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Results for "

anti-stress

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adrenergic Receptor (1) Apoptosis (3) Bacterial (2) Endogenous Metabolite (9) GABA Receptor (1) iGluR (1) mGluR (1) Reactive Oxygen Species (1)
By Research Areas:	Cancer (3) Cardiovascular Disease (1) Infection (1) Inflammation/Immunology (1) Neurological Disease (13)

Inhibitors & Agonists

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0368

Linalool 1 Publications Verification	Apoptosis iGluR Endogenous Metabolite Bacterial	Infection Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
Linalool is a natural monoterpene which is a competitive NMDA receptor antagonist. Linalool is orally active and crosses the blood-brain barrier. Linalool has anticancer, antibacterial, anti-inflammatory, neuroprotective, anxiolytic, antidepressant, anti-stress, cardioprotective, hepatoprotective, nephroprotective and pulmonary protective activities .

HY-111191

ONO-2952	Adrenergic Receptor	Neurological Disease
ONO-2952 is a potent, selective and orally active translocator protein 18 kDa (TSPO) antagonist with K_i of 0.33-9.30 nM for rat and human TSPO. ONO-2952 is more selective for TSPO than other receptors, transporters, ion channels and enzymes. ONO-2952 exerts its anti-stress effects through inhibition of excessive activation of noradrenergic system in the brain without the amnesic effect. ONO-2952 has the potential for irritable bowel syndrome treatment .

HY-W012123

3,4,5-Trimethoxycinnamic acid	GABA Receptor Endogenous Metabolite	Neurological Disease
3,4,5-Trimethoxycinnamic acid is a phenylpropanoid isolated from the roots of Polygala tenuifolia WILLD, with anti-stress effect, prolonging the sleeping time in animals . 3,4,5-Trimethoxycinnamic acid increases expression of GAD65 and γ-subunit of GABAA receptor, but shows no effect on the amounts of α-, β-subunits .

HY-108059

β-Cryptoxanthin (3R)-β-Cryptoxanthin	Endogenous Metabolite	Neurological Disease
β-Cryptoxanthin ((3R)-β-Cryptoxanthin), isolated from tangerines, red peppers, and pumpkin, is an oxygenated carotenoid and a potent antioxidant. β-Cryptoxanthin has an anti-stress effect .

HY-110146

XAP044	mGluR	Neurological Disease
XAP044 is a potent and selective antagonist of mGlu7. The metabotropic glutamate receptor subtype 7 (mGlu7) is an important presynaptic regulator of neurotransmission in the mammalian CNS. XAP044 demonstrates good brain exposure and wide spectrum anti-stress and antidepressant- and anxiolytic-like efficacy in rodent behavioral paradigms .

HY-15121S

L-Theanine-d5 L-Glutamic Acid γ-ethyl amide-d₅; Nγ-Ethyl-L-glutamine-d₅	Apoptosis Endogenous Metabolite	Neurological Disease
L-Theanine-d₅ is the deuterium labeled L-Theanine. L-Theanine (L-Glutamic Acid γ-ethyl amide）is a non-protein amino acid contained in green tea leaves, which blocks the binding of L-glutamic acid to glutamate receptors in the brain, and with neuroprotective and anti-oxidative activities. L-Theanine causes anti-stress effects via the inhibition of cortical neuron excitation by oral intake[1][2][3].

HY-N5113

6α-Chloro-5β-hydroxywithaferin A	Bacterial	Others
6α-Chloro-5β-hydroxywithaferin A is a withanolide that can be isolated from W. somnifera. W. somnifera has antioxidant, anti-inflammatory, immunomodulatory, anticarcinogenic, antibacterial antiparkinsonism and antistress properties .

HY-B0762

Acetyl-L-carnitine hydrochloride 2 Publications Verification O-Acetyl-L-carnitine hydrochloride; ALCAR hydrochloride	Endogenous Metabolite	Neurological Disease
Acetyl-L-carnitine (O-Acetyl-L-carnitine) hydrochloride is a blood-brain permeable acetyl ester of the amino acid L-carnitine found in the body. Acetyl-L-carnitine hydrochloride is often used as a dietary supplement, and exibits anti-stress-related psychiatric disorders .

HY-15121

L-Theanine 1 Publications Verification L-Glutamic Acid γ-ethyl amide; Nγ-Ethyl-L-glutamine	Apoptosis Endogenous Metabolite Reactive Oxygen Species	Neurological Disease Cancer
L-Theanine (L-Glutamic Acid γ-ethyl amide) is a non-protein amino acid contained in green tea leaves, which blocks the binding of L-glutamic acid to glutamate receptors in the brain, and with neuroprotective, anticancer and anti-oxidative activities. L-Theanine can pass through the blood–brain barrier and is orally active .

