Search Result

Results for "

detoxification

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Endogenous Metabolite (7) Glutathione S-transferase (2) Reactive Oxygen Species (2)
By Research Areas:	Cancer (4) Metabolic Disease (4)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-D0844

Glutathione oxidized 3 Publications Verification L-Glutathione oxidized; GSSG; Oxiglutatione	Endogenous Metabolite Reactive Oxygen Species	Metabolic Disease
Glutathione oxidized (L-Glutathione oxidized) is produced by the oxidation of glutathione. Detoxification of reactive oxygen species is accompanied by production of glutathione oxidized. Glutathione oxidized can be used for the research of sickle cells and erythrocytes .

HY-115772

4′-Bromoflavone

Others Cancer

4′-Bromoflavone, a cancer chemopreventive agent, is a potent phase II detoxification enzymes inducer .

4′-Bromoflavone	Others	Cancer
4′-Bromoflavone, a cancer chemopreventive agent, is a potent phase II detoxification enzymes inducer .

HY-W020788

Benoxacor CGA 154281	Glutathione S-transferase	Others
Benoxacor (CGA 154281) is a herbicide safener that can protect crops from the toxicity of herbicides. Benoxacor can enhance the activity of glutathione S-transferase (GST) in corn, effectively inducing detoxification of herbicides in corn .

HY-N11562

Aristololactam II	Others	Others
Aristololactam II, a metabolite of Aristolochic acid II (AAII), is an excretion product found in the urine, which is considered to be detoxification metabolite of AAII .

HY-P2740

Alcohol dehydrogenase EC 1.1.1.1	Endogenous Metabolite	Metabolic Disease
Alcohol dehydrogenase is a dimeric protein in the cytosol of cells. Alcohol dehydrogenase, the key enzyme for alcohol consumption in the body, is the highest expressed in the liver and participates in the detoxification mechanism of environmental alcohol .

HY-N10344

Glucoarabin	Others	Cancer
Glucoarabin is a bioactive glucosinolate. In Hepa1c1c7 cells, hydrolyzed Glucoarabin (hGSL 9) upregulates the phase II detoxification enzyme quinone reductase (NQO1), with no effect on cytochrome P450 (CYP) 1A1 activity .

HY-132178

Cytochrome P450	Endogenous Metabolite	Metabolic Disease
Cytochrome P450 is a family of monooxygenase enzymes that catalyzes the conversion of fatty acids to terminal alkenes using hydrogen peroxide as a cosubstrate. Cytochrome P450 as membrane-bound hemoproteins, plays important roles in the detoxification of drugs, cellular metabolism, and homeostasis .

HY-113325

NADP 4 Publications Verification	Endogenous Metabolite	Others
NADP, a nicotinamide adenine dinucleotide, is a redox cofactor. NADP is a key cofactor for electron transfer in the metabolism, being alternately oxidized (NADP ⁺) and reduced (NADPH). NADPH is the universal electron donor in cellular reductive biosyntheses and detoxification processes, and also plays a key role in oxidative defense system .

HY-F0002

NADP sodium salt 4 Publications Verification Sodium NADP	Endogenous Metabolite	Others
NADP sodium salt is the sodium salt form of NADP (HY-113325). NADP, a nicotinamide adenine dinucleotide, is a redox cofactor. NADP is a key cofactor for electron transfer in the metabolism, being alternately oxidized (NADP ⁺) and reduced (NADPH). NADPH is the universal electron donor in cellular reductive biosyntheses and detoxification processes, and also plays a key role in oxidative defense system .

HY-D0844S

Glutathione oxidized-13C4,15N2 1 Publications Verification L-Glutathione oxidized-¹³C₄,¹⁵N₂; GSSG-¹³C₄,¹⁵N₂; Oxiglutatione-¹³C₄,¹⁵N₂	Endogenous Metabolite Reactive Oxygen Species	Metabolic Disease
Glutathione oxidized- ¹³C₄, ¹⁵N₂ is the ¹³C and ¹⁵N labeled Glutathione oxidized (HY-D0844). Glutathione oxidized is produced by the oxidation of glutathione. Detoxification of reactive oxygen species is accompanied by production of glutathione oxidized. Glutathione oxidized can be used for the research of sickle cells and erythrocytes[1][2].

HY-F0002A

NADP disodium salt 4 Publications Verification Disodium NADP	Endogenous Metabolite	Others
NADP disodium salt is the disodium salt form of NADP (HY-113325). NADP, a nicotinamide adenine dinucleotide, is a redox cofactor. NADP is a key cofactor for electron transfer in the metabolism, being alternately oxidized (NADP ⁺) and reduced (NADPH). NADPH is the universal electron donor in cellular reductive biosyntheses and detoxification processes, and also plays a key role in oxidative defense system .

HY-N0548

α-Angelica lactone 2 Publications Verification	Glutathione S-transferase	Cancer
α-Angelica lactone is a naturally occurring anticarcinogen and an vinylogous nucleophile. α-Angelica lactone can give the chiral δ-amino γ,γ-disubstituted butenolide carbonyl derivatives and exhibitselectrophilic trapping at the γ-carbon. α-Angelica lactone exerts strong chemoprotective effects by selective enhancement of glutathione-S-thansferase (GST) and *UDP-glucononosyltransferase (UGT) detoxification* enzymes** .

HY-N6802

Tigloylgomisin H	Others	Cancer
Tigloylgomisin H is a lignan isolated from the fruits of S. chinensis, can induce quinone reductase (QR) activity in Hepa1c1c7 mouse hepatocarcinoma cells. Tigloylgomisin H functions as a monofunctional inducer that specifically upregulates phase II detoxification enzyme NQO1 through the NF-E2-related factor 2 (Nrf2)-ARE pathway, thus represents a potential liver cancer prevention agent .

