1. Membrane Transporter/Ion Channel
    Neuronal Signaling
  2. Monoamine Transporter
    Dopamine Transporter
  3. 13-Hydroxyisobakuchiol

13-Hydroxyisobakuchiol (Synonyms: Delta3,2-Hydroxylbakuchiol)

Cat. No.: HY-N7506
Handling Instructions

Hydroxyisobakuchiol (Delta3,2-Hydroxylbakuchiol), an analog of Bakuchiol (HY-N0235) isolated from Psoralea corylifolia (L.), is a potent monoamine transporter inhibitor. 13-Hydroxyisobakuchiol is more selective for the dopamine transporter (DAT) (IC50=0.58 μM) and norepinephrine transporter (NET) (IC50=0.69 μM) than for the serotonin transporter (SERT) (IC50=312.02 μM). 13-Hydroxyisobakuchiol has the potential for the research of disorders such as Parkinson's disease, depression, and cocaine addiction.

For research use only. We do not sell to patients.

13-Hydroxyisobakuchiol Chemical Structure

13-Hydroxyisobakuchiol Chemical Structure

CAS No. : 178765-49-6

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Description

Hydroxyisobakuchiol (Delta3,2-Hydroxylbakuchiol), an analog of Bakuchiol (HY-N0235) isolated from Psoralea corylifolia (L.), is a potent monoamine transporter inhibitor. 13-Hydroxyisobakuchiol is more selective for the dopamine transporter (DAT) (IC50=0.58 μM) and norepinephrine transporter (NET) (IC50=0.69 μM) than for the serotonin transporter (SERT) (IC50=312.02 μM). 13-Hydroxyisobakuchiol has the potential for the research of disorders such as Parkinson's disease, depression, and cocaine addiction[1].

IC50 & Target

IC50: 0.58 μM (dopamine transporter)
IC50: 0.69 μM (norepinephrine transporter)[1]

Molecular Weight

272.38

Formula

C₁₈H₂₄O₂

CAS No.

178765-49-6

SMILES

OC1=CC=C(/C=C/[[email protected]](C)(C=C)C/C=C/C(C)(O)C)C=C1

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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

13-HydroxyisobakuchiolDelta3,2-HydroxylbakuchiolMonoamine TransporterDopamine TransporterDATSLC6A3monoamine transporterdopamine transporternorepinephrine transporterParkinson's diseasedepressioncocaine addictionInhibitorinhibitorinhibit

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