mal) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Maleimide (HY-W007324) (Mal). RB-PEG2000-Mal can be used for fluorescent labeling and imaging (Ex/Em=546/610 nm) .
|
| Cat. No. |
Product Name |
Type |
-
- HY-167036
-
|
|
Biochemical Assay Reagents
|
|
DMG-PEG2000-Mal is a pegylated lipid with a molecular weight of 2000. DMG-PEG-Mal serves as a component of lipid nanoparticles for mRNA delivery .
|
-
- HY-172279A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG2000-TAT is a cell-penetrating peptide-modified PEGylated phospholipid conjugate and cellular uptake enhancer. DSPE-PEG2000-TAT forms via conjugation of Cys-TAT to DSPE-PEG2000-Mal. DSPE-PEG2000-TAT enhances liposomal cellular uptake and siRNA transfection efficiency in glomerular mesangial and macrophage cells. DSPE-PEG2000-TAT can be used for drug delivery .
|
-
- HY-166990B
-
|
MeO-PEG2000-mal
|
Biochemical Assay Reagents
|
|
Methoxypolyethylene glycol maleimide 2000 (MeO-PEG2000-Mal) is a protein PEGylation reagent .
|
-
- HY-172699
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG2000-ANG is a conjugate of DSPE-PEG2000-MAL and Angiopep-2. Angiopep-2 is a peptide ligand that targets LRP-1. DSPE-PEG2000-ANG is used to synthesize gadolinium-boron bifunctionalized lipid nanoparticles BPA-F&DOTA-Gd@LIPO-ANG with blood-brain barrier and glioma targeting properties .
|
-
- HY-174953A
-
|
|
Biochemical Assay Reagents
|
|
TPP-PEG2000-Mal is a PEG derivative composed of triphenyl phosphate (TPP), PEG units, and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .
|
-
- HY-174927D
-
|
DBCO-PEG2000-mal
|
Biochemical Assay Reagents
|
|
DBCO-PEG2000-Maleimide (DBCO-PEG2000-Mal) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG2000-Maleimide contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .
|
-
- HY-W1052262
-
|
|
Biochemical Assay Reagents
|
|
Silane-PEG2000-Mal is a PEG derivative that can be used to modify proteins, peptides and other materials. Silane-PEG2000-Mal can be used for peptide modification and drug delivery .
|
-
- HY-W1052492
-
|
|
Biochemical Assay Reagents
|
|
DPPE-PEG2000-Mal is a conjugate composed of DPPE, PEG chains, and maleimide (Mal). The maleimide group in DPPE-PEG2000-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
|
-
- HY-183126A
-
|
|
Biochemical Assay Reagents
|
|
DSG-PEG2000-Mal is a conjugate composed of DSG, PEG chains, and maleimide (Mal). The maleimide group in DSG-PEG2000-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
|
-
- HY-W1052227
-
|
|
Biochemical Assay Reagents
|
|
DMPE-PEG2000-Mal is a conjugate composed of DMPE, PEG chains, and maleimide (Mal). The maleimide group in DMPE-PEG2000-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P10392AF
-
|
|
Wnt
β-catenin
|
Cancer
|
|
fStAx-35R TFA is the hydrocarbon-stapled peptide. fStAx-35R TFA inhibits Wnt/β-catenin signaling pathway by disrupting the β-catenin-TCF interaction. fStAx-35R TFA can be used in cancer research .
|
-
- HY-P10896
-
|
|
Bombesin Receptor
|
Cancer
|
|
NOTA-P2-RM26 is an antagonist of Bombesin (HY-P0195) analogs, and the gastrin-releasing peptide receptor (GRPR/BB2) is a molecular target for prostate cancer visualization. NOTA-P2-RM26 is labeled with 111In and 68Ga for prostate cancer imaging studies using PET and SPECT/CT .
|
-
- HY-169232
-
|
|
PROTACs
|
Cancer
|
|
PCC16 chloride is a CRBN-based cp-PCC with an IC50 value of 102 nM for the degradation of DHHC3. PCC16 chloride has antitumor activity. (Target protein ligand: HY-169235, linker: HY-169236, E3 ligase ligand: HY-10984) .
|
-
- HY-P11625
-
|
|
RXFP Receptor
|
Cardiovascular Disease
|
|
R9-13 is a fatty acid-conjugated relaxin and an agonist of LGR7 (RXFP1). R9-13 induces sustained pubic symphysis elongation in estrogen-pretreated mice. R9-13 exhibits long-acting pharmacokinetic profiles in rodents, with in vivo activity lasting up to one week after administration. R9-13 can be used in studies related to acute heart failure .
