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Results for "

antileukemic and antiviral activities

" in MedChemExpress (MCE) Product Catalog:

5

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1

Natural
Products

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N0838
    Cephalotaxine
    1 Publications Verification

    (-)-Cephalotaxine; ZINC19795976

    		 Flavivirus Infection Cancer
    Cephalotaxlen ((-)-Cephalotaxine) is an alkaloid that can be isolated from Cephalotaxus fortunei, with antileukemic and antiviral activities. Cephalotaxlen has anti-ZIKV (Zika virus) activity .
    Cephalotaxine
  • HY-173189A
    2-5A pentasodium solution (100 mM)

    2′,5′-ApApA pentasodium; 2′,5′-trioligoadenylate pentasodium; 5'-O-Triphosphoryladenylyl-(2'→5')-adenylyl-(2'→5')-adenosine pentasodium

    		 RSV DNA/RNA Synthesis Infection Cancer
    2-5A (2′,5′-ApApA) pentasodium solution 100 mM is a high-affinity (Ka=0.04 nM) RNase L binder. 2-5A pentasodium solution 100 mM activates the nuclease activity of latent RNase L to cleave single-stranded RNA by inducing conformational changes and dimerization of latent RNase L, thereby mediating critical antiviral responses and enhancing interferon effects. 2-5A pentasodium solution 100 mM not only effectively inhibits Rauscher murine leukemia virus replication, reduces viremia and splenomegaly, but also enhances antileukemic efficacy when combined with amphotericin B and exhibits favorable high-dose tolerance. 2-5A pentasodium solution 100 mM is an important tool molecule for investigating the pathological mechanisms of viral infection, hereditary prostate cancer and leukemia .
    2-5A pentasodium solution (100 mM)
  • HY-123523
    Enocitabine

    		Nucleoside Antimetabolite/Analog DNA/RNA Synthesis CMV Infection Cancer
    Enocitabine is a nucleoside analog, and is a potent DNA replication inhibitor, and a DNA chain terminator. Enocitabine inhibits the replication of human cytomegalovirus. Enocitabine has antileukemic and antiviral activities .
    Enocitabine
  • HY-107338
    Denotivir

    Vratizolin; Wratizolin

    		 VZV HSV Interleukin Related Infection Inflammation/Immunology Cancer
    Denotivir (Vratizolin) is an orally active antiviral agent for herpes simplex virus (HSV) and varicella-zoster virus (VZV). Denotivir inhibits the proliferation of various cancer cells, and exhibits anti-leukemic activity. Denotivir inhibits the generation of TNF-α, IL-1 and IL-6, exhibits immunosuppressive efficacy .
    Denotivir
  • HY-174816
    DHODH-IN-28

    		Fluorescent Dye Dihydroorotate Dehydrogenase Infection Cancer
    DHODH-IN-28 (Compound 11a) is a potent fluorescent inhibitor targeting human dihydroorotate dehydrogenase (hDHODH) with an IC50 value of 170 nM. DHODH-IN-28 exhibits antileukemic and antiviral activities. DHODH-IN-28 is promising for research of cancers and infectious diseases .
    DHODH-IN-28

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