HY-N12715

Valerena-4,7(11)-diene	Others	Neurological Disease
Valerena-4,7(11)-diene is a tranquilizer. Valerena-4,7(11)-diene suppresses stress-induced excitatory behaviors. Valerena-4,7(11)-diene is expressed via olfactory stimulation and pulmonary absorption .

HY-N1440

Koumine
Koumine is an alkaloid separated from Gelsemium elegans, shows potent anti-tumor activity. Koumine up-regulates the Bax/Bcl-2 ratio and caspase-3 expression in human breast cancer cells . Koumine has anxiolytic, antistress, antipsoriatic, and analgesic activities , protects against the development of arthritis in Rheumatoid arthritis (RA) animal models .

HY-B0762S

Acetyl-L-carnitine-d3 hydrochloride O-Acetyl-L-carnitine-d₃ (hydrochloride)	Endogenous Metabolite	Neurological Disease
Acetyl-L-carnitine-d₃ (hydrochloride) is the deuterium labeled Acetyl-L-carnitine hydrochloride. Acetyl-L-carnitine hydrochloride is a blood-brain permeable acetyl ester of the amino acid L-carnitine found in the body. Acetyl-L-carnitine hydrochloride is often used as a dietary supplement, and exibits anti-stress-related psychiatric disorders[1].

HY-B0762S1

Acetyl-L-carnitine-d3-1 hydrochloride O-Acetyl-L-carnitine-d₃-1 (hydrochloride)	Endogenous Metabolite	Neurological Disease
Acetyl-L-carnitine-d₃-1 (hydrochloride) is the deuterium labeled Acetyl-L-carnitine hydrochloride. Acetyl-L-carnitine hydrochloride is a blood-brain permeable acetyl ester of the amino acid L-carnitine found in the body. Acetyl-L-carnitine hydrochloride is often used as a dietary supplement, and exibits anti-stress-related psychiatric disorders[1].

HY-B0762R

Acetyl-L-carnitine hydrochloride (Standard) O-Acetyl-L-carnitine hydrochloride (Standard); ALCAR hydrochloride (Standard)	Endogenous Metabolite	Neurological Disease Cancer
Acetyl-L-carnitine (hydrochloride) (Standard) is the analytical standard of Acetyl-L-carnitine (hydrochloride). This product is intended for research and analytical applications. Acetyl-L-carnitine (O-Acetyl-L-carnitine) hydrochloride is a blood-brain permeable acetyl ester of the amino acid L-carnitine found in the body. Acetyl-L-carnitine hydrochloride is often used as a dietary supplement, and exibits anti-stress-related psychiatric disorders .

Selank diacetate Selanc diacetate; TP-7 diacetate	Peptides	Neurological Disease
Selank (Selanc) acetate is a synthetic peptide derived from tuftsin. Selank acetate has anxiolytic activity, and is a nootropic, neuropsychotropic, antidepressant, and antistress compound .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0368

Linalool 1 Publications Verification	Cardiovascular Disease Structural Classification Other Monoterpenes Scutellaria indica L. Microorganisms Classification of Application Fields Terpenoids Source classification Umbelliferae Plants Endogenous metabolite Disease Research Fields	Apoptosis iGluR Endogenous Metabolite Bacterial
Linalool is a natural monoterpene which is a competitive NMDA receptor antagonist. Linalool is orally active and crosses the blood-brain barrier. Linalool has anticancer, antibacterial, anti-inflammatory, neuroprotective, anxiolytic, antidepressant, anti-stress, cardioprotective, hepatoprotective, nephroprotective and pulmonary protective activities .

HY-W012123

3,4,5-Trimethoxycinnamic acid	Simple Phenylpropanols Source classification Polygalaceae Phenylpropanoids Plants Endogenous metabolite Polygala tenuifolia Willd.	GABA Receptor Endogenous Metabolite
3,4,5-Trimethoxycinnamic acid is a phenylpropanoid isolated from the roots of Polygala tenuifolia WILLD, with anti-stress effect, prolonging the sleeping time in animals . 3,4,5-Trimethoxycinnamic acid increases expression of GAD65 and γ-subunit of GABAA receptor, but shows no effect on the amounts of α-, β-subunits .

HY-B0762

Acetyl-L-carnitine hydrochloride 2 Publications Verification O-Acetyl-L-carnitine hydrochloride; ALCAR hydrochloride	Alkaloids Source classification Endogenous metabolite	Endogenous Metabolite
Acetyl-L-carnitine (O-Acetyl-L-carnitine) hydrochloride is a blood-brain permeable acetyl ester of the amino acid L-carnitine found in the body. Acetyl-L-carnitine hydrochloride is often used as a dietary supplement, and exibits anti-stress-related psychiatric disorders .

