Glutathione oxidized-13C4,15N2
Based on 2 publication(s) in Google Scholar
Glutathione oxidized-13C4,15N2 is the 13C and 15N labeled Glutathione oxidized (HY-D0844). Glutathione oxidized is produced by the oxidation of glutathione. Detoxification of reactive oxygen species is accompanied by production of glutathione oxidized. Glutathione oxidized can be used for the research of sickle cells and erythrocytes.
For research use only. We do not sell to patients.
- Purity: 99.9%
- CAS No.: 1416898-83-3
- Formula: C1613C4H32N415N2O12S2
- Molecular Weight:618.59
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Glutathione oxidized-13C4,15N2
MoreAll Endogenous Metabolite Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1416898-83-3
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Unlabeled Cas 27025-41-8
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Appearance Solid
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Molecular Weight 618.59
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Formula C1613C4H32N415N2O12S2
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Color White to off-white
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SMILES
OC([C@@H](N)CCC(N[C@@H](CSSC[C@@H](C([15NH][13CH2][13C](O)=O)=O)NC(CC[C@H](N)C(O)=O)=O)C([15NH][13CH2][13C](O)=O)=O)=O)=O
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Synonyms
L-Glutathione oxidized-13C4,15N2; GSSG-13C4,15N2; Oxiglutatione-13C4,15N2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (2)
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Journal Impact Factor
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Most Recent
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Cell Rep Med
2023 Jun 20;4(6):101061. PMID: 37267943 -
J Agric Food Chem
Quantification of Stress- and Resistance-Related Metabolites in Barley Leaves (Hordeum vulgare L.) Infected with Bipolaris sorokiniana via UHPLC-MS/MSMRM. [Abstract]2026 Jul 1;74(25):20051-20061. PMID: 42299507
Solvent & Solubility
H2O : 250 mg/mL (404.14 mM; Need ultrasonic)
H2O : 250 mg/mL (404.14 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223. [Content Brief]
[2]. Nur E, et al. Increased efflux of oxidized glutathione (GSSG) causes glutathione depletion and potentially diminishes antioxidant defense in sickle erythrocytes. Biochim Biophys Acta. 2011 Nov;1812(11):1412-7. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| H2O / H2O | 1 mM | 1.6166 mL | 8.0829 mL | 16.1658 mL | 40.4145 mL |
| 5 mM | 0.3233 mL | 1.6166 mL | 3.2332 mL | 8.0829 mL | |
| 10 mM | 0.1617 mL | 0.8083 mL | 1.6166 mL | 4.0414 mL | |
| 15 mM | 0.1078 mL | 0.5389 mL | 1.0777 mL | 2.6943 mL | |
| 20 mM | 0.0808 mL | 0.4041 mL | 0.8083 mL | 2.0207 mL | |
| 25 mM | 0.0647 mL | 0.3233 mL | 0.6466 mL | 1.6166 mL | |
| 30 mM | 0.0539 mL | 0.2694 mL | 0.5389 mL | 1.3471 mL | |
| 40 mM | 0.0404 mL | 0.2021 mL | 0.4041 mL | 1.0104 mL | |
| 50 mM | 0.0323 mL | 0.1617 mL | 0.3233 mL | 0.8083 mL | |
| 60 mM | 0.0269 mL | 0.1347 mL | 0.2694 mL | 0.6736 mL | |
| 80 mM | 0.0202 mL | 0.1010 mL | 0.2021 mL | 0.5052 mL | |
| 100 mM | 0.0162 mL | 0.0808 mL | 0.1617 mL | 0.4041 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Glutathione oxidized-13C4,15N2 Related Classifications
HY-D0844S Related Classifications
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