|
-
- HY-P11830
-
|
|
Amylin Receptor
|
Metabolic Disease
|
|
UDA-6 is a potent calcitonin and amylin receptor agonist (DACRA). UDA-6 induces weight loss, improves metabolic and hepatic parameters, and stabilizes active receptor states in obesity rats. UDA-6 can be used for the research of obesity .
|
-
- HY-P11596
-
|
|
Integrin
|
Cancer
|
|
NOTA-Asp2-αvβ6L is an integrin αvβ6 binder with selective accumulation in αvβ6-positive pancreatic cancer cells and tumors. NOTA-Asp2-αvβ6L can be used as a PET/CT tracer for imaging pancreatic ductal adenocarcinoma (PDAC) .
|
-
- HY-P3252AS
-
|
|
Isotope-Labeled Compounds
Complement System
|
Inflammation/Immunology
|
|
Pegcetacoplan- 13C3, 15N TFA is the 13C- and 15N-labeled Pegcetacoplan TFA. Pegcetacoplan is a pegylated complement C3/C3b inhibitor. Pegcetacoplan acts by specifically binding to and inhibiting C3 and C3b, thereby suppressing the complement cascade at its proximal stage. Pegcetacoplan is not a known inhibitor or inducer of CYP450 isoenzymes. Pegcetacoplan can be used for the research of complement-mediated diseases, including paroxysmal nocturnal hemoglobinuria (PNH) and age-related macular degeneration (AMD).
|
| Cat. No. |
Product Name |
Chemical Structure |
-
- HY-P3252AS
-
|
|
|
Pegcetacoplan- 13C3, 15N TFA is the 13C- and 15N-labeled Pegcetacoplan TFA. Pegcetacoplan is a pegylated complement C3/C3b inhibitor. Pegcetacoplan acts by specifically binding to and inhibiting C3 and C3b, thereby suppressing the complement cascade at its proximal stage. Pegcetacoplan is not a known inhibitor or inducer of CYP450 isoenzymes. Pegcetacoplan can be used for the research of complement-mediated diseases, including paroxysmal nocturnal hemoglobinuria (PNH) and age-related macular degeneration (AMD).
|
-
| Cat. No. |
Product Name |
|
Classification |
-
- HY-174927D
-
|
DBCO-PEG2000-mal
|
|
DBCO
|
|
DBCO-PEG2000-Maleimide (DBCO-PEG2000-Mal) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG2000-Maleimide contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .
|
| Cat. No. |
Product Name |
|
Classification |
-
- HY-167036
-
|
|
|
Pegylated Lipids
|
|
DMG-PEG2000-Mal is a pegylated lipid with a molecular weight of 2000. DMG-PEG-Mal serves as a component of lipid nanoparticles for mRNA delivery .
|
-
- HY-172279A
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG2000-TAT is a cell-penetrating peptide-modified PEGylated phospholipid conjugate and cellular uptake enhancer. DSPE-PEG2000-TAT forms via conjugation of Cys-TAT to DSPE-PEG2000-Mal. DSPE-PEG2000-TAT enhances liposomal cellular uptake and siRNA transfection efficiency in glomerular mesangial and macrophage cells. DSPE-PEG2000-TAT can be used for drug delivery .
|
-
- HY-W440719
-
|
|
|
Pegylated Lipids
|
|
Cholesterol-PEG2000-MAL is a PEG derivative and can be used to prepare liposome or nanoparticle due to its ability to self-assemble in water. The maleimide moiety is reactive with thiol molecule to form a covalent thioether bond.
|
-
- HY-172699
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG2000-ANG is a conjugate of DSPE-PEG2000-MAL and Angiopep-2. Angiopep-2 is a peptide ligand that targets LRP-1. DSPE-PEG2000-ANG is used to synthesize gadolinium-boron bifunctionalized lipid nanoparticles BPA-F&DOTA-Gd@LIPO-ANG with blood-brain barrier and glioma targeting properties .
|
-
- HY-W440995
-
|
|
|
Pegylated Lipids
|
|
DOPE-PEG2000-Mal is a phospholipid polyPEG which can be used to prepare liposomes or nanoparticles. It is also reactive with thiol at pH 6.5 tp 7.5 to form a stable thioether bond.
|
-
- HY-W440950
-
|
|
|
Pegylated Lipids
|
|
Stearic acid-PEG2000-Mal enables surface modification of various substrate through reaction between hydroxyl and ethoxyl silane. The polymer can be used for click chemistry with alkyne containing molecule.
|
Your information is safe with us. * Required Fields.
Inquiry Information
- Product Name:
- Cat. No.:
- Quantity:
- MCE Japan Authorized Agent:
