Search Result
Results for "
PG(16:0/0:0)-d31
" in MedChemExpress (MCE) Product Catalog:
52
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-N0830S2
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- HY-146896S
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- HY-130462S
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POPC-d31
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Isotope-Labeled Compounds
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Others
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1-Palmitoyl-2-oleoyl-sn-glycero-3-PC-d31 is deuterium labeled 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (POPC), a phospholipid, is a major component of biological membranes. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC is used for
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- HY-N0830BS3
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- HY-100354S4
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- HY-146882S
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- HY-128922S
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- HY-125783S1
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- HY-146885S
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- HY-146877S
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- HY-N1482S1
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Parasite
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Inflammation/Immunology
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Methyl palmitate-d31 is the deuterium labeled Methyl palmitate. Methyl palmitate, an acaricidal compound occurring in green walnut husks, inhibits phagocytic activity and immune response. Methyl palmitate also posseses anti-inflammatory and antifibrotic effects .
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- HY-N2086S
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Ethyl hexadecanoate-d31
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Isotope-Labeled Compounds
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Others
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Ethyl palmitate-d31 is the deuterium labeled Ethyl palmitate. Ethyl palmitate, a fatty acid ethyl ester (FAEE), shows a marked preference for the synthesis of ethyl palmitate and ethyl oleate over other FAEEs in human subjects after ethanol consumption. Ethyl palmitate is used as a hair- and skin-conditioning agent .
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- HY-W013061S2
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Endogenous Metabolite
Isotope-Labeled Compounds
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Metabolic Disease
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Propane-1,2,3-triyl tripalmitate-d31 is the deuterium labeled Propane-1,2,3-triyl tripalmitate (HY-W013061). Propane-1,2,3-triyl tripalmitate is a saturated fat. Propane-1,2,3-triyl tripalmitate enhances the lymphatic transport of Glycerol tristearate (HY-127035) .
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- HY-116193S
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- HY-32351B
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3-epi-25-Hydroxy cholecalciferol
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PTHR
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Endocrinology
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3-epi-25-hydroxy Vitamin D3 is the C-3 epimer of 25-hydroxy vitamin D3.1 Dietary administration of 3-epi-25-hydroxy vitamin D3 (0.5 and 1 IU/g) decreases levels of serum parathyroid hormone (PTH) in male, but not female, weanling rats.
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- HY-W074890S
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- HY-141629S
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- HY-W010708S2
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- HY-B1465S
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Endogenous Metabolite
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Others
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1-Hexadecanol-d31 is the deuterium labeled 1-Hexadecanol . 1-Hexadecanol is a fatty alcohol, a lipophilic substrate .
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- HY-146891S
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- HY-146892S
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129Y83-d31
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Isotope-Labeled Compounds
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Others
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1-Palmitoyl-2-palmitoyl-sn-glycero-3-phosphocholine-d31 is deuterium labeled 1-Palmitoyl-2-palmitoyl-sn-glycero-3-phosphocholine.
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- HY-W701599
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Oxiran-2-ylmethyl palmitate-d31
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Isotope-Labeled Compounds
Biochemical Assay Reagents
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Others
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Oxiran-2-ylmethyl hexadecanoate-d31 is deuterium labeled Glycidyl palmitate. Glycidyl Palmitate is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
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- HY-146875S
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Isotope-Labeled Compounds
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Others
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1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoinositol-d31 (ammonium) is deuterium labeled 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoinositol (ammonium).
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- HY-15592S2
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GSK-1265744-d3-1; S/GSK1265744-d3-1
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Isotope-Labeled Compounds
HIV Integrase
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Infection
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Cabotegravir d3-1 (GSK-1265744-d3-1) is a deuterium substitute of Cabotegravir. Cabotegravir is a potent HIV integrase inhibitor used in AIDS research
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- HY-W134007S3
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- HY-120657S1
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Isotope-Labeled Compounds
CGRP Receptor
NF-κB
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Others
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9-PAHSA-d31 is the deuterium labeled 9-PAHSA. 9-PAHSA is an orally active endogenous GPR120 agonist (EC50=18 μM). 9-PAHSA significantly inhibits LPS-induced inflammatory responses by blocking the NF-κB pathway. 9-PAHSA induces adipocyte browning, enhances glucose uptake and reduces lipid accumulation, while improving mitochondrial function and the survival rate of steatotic hepatocytes. In terms of neuroprotection, 9-PAHSA regulates the expression of REST and BDNF in the prefrontal cortex of diabetic mice, and effectively prevents spatial working memory deficits and abnormal social behaviors. 9-PAHSA does not directly regulate insulin secretion or improve systemic insulin sensitivity, and possesses specific anti-inflammatory, metabolic regulatory and neuroprotective properties. 9-PAHSA can be used in the research of diabetes-related cognitive impairment, obesity and non-alcoholic fatty liver disease .
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- HY-W110705S1
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- HY-153939S
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RG7388-d3-1
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Isotope-Labeled Compounds
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Cancer
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Idasanutlin-d3-1 (RG7388-d3-1) is the deuterium labeled Idasanutlin. Idasanutlin is a potent antagonist of MDM2/p53. Idasanutlin inhibits relapsed or refractory acute myeloid leukemia .
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- HY-P5632
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Bacterial
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Infection
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Bovine tracheal antimicrobial peptide is a kind of comes from the tracheal mucosa of antimicrobial peptides. Bovine tracheal antimicrobial peptide has activity against E.coli D31, K.pneumoniae 13883, S.aureus 25923, P.aeruginosa 27853 and C.albicans 14053, MIC value 12-25, 12-25, 25-50, 25-50, 6-12 μg/ml, respectively .
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- HY-178747S
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9-cis-Octadecenoic acid-d31; 9Z-Octadecenoic acid-d31
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Isotope-Labeled Compounds
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Others
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Oleic acid-d31 (9-cis-Octadecenoic acid-d31) is the deuterium labeled Oleic acid.
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- HY-17007S
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- HY-B0260S6
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- HY-W004295S
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- HY-32351BR
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3-epi-25-hydroxy Cholecalciferol (Standard)
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PTHR
Reference Standards
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Endocrinology
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3-epi-Calcifediol (Standard) is the analytical standard of 3-epi-Calcifediol. This product is intended for research and analytical applications. 3-epi-25-hydroxy Vitamin D3 is the C-3 epimer of 25-hydroxy vitamin D3.1 Dietary administration of 3-epi-25-hydroxy vitamin D3 (0.5 and 1 IU/g) decreases levels of serum parathyroid hormone (PTH) in male, but not female, weanling rats.
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- HY-113424AS1
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1,2-Dioleoyl-sn-glycero-3-phosphocholine-d31
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Isotope-Labeled Compounds
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Others
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DOPC-d31 (1,2-Dioleoyl-sn-glycero-3-phosphocholine-d31) is the deuterium labeled DOPC (HY-113424A). 1,2-Dioleoyl-sn-glycero-3-phosphocholine (DOPC) is a phospholipid and is commonly used alone, or with other components, in the generation of micelles, liposomes, and other types of artificial membranes.
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- HY-RS14242
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Small Interfering RNA (siRNA)
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Others
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TBC1D31 Human Pre-designed siRNA Set A contains three designed siRNAs for TBC1D31 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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TBC1D31 Human Pre-designed siRNA Set A
TBC1D31 Human Pre-designed siRNA Set A
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- HY-145507S
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1-Palmitoyl-2-hydroxy-sn-glycero-3-PG-d31 ammonium; 16:0 Lyso PG-d31 ammonium; PG(16:0/0:0)-d31 ammonium; 1-Hexadecanoyl-sn-glycero-3-phospho-(1'racglycerol)-d31 ammonium
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Isotope-Labeled Compounds
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Metabolic Disease
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1-Palmitoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol)-d31 ammonium (1-Palmitoyl-2-hydroxy-sn-glycero-3-PG-d31 ammonium) is the deuterium labeled 1-Palmitoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol) ammonium (HY-145507). 1-Palmitoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol) (16:0 Lyso PE) sodium is a lysophospholipid containing palmitic acid (16:0) at the sn-1 position. It can be used in the generation of micelles, liposomes, and other types of artificial membranes, including lipid-based drug carrier systems.
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- HY-W009141S
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Glyceryl palmitate-d31
|
Isotope-Labeled Compounds
P-glycoprotein
PI3K
Apoptosis
Caspase
IAP
Akt
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Cancer
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1-Monopalmitin-d31 (Glyceryl palmitate-d31) is the deuterium labeled 1-Monopalmitin (HY-W009141). 1-Monopalmitin (Glyceryl palmitate) is an activator of the PI3K/Akt pathway and an inhibitor of P-glycoprotein (P-gp). 1-Monopalmitin can induce G2/M arrest and caspase-dependent apoptosis in cancer cells, while inhibiting IAPs protein expression. 1-Monopalmitin can increase drug accumulation by inhibiting P-gp activity in intestinal Caco-2 cells. 1-Monopalmitin has the ability to induce protective autophagy and apoptosis of lung cancer cells (IC50=50-58 μg/mL), with low toxicity to normal cells .
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- HY-W127785S
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N,N-Dimethyldodecylamine N-oxide-d31; Dodecyldimethylamine oxide-d31
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Isotope-Labeled Compounds
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Others
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N-Ethyl-N-oxido-dodecan-1-amine-d31 (N,N-Dimethyldodecylamine N-oxide-d31) is the deuterium labeled N-Ethyl-N-oxido-dodecan-1-amine. N-ethyl-N-oxido-dodecan-1-amine is an amine oxide surfactant commonly used as a detergent, emulsifier and wetting agent in various industrial processes, especially in personal care products and household cleaning in the production of agents. N,N-Dimethyldodecylamine N-oxide has unique chemical properties that make it an effective ingredient in many product formulations to help reduce surface tension and enhance cleaning power.
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- HY-W127457S3
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Isotope-Labeled Compounds
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Others
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1,2-Dihexanoyl-sn-glycero-3-phosphocholine-d31 is the deuterium labeled 1,2-Dihexanoyl-sn-glycero-3-phosphocholine. 1,2-Dihexanoyl-sn-glycero-3-phosphocholine is a phosphatidylcholine. It can play a role as a surfactant and is commonly used in the generation of micelles, liposomes, and other types of artificial membranes.
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- HY-141617S1
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Isotope-Labeled Compounds
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Metabolic Disease
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1-Palmitoyl-2-hydroxy-sn-glycero-3-PE-d31 is the deuterium labeled 1-Palmitoyl-2-hydroxy-sn-glycero-3-PE (HY-141617). 1-Palmitoyl-2-hydroxy-sn-glycero-3-PE is a naturally occurring choline phospholipid that can be synthesized from phosphatidylcholine and fatty acids. 1-Palmitoyl-2-hydroxy-sn-glycero-3-PE is used as a structure-related lipid control .
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- HY-90009AS1
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- HY-14281S2
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- HY-151215S
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- HY-10284S3
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- HY-A0043S2
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- HY-15025S2
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UK-92480-d3N-1
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Phosphodiesterase (PDE)
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Cancer
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Sildenafil-d3-1 (UK-92480-d3-1) is deuterium labeled Sildenafil-d3. Sildenafil (UK-92480) is a potent phosphodiesterase type 5 (PDE5) inhibitor with an IC50 of 5.22 nM.
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- HY-109128S2
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MYK-491-d3-1
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Isotope-Labeled Compounds
Myosin
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Cardiovascular Disease
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Danicamtiv-d3-1 (MYK-491-d3-1) is a deuterated labeled Danicamtiv (HY-109128). Danicamtiv (MYK-491), an inotropic agent, is a selective allosteric activator of cardiac myosin. Danicamtiv increases cardiac systolic function and preserves mechanical efficiency .
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- HY-66011AS3
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BAY 12-8039-d3-1
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Isotope-Labeled Compounds
Bacterial
Antibiotic
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Infection
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Moxifloxacin-d3-1 hydrochloride (BAY 12-8039-d3-1) is a deuterium labeled Moxifloxacin (HY-66011A). Moxifloxacin is an orally active 8-methoxyquinolone antimicrobial for use in the treatment of acute bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, and community-acquired pneumonia .
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- HY-W355700S
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Isotope-Labeled Compounds
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Infection
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1-Oleoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine-d31 is the deuterium labeled 1-Oleoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine (HY-W355700). 1-oleoyl-sn-glycero-3-phosphoethanolamine (LysoPE 18:1) is a lysophosphatidylethanolamine molecule involved in phospholipid metabolism, targeting cell membrane receptors (such as G protein-coupled receptors) to regulate cell signaling pathways. 1-oleoyl-sn-glycero-3-phosphoethanolamine may activate mitogen-activated protein kinase (MAPK) signaling, promote cell migration, regulate inflammatory responses and lipid metabolism, and has both pro-inflammatory and anti-inflammatory activities. 1-oleoyl-sn-glycero-3-phosphoethanolamine is mainly used in the screening of biomarkers for metabolic diseases (such as non-alcoholic fatty liver disease and obesity), as well as the study of the mechanism of lysophospholipids in cell membrane homeostasis and signal transduction .
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- HY-W709612
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N-Desmethyl regorafenib N-oxide-d3-1
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Isotope-Labeled Compounds
VEGFR
Raf
c-Kit
Drug Metabolite
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Cancer
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Regorafenib N-oxide and N-desmethyl (M5)-d3-1 (N-Desmethyl regorafenib N-oxide-d3-1) is the deuterium labeled Regorafenib N-oxide and N-desmethyl (M5) (HY-108226). Regorafenib N-oxide and N-desmethyl (M5) (N-Desmethyl regorafenib N-oxide) is an active metabolite of Sorafenib (HY-10201) and can be metabolized by CYP3A4 .
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- HY-B0223S4
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SKF-62979-d3-1
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Reactive Oxygen Species (ROS)
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Cancer
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Albendazole-d3-1 (SKF-62979-d3-1) is the deuterium labeled Albendazole (HY-B0223). Albendazole (SKF-62979) is an orally active and broad-spectrum parasiticide with high effectiveness and low host toxicity, is used for the research of gastrointestinal parasites in humans and animals. Albendazole induces apoptosis and autophagy in cancer cells. Albendazole also inhibits tubulin polymerization and HIF-1α, VEGF expression, has antioxidant activity, and inhibits the glycolytic process in cancer cells .
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- HY-B0740S3
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MK130-d3-1 hydrochloride
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Isotope-Labeled Compounds
5-HT Receptor
Parasite
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Infection
Neurological Disease
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Cyclobenzaprine-d3-1 hydrochloride (MK130-d3-1 hydrochloride) is the deuterium labeled Cyclobenzaprine hydrochloride (HY-B0740). Cyclobenzaprine (MK130) hydrochloride is an orally active 5-HT2 receptor antagonist. Cyclobenzaprine hydrochloride acts centrally, providing skeletal muscle relaxation, alleviating muscle spasms, and reducing pain. Additionally, Cyclobenzaprine hydrochloride has antiprotozoal activity. Additionally, Cyclobenzaprine hydrochloride also possesses antiparasitic activity. Cyclobenzaprine hydrochloride holds promise for research in the fields of acute, painful skeletal muscle disorders and infectious diseases
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- HY-W705192
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Loxoprofen Impurity 31-d3
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Isotope-Labeled Compounds
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Others
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rac trans-loxoprofen alcohol-d3 (Loxoprofen Impurity 31-d3) is the deuterium labeled rac trans-loxoprofen alcohol.
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- HY-W011246S
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HP 029-d3-1; Hydroxytacrine-d3-1 maleate
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Isotope-Labeled Compounds
Cholinesterase (ChE)
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Neurological Disease
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Velnacrine-d3-1 maleate (HP 029-d3-1) is the deuterium labeled Velnacrine maleate (HY-W011246). Velnacrine maleate (HP 029) is an orally active cholinesterase inhibitor that can be used for the research of Alzheimer's disease .
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- HY-W703632
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| Cat. No. |
Product Name |
Target |
Research Area |
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- HY-P5632
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Bacterial
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Infection
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Bovine tracheal antimicrobial peptide is a kind of comes from the tracheal mucosa of antimicrobial peptides. Bovine tracheal antimicrobial peptide has activity against E.coli D31, K.pneumoniae 13883, S.aureus 25923, P.aeruginosa 27853 and C.albicans 14053, MIC value 12-25, 12-25, 25-50, 25-50, 6-12 μg/ml, respectively .
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| Cat. No. |
Product Name |
Chemical Structure |
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- HY-N0830S2
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Palmitic acid-d31 is the deuterium labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. PA can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells .
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- HY-146896S
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16:0-18:1 PA-d31 (sodium) is deuterium labeled 16:0-18:1 PA (sodium).
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- HY-130462S
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1-Palmitoyl-2-oleoyl-sn-glycero-3-PC-d31 is deuterium labeled 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (POPC), a phospholipid, is a major component of biological membranes. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC is used for
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- HY-N0830BS3
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Palmitic acid-d31 (sodium) is the deuterium labeled almitic acid .
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- HY-100354S4
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C16-Ceramide-d31 is deuterium labeled C16-Ceramide.
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- HY-146882S
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1 Publications Verification
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16:0-18:1 PE-d31 is deuterium labeled 16:0-18:1 PE.
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- HY-128922S
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Dexamethasone palmitate-d31 is the deuterium labeled Dexamethasone palmitate(HY-128922).Dexamethasone palmitate (DXP) is a proagent of Dexamethasone (HY-14648). Dexamethasone palmitate can be used for the research of inflammation .
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- HY-125783S1
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1-Palmitoyl-sn-glycero-3-phosphocholine-d31 (16:0 Lyso PC-d31) is deuterium labeled 1-Palmitoyl-sn-glycero-3-phosphocholine (HY-125783). 1-Palmitoyl-sn-glycero-3-phosphocholine (16:0 Lyso PC) is an abundant lysophosphatidylcholine. 1-Palmitoyl-sn-glycero-3-phosphocholine exhibits proinflammatory activity. 1-Palmitoyl-sn-glycero-3-phosphocholine can be used in the study of atherosclerosis .
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- HY-146885S
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1 Publications Verification
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16:0-18:1 PS-d31 (sodium) is deuterium labeled 16:0-18:1 PS (sodium).
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- HY-146877S
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16:0-18:1 PG-d31 is deuterium labeled 16:0-18:1 PG.
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- HY-N1482S1
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Methyl palmitate-d31 is the deuterium labeled Methyl palmitate. Methyl palmitate, an acaricidal compound occurring in green walnut husks, inhibits phagocytic activity and immune response. Methyl palmitate also posseses anti-inflammatory and antifibrotic effects .
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- HY-N2086S
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Ethyl palmitate-d31 is the deuterium labeled Ethyl palmitate. Ethyl palmitate, a fatty acid ethyl ester (FAEE), shows a marked preference for the synthesis of ethyl palmitate and ethyl oleate over other FAEEs in human subjects after ethanol consumption. Ethyl palmitate is used as a hair- and skin-conditioning agent .
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- HY-W013061S2
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Propane-1,2,3-triyl tripalmitate-d31 is the deuterium labeled Propane-1,2,3-triyl tripalmitate (HY-W013061). Propane-1,2,3-triyl tripalmitate is a saturated fat. Propane-1,2,3-triyl tripalmitate enhances the lymphatic transport of Glycerol tristearate (HY-127035) .
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- HY-116193S
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5-PAHSA-d31 is the deuterium labeled 5-PAHSA .
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- HY-W074890S
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Palmitoylglycine-d31 is the deuterium labeled Palmitoylglycine .
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- HY-141629S
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N-Palmitoyl-D-sphingomyelin-d31 is deuterium labeled N-Palmitoyl-D-sphingomyelin.
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- HY-W010708S2
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Cholesteryl palmitate-d31 is deuterium labeled Cholesteryl palmitate. Cholesteryl palmitate is a useful prognostic biomarker for chronic interstitial pneumonia (CIP) .
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- HY-B1465S
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1-Hexadecanol-d31 is the deuterium labeled 1-Hexadecanol . 1-Hexadecanol is a fatty alcohol, a lipophilic substrate .
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- HY-146891S
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16:0-16:0 PC-d31 is deuterium labeled 16:0-16:0 PC.
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- HY-146892S
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1-Palmitoyl-2-palmitoyl-sn-glycero-3-phosphocholine-d31 is deuterium labeled 1-Palmitoyl-2-palmitoyl-sn-glycero-3-phosphocholine.
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- HY-W701599
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Oxiran-2-ylmethyl hexadecanoate-d31 is deuterium labeled Glycidyl palmitate. Glycidyl Palmitate is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
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- HY-146875S
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1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoinositol-d31 (ammonium) is deuterium labeled 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoinositol (ammonium).
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- HY-15592S2
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Cabotegravir d3-1 (GSK-1265744-d3-1) is a deuterium substitute of Cabotegravir. Cabotegravir is a potent HIV integrase inhibitor used in AIDS research
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- HY-W134007S3
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Hexadecanoate-d31 (potassium) is the deuterium labeled Hexadecanoate .
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- HY-120657S1
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9-PAHSA-d31 is the deuterium labeled 9-PAHSA. 9-PAHSA is an orally active endogenous GPR120 agonist (EC50=18 μM). 9-PAHSA significantly inhibits LPS-induced inflammatory responses by blocking the NF-κB pathway. 9-PAHSA induces adipocyte browning, enhances glucose uptake and reduces lipid accumulation, while improving mitochondrial function and the survival rate of steatotic hepatocytes. In terms of neuroprotection, 9-PAHSA regulates the expression of REST and BDNF in the prefrontal cortex of diabetic mice, and effectively prevents spatial working memory deficits and abnormal social behaviors. 9-PAHSA does not directly regulate insulin secretion or improve systemic insulin sensitivity, and possesses specific anti-inflammatory, metabolic regulatory and neuroprotective properties. 9-PAHSA can be used in the research of diabetes-related cognitive impairment, obesity and non-alcoholic fatty liver disease .
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- HY-W110705S1
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1-Bromopentadecane-d31 is the deuterium labeled 1-Bromopentadecane .
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- HY-153939S
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Idasanutlin-d3-1 (RG7388-d3-1) is the deuterium labeled Idasanutlin. Idasanutlin is a potent antagonist of MDM2/p53. Idasanutlin inhibits relapsed or refractory acute myeloid leukemia .
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- HY-178747S
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Oleic acid-d31 (9-cis-Octadecenoic acid-d31) is the deuterium labeled Oleic acid.
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- HY-17007S
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Saquinavir-d9 (Ro 31-8959-d9) is the deuterium labeled Saquinavir (HY-17007). Saquinavir (Ro 31-8959) is an orally active HIV protease inhibitor that can be used in the research of AIDS. Saquinavir also has anti-inflammatory activity and can induce apoptosis of human red blood cells .
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- HY-B0260S6
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Methylprednisolone-d3-1 (U 7532-d3-1) is the deuterium labeled Methylprednisolone (HY-B0260). Methylprednisolone (U 7532) is a synthetic corticosteroid with anti-inflammatory and immunomodulating properties. Methylprednisolone improve severe or critical COVID-19 by activating ACE2 and reducing IL-6 levels .
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- HY-W004295S
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1-Pentadecanol-d31 is the deuterium labeled 1-Pentadecanol . 1-Pentadecanol is a naturally occurring antiacne agent .
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- HY-113424AS1
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DOPC-d31 (1,2-Dioleoyl-sn-glycero-3-phosphocholine-d31) is the deuterium labeled DOPC (HY-113424A). 1,2-Dioleoyl-sn-glycero-3-phosphocholine (DOPC) is a phospholipid and is commonly used alone, or with other components, in the generation of micelles, liposomes, and other types of artificial membranes.
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- HY-145507S
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1-Palmitoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol)-d31 ammonium (1-Palmitoyl-2-hydroxy-sn-glycero-3-PG-d31 ammonium) is the deuterium labeled 1-Palmitoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol) ammonium (HY-145507). 1-Palmitoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol) (16:0 Lyso PE) sodium is a lysophospholipid containing palmitic acid (16:0) at the sn-1 position. It can be used in the generation of micelles, liposomes, and other types of artificial membranes, including lipid-based drug carrier systems.
