Tadalafil-13C2,d3-1
Tadalafil-13C2,d3-1 (IC-351-13C2,d3-1) is the deuterium and 13C-labeled Tadalafil (HY-90009A). Tadalafil (IC-351) is a PDE5 inhibitor with an IC50 value of 1.8 nM.
For research use only. We do not sell to patients.
- Formula: C2013C2H14D3N3O4
- Molecular Weight:392.39
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
-
Unlabeled Cas 171596-29-5
-
Molecular Weight 392.39
-
Formula C2013C2H14D3N3O4
-
SMILES
O=C(N([13C]1)C([2H])([2H])[2H])[C@]2(CC3=C(NC4=C3C=CC=C4)[C@H](N2[13C]1=O)C5=CC=C6OCOC6=C5)[H]
-
Synonyms
IC-351-13C2,d3
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)