Alcohol dehydrogenase EC 1.1.1.1	Biochemical Assay Reagents
Alcohol dehydrogenase is a dimeric protein in the cytosol of cells. Alcohol dehydrogenase, the key enzyme for alcohol consumption in the body, is the highest expressed in the liver and participates in the detoxification mechanism of environmental alcohol .

Glutathione oxidized 3 Publications Verification L-Glutathione oxidized; GSSG; Oxiglutatione	Endogenous Metabolite Reactive Oxygen Species	Metabolic Disease
Glutathione oxidized (L-Glutathione oxidized) is produced by the oxidation of glutathione. Detoxification of reactive oxygen species is accompanied by production of glutathione oxidized. Glutathione oxidized can be used for the research of sickle cells and erythrocytes .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-D0844

Glutathione oxidized 3 Publications Verification L-Glutathione oxidized; GSSG; Oxiglutatione	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite Reactive Oxygen Species
Glutathione oxidized (L-Glutathione oxidized) is produced by the oxidation of glutathione. Detoxification of reactive oxygen species is accompanied by production of glutathione oxidized. Glutathione oxidized can be used for the research of sickle cells and erythrocytes .

HY-113325

NADP 4 Publications Verification	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
NADP, a nicotinamide adenine dinucleotide, is a redox cofactor. NADP is a key cofactor for electron transfer in the metabolism, being alternately oxidized (NADP ⁺) and reduced (NADPH). NADPH is the universal electron donor in cellular reductive biosyntheses and detoxification processes, and also plays a key role in oxidative defense system .

HY-N11562

Aristololactam II	Structural Classification Alkaloids Stephania cepharantha Hayata Pyrrole Alkaloids Source classification Plants Menispermaceae	Others
Aristololactam II, a metabolite of Aristolochic acid II (AAII), is an excretion product found in the urine, which is considered to be detoxification metabolite of AAII .

HY-N10344

Glucoarabin	Structural Classification Natural Products Classification of Application Fields Source classification Camelina sativa (L.) Crantz Glucosinolates Plants Brassicaceae Disease Research Fields Cancer	Others
Glucoarabin is a bioactive glucosinolate. In Hepa1c1c7 cells, hydrolyzed Glucoarabin (hGSL 9) upregulates the phase II detoxification enzyme quinone reductase (NQO1), with no effect on cytochrome P450 (CYP) 1A1 activity .

HY-132178

Cytochrome P450	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Cytochrome P450 is a family of monooxygenase enzymes that catalyzes the conversion of fatty acids to terminal alkenes using hydrogen peroxide as a cosubstrate. Cytochrome P450 as membrane-bound hemoproteins, plays important roles in the detoxification of drugs, cellular metabolism, and homeostasis .

HY-F0002A

NADP disodium salt 4 Publications Verification Disodium NADP	Structural Classification other families Microorganisms Classification of Application Fields Animals Ketones, Aldehydes, Acids Source classification Other Diseases Plants Disease Research Fields	Endogenous Metabolite
NADP disodium salt is the disodium salt form of NADP (HY-113325). NADP, a nicotinamide adenine dinucleotide, is a redox cofactor. NADP is a key cofactor for electron transfer in the metabolism, being alternately oxidized (NADP ⁺) and reduced (NADPH). NADPH is the universal electron donor in cellular reductive biosyntheses and detoxification processes, and also plays a key role in oxidative defense system .

HY-N0548

α-Angelica lactone 2 Publications Verification	Natural Products Classification of Application Fields Source classification Dicerothamnus rhinocerotis Plants Umbelliferae Disease Research Fields Cancer	Glutathione S-transferase
α-Angelica lactone is a naturally occurring anticarcinogen and an vinylogous nucleophile. α-Angelica lactone can give the chiral δ-amino γ,γ-disubstituted butenolide carbonyl derivatives and exhibitselectrophilic trapping at the γ-carbon. α-Angelica lactone exerts strong chemoprotective effects by selective enhancement of glutathione-S-thansferase (GST) and *UDP-glucononosyltransferase (UGT) detoxification* enzymes** .

HY-N6802

Tigloylgomisin H	Structural Classification Classification of Application Fields Source classification Lignans Phenylpropanoids Plants Schisandraceae Disease Research Fields Schisandra chinensis (Turcz.) Baill. Cancer	Others
Tigloylgomisin H is a lignan isolated from the fruits of S. chinensis, can induce quinone reductase (QR) activity in Hepa1c1c7 mouse hepatocarcinoma cells. Tigloylgomisin H functions as a monofunctional inducer that specifically upregulates phase II detoxification enzyme NQO1 through the NF-E2-related factor 2 (Nrf2)-ARE pathway, thus represents a potential liver cancer prevention agent .

Cat. No.	Product Name	Chemical Structure

HY-D0844S

Glutathione oxidized-13C4,15N2 1 Publications Verification
Glutathione oxidized- ¹³C₄, ¹⁵N₂ is the ¹³C and ¹⁵N labeled Glutathione oxidized (HY-D0844). Glutathione oxidized is produced by the oxidation of glutathione. Detoxification of reactive oxygen species is accompanied by production of glutathione oxidized. Glutathione oxidized can be used for the research of sickle cells and erythrocytes[1][2].

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

Name
Email *

	Sorry, but the email address you supplied was invalid.

detoxification

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

NaturalProducts

Isotope-Labeled Compounds

Natural
Products