196928-50-4
196928-50-4
Chemical Structure
XAP044
- CAS No.: 196928-50-4
- Formula:C15H9IO4
- Molecular Weight:380.13
IUPAC Name: 7-hydroxy-3-(4-iodophenoxy)-4H-chromen-4-one
InChIKey: XXZKJJYWINSUMJ-UHFFFAOYSA-N
SMILES: O=C1C2=CC=C(O)C=C2OC=C1OC3=CC=C(I)C=C3
Biological Activity: XAP044 is a potent and selective antagonist of mGlu7. The metabotropic glutamate receptor subtype 7 (mGlu7) is an important presynaptic regulator of neurotransmission in the mammalian CNS. XAP044 demonstrates good brain exposure and wide spectrum anti-stress and antidepressant- and anxiolytic-like efficacy in rodent behavioral paradigms[1].
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XAP044 | 99.99% | XAP044 is a potent and selective antagonist of mGlu7. The metabotropic glutamate receptor subtype 7 (mGlu7) is an important presynaptic regulator of neurotransmission in the mammalian CNS. XAP044 demonstrates good brain exposure and wide spectrum anti-stress and antidepressant- and anxiolytic-like efficacy in rodent behavioral paradigms. | ||||||||||||||||||||
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References
Keywords
