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Results for "

corylifolia

" in MedChemExpress (MCE) Product Catalog:

13

Inhibitors & Agonists

11

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N7504

    Bacterial Infection Metabolic Disease Cancer
    Isopsoralenoside is a benzofuran glycoside from Psoralea corylifolia. Isopsoralenoside can be quickly metabolized to Psoralen (HY-N0053) in digestive tract contents. Isopsoralenoside show estrogen-like activity, osteoblastic proliferation accelerating activity, antitumor effects and antibacterial activity .
    Isopsoralenoside
  • HY-N0720
    Neobavaisoflavone
    Maximum Cited Publications
    10 Publications Verification

    Apoptosis DNA/RNA Synthesis Cancer
    Neobavaisoflavone, a flavonoid, is isolated from the seeds of Psoralea corylifolia. Neobavaisoflavone exhibits anti-inflammatory, anti-cancer and anti-oxidation activities. Neobavaisoflavone inhibits DNA polymerase at moderate to high concentrations. Neobavaisoflavone also inhibits platelet aggregation .
    Neobavaisoflavone
  • HY-N7503

    Histamine Receptor Calcium Channel Calmodulin Infection Metabolic Disease Cancer
    Psoralenoside is a benzofuran glycoside from Psoralea corylifolia . Psoralenoside exhibits high binding affinities against histaminergic H1, calmodulin, and voltage-gated L-type calcium channels (E-value≥-6.5 Kcal/mol) . Psoralenoside shows estrogen-like activity, osteoblastic proliferation accelerating activity, antitumor effects and antibacterial activity .
    Psoralenoside
  • HY-N0231
    Bavachalcone
    1 Publications Verification

    Broussochalcone B

    Bacterial Antibiotic Infection Cancer
    Bavachalcone is a major bioactive compounds isolated from Psoralea corylifolia L.
    Bavachalcone
  • HY-N10820

    Bacterial Infection
    Psoracorylifol C is a natural product. Psoracorylifol C has important activity against Helicobacter pylori. Psoracorylifol C can be isolated from the seeds of Psoralea corylifolia .
    Psoracorylifol C
  • HY-121236

    Others Others
    Bavachromene is a chromenochalcone from the seeds of Psoralea corylifolia with estrogenic activities .
    Bavachromene
  • HY-N0235
    Bakuchiol
    1 Publications Verification

    (S)-(+)-Bakuchiol

    p38 MAPK Autophagy Cancer
    Bakuchiol is a phytoestrogen isolated from the seeds of Psoralea corylifolia L; has anti-tumor effects.
    Bakuchiol
  • HY-N0762
    Isobavachin
    2 Publications Verification

    Others Neurological Disease
    Isobavachin, an antioxidant isaolated from Psoralea corylifolia with a prenyl group at position 8 of ring A, promotes neuronal differentiation and the potential role of its protein prenylation .
    Isobavachin
  • HY-N0233
    Bavachin
    5 Publications Verification

    Corylifolin

    Estrogen Receptor/ERR Cancer
    Bavachin, a flavonoid first isolated from seeds of P. corylifolia, acts as a phytoestrogen that activates the estrogen receptors ERα and ERβ with EC50s of 320 and 680 nM, respectively.
    Bavachin
  • HY-N1910
    4'-O-Methylbavachalcone
    1 Publications Verification

    4'-O-Methylbavachalcone is a chalcone isolated from Psoralea corylifolia, inhibits severe acute respiratory syndrome coronavirus (SARS-CoV) papain-like protease (PLpro) activity, with an IC50 of 10.1 μM .
    4'-O-Methylbavachalcone
  • HY-N2208
    4-Hydroxylonchocarpin
    1 Publications Verification

    4-Hydroxylonchocarpin is a chalcone compound from an extract of Psoralea corylifolia. 4-Hydroxylonchocarpin increases phosphorylation of p38 MAPK, JNK and ERK. 4-Hydroxylonchocarpin has diverse pharmacological activities, including antibacterial, antifungal, anticancer, antireverse transcriptase, antitubercular, antimalarial, anti-inflammatory and antioxidant activities .
    4-Hydroxylonchocarpin
  • HY-13065
    Isobavachalcone
    5+ Cited Publications

    Corylifolinin; Isobacachalcone

    Akt Reactive Oxygen Species Apoptosis Autophagy Cancer
    Isobavachalcone (Corylifolinin) is derived from Psoralea corylifolia Linn. and is a potent inhibitor of Akt signaling pathway, which induces apoptosis in human cancer cells (Inhibits OVCAR-8 cell growth with an IC50 value of 7.92 μM). Isobavachalcone also induces Reactive Oxyen Species (ROS) generation in OVCAR-8 cells and has exhibit cancer anti-promotive and anti-proliferative activity .
    Isobavachalcone
  • HY-N7506

    Delta3,2-Hydroxylbakuchiol

    Monoamine Transporter Dopamine Transporter Neurological Disease
    Hydroxyisobakuchiol (Delta3,2-Hydroxylbakuchiol), an analog of Bakuchiol (HY-N0235) isolated from Psoralea corylifolia (L.), is a potent monoamine transporter inhibitor. 13-Hydroxyisobakuchiol is more selective for the dopamine transporter (DAT) (IC50=0.58 μM) and norepinephrine transporter (NET) (IC50=0.69 μM) than for the serotonin transporter (SERT) (IC50=312.02 μM). 13-Hydroxyisobakuchiol has the potential for the research of disorders such as Parkinson's disease and depression .
    13-Hydroxyisobakuchiol

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