Regorafenib N-oxide and N-desmethyl (M5)-d3-1
Regorafenib N-oxide and N-desmethyl (M5)-d3-1 (N-Desmethyl regorafenib N-oxide-d3-1) is the deuterium labeled Regorafenib N-oxide and N-desmethyl (M5) (HY-108226). Regorafenib N-oxide and N-desmethyl (M5) (N-Desmethyl regorafenib N-oxide) is an active metabolite of Sorafenib (HY-10201) and can be metabolized by CYP3A4.
For research use only. We do not sell to patients.
- Formula: C20H10D3ClF4N4O4
- Molecular Weight:487.81
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Biological Activity
Description
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled CAS 835621-12-0
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Molecular Weight 487.81
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Formula C20H10D3ClF4N4O4
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SMILES
O=C(NC1=CC=C(Cl)C(C(F)(F)F)=C1)NC2=C(F)C([2H])=C(OC3=CC=N(C(C(N)=O)=C3)=O)C([2H])=C2[2H]
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Synonyms
N-Desmethyl regorafenib N-oxide-d3-1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Regorafenib N-oxide and N-desmethyl (M5)-d3-1 Related Classifications
HY-W709612 Related Classifications
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