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- HY-W009141S
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1-Monopalmitin-d31 (Glyceryl palmitate-d31) is the deuterium labeled 1-Monopalmitin (HY-W009141). 1-Monopalmitin (Glyceryl palmitate) is an activator of the PI3K/Akt pathway and an inhibitor of P-glycoprotein (P-gp). 1-Monopalmitin can induce G2/M arrest and caspase-dependent apoptosis in cancer cells, while inhibiting IAPs protein expression. 1-Monopalmitin can increase drug accumulation by inhibiting P-gp activity in intestinal Caco-2 cells. 1-Monopalmitin has the ability to induce protective autophagy and apoptosis of lung cancer cells (IC50=50-58 μg/mL), with low toxicity to normal cells .
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- HY-W127785S
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N-Ethyl-N-oxido-dodecan-1-amine-d31 (N,N-Dimethyldodecylamine N-oxide-d31) is the deuterium labeled N-Ethyl-N-oxido-dodecan-1-amine. N-ethyl-N-oxido-dodecan-1-amine is an amine oxide surfactant commonly used as a detergent, emulsifier and wetting agent in various industrial processes, especially in personal care products and household cleaning in the production of agents. N,N-Dimethyldodecylamine N-oxide has unique chemical properties that make it an effective ingredient in many product formulations to help reduce surface tension and enhance cleaning power.
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- HY-W127457S3
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1,2-Dihexanoyl-sn-glycero-3-phosphocholine-d31 is the deuterium labeled 1,2-Dihexanoyl-sn-glycero-3-phosphocholine. 1,2-Dihexanoyl-sn-glycero-3-phosphocholine is a phosphatidylcholine. It can play a role as a surfactant and is commonly used in the generation of micelles, liposomes, and other types of artificial membranes.
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- HY-141617S1
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1-Palmitoyl-2-hydroxy-sn-glycero-3-PE-d31 is the deuterium labeled 1-Palmitoyl-2-hydroxy-sn-glycero-3-PE (HY-141617). 1-Palmitoyl-2-hydroxy-sn-glycero-3-PE is a naturally occurring choline phospholipid that can be synthesized from phosphatidylcholine and fatty acids. 1-Palmitoyl-2-hydroxy-sn-glycero-3-PE is used as a structure-related lipid control .
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- HY-90009AS1
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Tadalafil- 13C2,d3-1 (IC-351- 13C2,d3-1) is the deuterium and 13C-labeled Tadalafil (HY-90009A). Tadalafil (IC-351) is a PDE5 inhibitor with an IC50 value of 1.8 nM.
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- HY-14281S2
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Trilostane-d3-1 (Win 24540-d3-1) is deuterium-labeled Trilostane (HY-14281) .
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- HY-151215S
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S-Sulfo-DL-cysteine-2,3,3-d3-1 is the deuterium labeled S-Sulfo-DL-cysteine .
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- HY-10284S3
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Linagliptin-d3-1 (BI 1356-d3-1) is the deuterium labeled Linagliptin (HY-10284). Linagliptin is a highly potent, selective DPP-4 inhibitor with IC50 of 1 nM .
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- HY-A0043S2
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Cilazapril-d5 (Ro 31-2848-d5) trifluoroacetate is the deuterium labeled Cilazapril (HY-A0043). Cilazapril is an angiotensin-converting enzyme (ACE) inhibitor used for the study of hypertension and congestive heart failure.
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- HY-15025S2
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Sildenafil-d3-1 (UK-92480-d3-1) is deuterium labeled Sildenafil-d3. Sildenafil (UK-92480) is a potent phosphodiesterase type 5 (PDE5) inhibitor with an IC50 of 5.22 nM.
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- HY-109128S2
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Danicamtiv-d3-1 (MYK-491-d3-1) is a deuterated labeled Danicamtiv (HY-109128). Danicamtiv (MYK-491), an inotropic agent, is a selective allosteric activator of cardiac myosin. Danicamtiv increases cardiac systolic function and preserves mechanical efficiency .