HY-108059

β-Cryptoxanthin (3R)-β-Cryptoxanthin	Other Terpenoids Structural Classification Capsicum annuum L. other families Neurological Disease Classification of Application Fields Terpenoids Source classification Plants Solanaceae Endogenous metabolite Disease Research Fields	Endogenous Metabolite
β-Cryptoxanthin ((3R)-β-Cryptoxanthin), isolated from tangerines, red peppers, and pumpkin, is an oxygenated carotenoid and a potent antioxidant. β-Cryptoxanthin has an anti-stress effect .

HY-N5113

6α-Chloro-5β-hydroxywithaferin A	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Withania somnifera Plants Solanaceae Disease Research Fields	Bacterial
6α-Chloro-5β-hydroxywithaferin A is a withanolide that can be isolated from W. somnifera. W. somnifera has antioxidant, anti-inflammatory, immunomodulatory, anticarcinogenic, antibacterial antiparkinsonism and antistress properties .

HY-15121

L-Theanine 1 Publications Verification L-Glutamic Acid γ-ethyl amide; Nγ-Ethyl-L-glutamine	Structural Classification Microorganisms Neurological Disease Classification of Application Fields Anti-aging Source classification Amino acids Plants Camellia sinensis (L.) O. Ktze. Disease Research Fields Theaceae	Apoptosis Endogenous Metabolite Reactive Oxygen Species
L-Theanine (L-Glutamic Acid γ-ethyl amide) is a non-protein amino acid contained in green tea leaves, which blocks the binding of L-glutamic acid to glutamate receptors in the brain, and with neuroprotective, anticancer and anti-oxidative activities. L-Theanine can pass through the blood–brain barrier and is orally active .

HY-N12715

Valerena-4,7(11)-diene	Structural Classification Terpenoids Sesquiterpenes Source classification Nardostachys jatamansi (D. Don) DC. Plants Valerianaceae	Others
Valerena-4,7(11)-diene is a tranquilizer. Valerena-4,7(11)-diene suppresses stress-induced excitatory behaviors. Valerena-4,7(11)-diene is expressed via olfactory stimulation and pulmonary absorption .

HY-B0762R

Acetyl-L-carnitine hydrochloride (Standard) O-Acetyl-L-carnitine hydrochloride (Standard); ALCAR hydrochloride (Standard)	Structural Classification Alkaloids Source classification Endogenous metabolite	Endogenous Metabolite
Acetyl-L-carnitine (hydrochloride) (Standard) is the analytical standard of Acetyl-L-carnitine (hydrochloride). This product is intended for research and analytical applications. Acetyl-L-carnitine (O-Acetyl-L-carnitine) hydrochloride is a blood-brain permeable acetyl ester of the amino acid L-carnitine found in the body. Acetyl-L-carnitine hydrochloride is often used as a dietary supplement, and exibits anti-stress-related psychiatric disorders .

Cat. No.	Product Name	Chemical Structure

HY-15121S

L-Theanine-d5
L-Theanine-d₅ is the deuterium labeled L-Theanine. L-Theanine (L-Glutamic Acid γ-ethyl amide）is a non-protein amino acid contained in green tea leaves, which blocks the binding of L-glutamic acid to glutamate receptors in the brain, and with neuroprotective and anti-oxidative activities. L-Theanine causes anti-stress effects via the inhibition of cortical neuron excitation by oral intake[1][2][3].

L-Theanine-d5

L-Theanine-d₅ is the deuterium labeled L-Theanine. L-Theanine (L-Glutamic Acid γ-ethyl amide）is a non-protein amino acid contained in green tea leaves, which blocks the binding of L-glutamic acid to glutamate receptors in the brain, and with neuroprotective and anti-oxidative activities. L-Theanine causes anti-stress effects via the inhibition of cortical neuron excitation by oral intake[1][2][3].

HY-B0762S

Acetyl-L-carnitine-d3 hydrochloride
Acetyl-L-carnitine-d₃ (hydrochloride) is the deuterium labeled Acetyl-L-carnitine hydrochloride. Acetyl-L-carnitine hydrochloride is a blood-brain permeable acetyl ester of the amino acid L-carnitine found in the body. Acetyl-L-carnitine hydrochloride is often used as a dietary supplement, and exibits anti-stress-related psychiatric disorders[1].

HY-B0762S1

Acetyl-L-carnitine-d3-1 hydrochloride
Acetyl-L-carnitine-d₃-1 (hydrochloride) is the deuterium labeled Acetyl-L-carnitine hydrochloride. Acetyl-L-carnitine hydrochloride is a blood-brain permeable acetyl ester of the amino acid L-carnitine found in the body. Acetyl-L-carnitine hydrochloride is often used as a dietary supplement, and exibits anti-stress-related psychiatric disorders[1].

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anti-stress

Inhibitors & Agonists

Peptides

NaturalProducts

Isotope-Labeled Compounds

Natural
Products