1. GPCR/G Protein Neuronal Signaling
  2. mGluR
  3. XAP044

XAP044 

Cat. No.: HY-110146
Handling Instructions

XAP044 is a potent and selective antagonist of mGlu7. The metabotropic glutamate receptor subtype 7 (mGlu7) is an important presynaptic regulator of neurotransmission in the mammalian CNS. XAP044 demonstrates good brain exposure and wide spectrum anti-stress and antidepressant- and anxiolytic-like efficacy in rodent behavioral paradigms.

For research use only. We do not sell to patients.

XAP044 Chemical Structure

XAP044 Chemical Structure

CAS No. : 196928-50-4

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Description

XAP044 is a potent and selective antagonist of mGlu7. The metabotropic glutamate receptor subtype 7 (mGlu7) is an important presynaptic regulator of neurotransmission in the mammalian CNS. XAP044 demonstrates good brain exposure and wide spectrum anti-stress and antidepressant- and anxiolytic-like efficacy in rodent behavioral paradigms[1].

Molecular Weight

380.13

Formula

C15H9IO4

CAS No.
SMILES

O=C1C2=CC=C(O)C=C2OC=C1OC3=CC=C(I)C=C3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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XAP044 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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XAP044
Cat. No.:
HY-110146
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