1. Anti-infection
  2. Influenza Virus
  3. Cephalotaxine

Cephalotaxine (Synonyms: (-)-Cephalotaxine; ZINC19795976)

Cat. No.: HY-N0838 Purity: ≥98.0%
Handling Instructions

Cephalotaxlen ((-)-Cephalotaxine) is an alkaloid that can be isolated from Cephalotaxus drupacea, with antileukemic and antiviral activities. Cephalotaxlen has anti-ZIKV (Zika virus) activity.

For research use only. We do not sell to patients.

Cephalotaxine Chemical Structure

Cephalotaxine Chemical Structure

CAS No. : 24316-19-6

Size Price Stock Quantity
Solution
10 mM * 1 mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
USD 55 In-stock
Estimated Time of Arrival: December 31
Solid
5 mg USD 50 In-stock
Estimated Time of Arrival: December 31
10 mg USD 70 In-stock
Estimated Time of Arrival: December 31
50 mg USD 180 In-stock
Estimated Time of Arrival: December 31
100 mg USD 280 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Description

Cephalotaxlen ((-)-Cephalotaxine) is an alkaloid that can be isolated from Cephalotaxus drupacea, with antileukemic and antiviral activities. Cephalotaxlen has anti-ZIKV (Zika virus) activity[1][2][3].

IC50 & Target

ZIKV[3]

In Vitro

Cephalotaxine inhibits Zika infection by impeding viral replication and stability[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

315.36

Formula

C₁₈H₂₁NO₄

CAS No.
SMILES

O[[email protected]]1[[email protected]](C(C=C(OCO2)C2=C3)=C3CCN4CCC5)([H])[[email protected]]45C=C1OC

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (317.10 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.1710 mL 15.8549 mL 31.7098 mL
5 mM 0.6342 mL 3.1710 mL 6.3420 mL
10 mM 0.3171 mL 1.5855 mL 3.1710 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (7.93 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (7.93 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (7.93 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Cephalotaxine(-)-Cephalotaxine ZINC19795976ZINC19795976ZINC 19795976ZINC-19795976Influenza VirusInhibitorinhibitorinhibit

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Product Name:
Cephalotaxine
Cat. No.:
HY-N0838
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