30 Results for "

Tolterodine

" in MedChemExpress (MCE) Product Catalog:
Products (30)

30 Results for "Tolterodine" in MCE Product Catalog:

Cat. No.: HY-A0024
CAS No.: 124937-51-5
Synonyms: (R)-(+)-Tolterodine; (+)-Tolterodine; (R)-Tolterodine; PNU-200583
Target:  

mAChR Cytochrome P450

Research Areas:  

Neurological Disease Cancer

Tolterodine ((R)-(+)-Tolterodine) is a mAChR inhibitor and substrate for cytochrome P450 enzymes. Tolterodine competitively binds acetylcholine, reduces sympathetic excitation, and inhibits involuntary bladder muscle contraction. Tolterodine restores the Nrf2/NF-κB signaling pathway, mediates protection against inflammatory response and ferroptosis. Tolterodine ameliorates LPS (HY-D1056)-induced reactive oxygen species production and lipid oxidation. Tolterodine can be used for the research of urinary tract infections and overactive bladder .
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1 Cited Publications
Cat. No.: HY-76569
CAS No.: 207679-81-0
Synonyms: PNU-200577; 5-Hydroxymethyl Tolterodine
Target:  

mAChR

Research Areas:  

Neurological Disease Cancer

Desfesoterodine (PNU-200577) is a potent and selective muscarinic receptor (mAChR) antagonist with a KB and a pA2 of 0.84 nM and 9.14, respectively . Desfesoterodine is a major pharmacologically active metabolite of Tolterodine (PNU-200583; HY-A0024) and Fesoterodine (HY-70053) . Desfesoterodine improves cerebral infarction induced detrusor overactivity in rats .
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Cat. No.: HY-90010
CAS No.: 124937-52-6
Synonyms: Kabi-2234; PNU-200583E
Target:  

mAChR Cytochrome P450

Research Areas:  

Neurological Disease Cancer

Tolterodine tartrate (Kabi-2234) is a mAChR inhibitor and substrate for cytochrome P450 enzymes. Tolterodine tartrate competitively binds acetylcholine, reduces sympathetic excitation, and inhibits involuntary bladder muscle contraction. Tolterodine tartrate restores the Nrf2/NF-κB signaling pathway, mediates protection against inflammatory response and ferroptosis. Tolterodine tartrate ameliorates LPS (HY-D1056)-induced reactive oxygen species production and lipid oxidation. Tolterodine tartrate can be used for the research of urinary tract infections and overactive bladder .
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Cat. No.: HY-76570
CAS No.: 200801-70-3
Synonyms: (Rac)-Desfesoterodine; (Rac)-PNU-200577
Target:  

mAChR

Research Areas:  

Neurological Disease

(Rac)-5-Hydroxymethyl Tolterodine ((Rac)-Desfesoterodine), an active metabolite of Tolterodine, is a mAChR antagonist (Ki values of 2.3 nM, 2 nM, 2.5 nM, 2.8 nM, and 2.9 nM for M1, M2, M3, M4, and M5 receptors, respectively). (Rac)-5-Hydroxymethyl Tolterodine can be used for overactive bladder research .
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Cat. No.: HY-76996
CAS No.: 260389-90-0
Target:  

Drug Intermediate

Research Areas:  

Others

Tolterodine impurity 1 is an impurity of Tolterodine (HY-A0024).
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Cat. No.: HY-76569R
CAS No.: 207679-81-0
Synonyms: PNU-200577 (Standard); 5-Hydroxymethyl Tolterodine (Standard)
Research Areas:  

Neurological Disease

Desfesoterodine (Standard) is the analytical standard of Desfesoterodine. This product is intended for research and analytical applications. Desfesoterodine (PNU-200577) is a potent and selective muscarinic receptor (mAChR) antagonist with a KB and a pA2 of 0.84 nM and 9.14, respectively . Desfesoterodine is a major pharmacologically active metabolite of Tolterodine (PNU-200583; HY-A0024) and Fesoterodine (HY-70053) . Desfesoterodine improves cerebral infarction induced detrusor overactivity in rats .
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Cat. No.: HY-76570A
CAS No.: 250214-40-5
Synonyms: (Rac)-Desfesoterodine hydrochloride; (Rac)-PNU-200577 hydrochloride
Target:  

mAChR

Research Areas:  