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- HY-66011AS3
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Moxifloxacin-d3-1 hydrochloride (BAY 12-8039-d3-1) is a deuterium labeled Moxifloxacin (HY-66011A). Moxifloxacin is an orally active 8-methoxyquinolone antimicrobial for use in the treatment of acute bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, and community-acquired pneumonia .
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- HY-W355700S
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1-Oleoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine-d31 is the deuterium labeled 1-Oleoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine (HY-W355700). 1-oleoyl-sn-glycero-3-phosphoethanolamine (LysoPE 18:1) is a lysophosphatidylethanolamine molecule involved in phospholipid metabolism, targeting cell membrane receptors (such as G protein-coupled receptors) to regulate cell signaling pathways. 1-oleoyl-sn-glycero-3-phosphoethanolamine may activate mitogen-activated protein kinase (MAPK) signaling, promote cell migration, regulate inflammatory responses and lipid metabolism, and has both pro-inflammatory and anti-inflammatory activities. 1-oleoyl-sn-glycero-3-phosphoethanolamine is mainly used in the screening of biomarkers for metabolic diseases (such as non-alcoholic fatty liver disease and obesity), as well as the study of the mechanism of lysophospholipids in cell membrane homeostasis and signal transduction .
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- HY-W709612
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Regorafenib N-oxide and N-desmethyl (M5)-d3-1 (N-Desmethyl regorafenib N-oxide-d3-1) is the deuterium labeled Regorafenib N-oxide and N-desmethyl (M5) (HY-108226). Regorafenib N-oxide and N-desmethyl (M5) (N-Desmethyl regorafenib N-oxide) is an active metabolite of Sorafenib (HY-10201) and can be metabolized by CYP3A4 .
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- HY-B0223S4
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Albendazole-d3-1 (SKF-62979-d3-1) is the deuterium labeled Albendazole (HY-B0223). Albendazole (SKF-62979) is an orally active and broad-spectrum parasiticide with high effectiveness and low host toxicity, is used for the research of gastrointestinal parasites in humans and animals. Albendazole induces apoptosis and autophagy in cancer cells. Albendazole also inhibits tubulin polymerization and HIF-1α, VEGF expression, has antioxidant activity, and inhibits the glycolytic process in cancer cells .
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- HY-B0740S3
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Cyclobenzaprine-d3-1 hydrochloride (MK130-d3-1 hydrochloride) is the deuterium labeled Cyclobenzaprine hydrochloride (HY-B0740). Cyclobenzaprine (MK130) hydrochloride is an orally active 5-HT2 receptor antagonist. Cyclobenzaprine hydrochloride acts centrally, providing skeletal muscle relaxation, alleviating muscle spasms, and reducing pain. Additionally, Cyclobenzaprine hydrochloride has antiprotozoal activity. Additionally, Cyclobenzaprine hydrochloride also possesses antiparasitic activity. Cyclobenzaprine hydrochloride holds promise for research in the fields of acute, painful skeletal muscle disorders and infectious diseases
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- HY-W705192
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rac trans-loxoprofen alcohol-d3 (Loxoprofen Impurity 31-d3) is the deuterium labeled rac trans-loxoprofen alcohol.
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- HY-W011246S
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Velnacrine-d3-1 maleate (HP 029-d3-1) is the deuterium labeled Velnacrine maleate (HY-W011246). Velnacrine maleate (HP 029) is an orally active cholinesterase inhibitor that can be used for the research of Alzheimer's disease .
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- HY-W703632
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2-(4-Isobutylphenyl)propan-3,3,3-d3-1-ol is the deuterium labeled Ibuprofen alcohol (HY-131261). Ibuprofen alcohol, a nonsteroidal antiinflammatory agent (NSAID), exhibits very little activity for acid-sensing ion channels (ASICs) .
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- HY-RS14242
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siRNAs
Human Pre-designed siRNA Sets
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TBC1D31 Human Pre-designed siRNA Set A contains three designed siRNAs for TBC1D31 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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