Neurological Disease

(Rac)-5-Hydroxymethyl Tolterodine ((Rac)-Desfesoterodine) hydrochloride, an active metabolite of Tolterodine, is a mAChR antagonist (Ki values of 2.3 nM, 2 nM, 2.5 nM, 2.8 nM, and 2.9 nM for M1, M2, M3, M4, and M5 receptors, respectively). (Rac)-5-Hydroxymethyl Tolterodine hydrochloride can be used for overactive bladder research .
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Cat. No.: HY-A0024R
CAS No.: 124937-51-5
Synonyms: (R)-(+)-Tolterodine (Standard); (+)-Tolterodine (Standard); (R)-Tolterodine (Standard); PNU-200583 (Standard)
Tolterodine (Standard) is the analytical standard of Tolterodine. This product is intended for research and analytical applications. Tolterodine ((R)-(+)-Tolterodine) is a mAChR inhibitor and substrate for cytochrome P450 enzymes. Tolterodine competitively binds acetylcholine, reduces sympathetic excitation, and inhibits involuntary bladder muscle contraction. Tolterodine restores the Nrf2/NF-κB signaling pathway, mediates protection against inflammatory response and ferroptosis. Tolterodine ameliorates LPS (HY-D1056)-induced reactive oxygen species production and lipid oxidation. Tolterodine can be used for the research of urinary tract infections and overactive bladder.
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Cat. No.: HY-A0024S
CAS No.: 1217645-16-3
Synonyms: (R)-(+)-Tolterodine-d14 hydrochloride; (+)-Tolterodine-d14 hydrochloride; (R)-Tolterodine-d14 hydrochloride; PNU-200583-d14 hydrochloride
Tolterodine-d14 (hydrochloride) is the deuterium labeled Tolterodine hydrochloride . Tolterodine ((R)-(+)-Tolterodine) is a mAChR inhibitor and substrate for cytochrome P450 enzymes. Tolterodine competitively binds acetylcholine, reduces sympathetic excitation, and inhibits involuntary bladder muscle contraction. Tolterodine restores the Nrf2/NF-κB signaling pathway, mediates protection against inflammatory response and ferroptosis. Tolterodine ameliorates LPS (HY-D1056)-induced reactive oxygen species production and lipid oxidation. Tolterodine can be used for the research of urinary tract infections and overactive bladder.
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Cat. No.: HY-W708197
CAS No.: 854306-72-2
Target:  

mAChR

Research Areas:  

Neurological Disease

Tolterodine dimer is the impurity of Tolterodine (HY-A0024). Tolterodine is a potent muscarinic receptor antagonist.
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Cat. No.: HY-A0024AS1
CAS No.: 2747918-62-1
(Rac)-Tolterodine-d5 is deuterium labeled (rac)-Tolterodine.
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Cat. No.: HY-132645S
CAS No.: 1246816-99-8
(Rac)-Tolterodine-d14 (hydrochloride) is the deuterium labeled (Rac)-Tolterodine hydrochloride .
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Cat. No.: HY-W704036
CAS No.: 1794768-30-1
Synonyms: rac Desisopropyl Tolterodine methyl ether-d7
Tolterodine Ep Impurity D-d7 (rac Desisopropyl tolterodine methyl ether-d7) is the deuterium labeled Tolterodine Ep Impurity D (HY-Z12547).
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Cat. No.: HY-132636S
CAS No.: 1189681-84-2
(Rac)-5-Carboxy Tolterodine-d14 is the deuterium labeled (Rac)-5-Carboxy Tolterodine .
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Cat. No.: HY-W703068
CAS No.: 1346600-20-1
Rac desisopropyl tolterodine-d7 is the deuterium labeled 2-(3-(Isopropylamino)-1-phenylpropyl)-4-methylphenol (Tolterodine Impurity) (HY-Z8824).
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Cat. No.: HY-76570S1
5-Hydroxymethyl Tolterodine-d14 (formate) is deuterium labeled (Rac)-5-Hydroxymethyl Tolterodine. (Rac)-5-Hydroxymethyl Tolterodine ((Rac)-Desfesoterodine), an active metabolite of Tolterodine, is a mAChR antagonist (Ki values of 2.3 nM, 2 nM, 2.5 nM, 2.8 nM, and 2.9 nM for M1, M2, M3, M4, and M5 receptors, respectively). (Rac)-5-Hydroxymethyl Tolterodine can be used for overactive bladder research .
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Cat. No.: HY-W700319
CAS No.: 1076199-77-3
Target:  

mAChR

Research Areas:  

Neurological Disease

(Rac)-5-Carboxy tolterodine is an inactive metabolite of the muscarinic acetylcholine receptor antagonist Tolterodine (HY-A0024).
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Cat. No.: HY-132353S
CAS No.: 1189868-60-7
(Rac)-5-Carboxy desisopropyl tolterodine-d7 is the deuterium labeled (Rac)-5-Carboxy desisopropyl tolterodine .
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Cat. No.: HY-76569S1
CAS No.: 1191280-58-6
Synonyms: PNU-200577-d14; 5-Hydroxymethyl Tolterodine-d14
(R)-Hydroxytolterodine-d14 is deuterated labeled Desfesoterodine (HY-76569). Desfesoterodine (PNU-200577) is a potent and selective muscarinic receptor (mAChR) antagonist with a KB and a pA2 of 0.84 nM and 9.14, respectively . Desfesoterodine is a major pharmacologically active metabolite of Tolterodine (PNU-200583; HY-A0024) and Fesoterodine (HY-70053) . Desfesoterodine improves cerebral infarction induced detrusor overactivity in rats .
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