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homoserine

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48

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8

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11

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1

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-119543

    Amino Acid Derivatives Others
    O-Succinyl-L-homoserine is a homoserine derivative. O-Succinyl-L-homoserine is an intermediate in the biosynthesis of methionine in Escherichia coli and Salmonella typhimurium .
    O-Succinyl-L-<em>homoserine</em>
  • HY-113801

    (Rac)-3-oxo-C8-HSL

    Others Metabolic Disease
    N-(3-Oxooctanoyl)-DL-homoserine lacton is a member of N-Acyl homoserine lactone (AHL) from gram-negative bacteria, with stereochemistry-dependent growth regulatory activity for roots .
    N-(3-Oxooctanoyl)-DL-<em>homoserine</em> lactone
  • HY-133683

    3-Oxo-C14-AHL

    Others Metabolic Disease
    N-(3-Oxotetradecanoyl)-DL-homoserine lactone, a member of N-Acyl homoserine lactone (AHL) from gram-negative bacteria, is a quorum sensing (QS) signaling molecule .
    N-(3-Oxotetradecanoyl)-DL-<em>homoserine</em> lactone
  • HY-123087

    N-(3-oxodecanoyl)-homoserine lactone

    Bacterial Infection
    N-(3-Hydroxytetradecanoyl)-DL-homoserine lactone (N-(3-oxodecanoyl)-homoserine lactone) is a member of N-Acyl homoserine lactone (AHL) from V. alginolyticus strains. N-(3-Hydroxytetradecanoyl)-DL-homoserine lactone is used for biofilm formation and has antibacterial activity .
    N-(3-Hydroxytetradecanoyl)-DL-<em>homoserine</em> lactone
  • HY-W036160

    Amino Acid Derivatives Others
    N-Fmoc-O-ethyl-L-homoserine is an homoserine derivative, can be used in cyclic peptide compounds synthesis, as a reducing reagent .
    N-Fmoc-O-ethyl-L-<em>homoserine</em>
  • HY-W025723A

    N-(Benzyloxycarbonyl)-D-homoserine

    Others Cancer
    N-Carbobenzoxy-D-homoserine (N-(Benzyloxycarbonyl)-D-homoserine) is D-homoserine with N-Carbobenzoxy protecting group, which can be used to synthesize Antibody-Drug Conjugates (ADCs).
    N-Carbobenzoxy-D-<em>homoserine</em>
  • HY-W025723

    N-(Benzyloxycarbonyl)-L-homoserine

    Others Cancer
    N-Carbobenzoxy-L-homoserine (N-(Benzyloxycarbonyl)-L-homoserine) is L-homoserine with N-Carbobenzoxy protecting group, which can be used as a linker (ADC Linker) for the synthesis of Antibody-Drug Conjugates (ADCs).
    N-Carbobenzoxy-L-<em>homoserine</em>
  • HY-W008113

    Amino Acid Derivatives Others
    Boc-L-Homoserine is a serine derivative .
    Boc-L-<em>Homoserine</em>
  • HY-W017788

    Amino Acid Derivatives Others
    Boc-D-Homoserine is a serine derivative .
    Boc-D-<em>Homoserine</em>
  • HY-115393A

    Bacterial Infection
    N-Heptanoyl-L-homoserine lactone is a member of N-acyl-homoserine lactone family. N-acyl-homoserine lactones (AHL) can regulate gene expression in gram-negative bacteria, such as Echerichia and Salmonella, and are involved in quorum sensing, cell to cell communication among bacteria.
    N-Heptanoyl-L-<em>homoserine</em> lactone
  • HY-W002292

    Endogenous Metabolite Others
    L-Homoserine is a non - protein amino acid, which is an important biosynthetic intermediate of threonine, methionine and lysine.
    L-<em>Homoserine</em>
  • HY-129405

    Bacterial Infection
    N-(Ketocaproyl)-DL-homoserine lactone is a natural, very active ligand of LuxR. N-(Ketocaproyl)-DL-homoserine lactone is a quorum sensing (QS) autoinducer .
    N-(Ketocaproyl)-DL-<em>homoserine</em> lactone
  • HY-114816

    C4-HSL; N-Butyryl-L-homoserine lactone

    ADC Linker Bacterial Infection Inflammation/Immunology
    N-Butanoyl-L-homoserine lactone (C4-HSL) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Butanoyl-L-homoserine lactone has antibacterial activity and is used in antibacterial biofilm . N-Butanoyl-L-homoserine lactone aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa .
    N-Butanoyl-L-<em>homoserine</em> lactone
  • HY-114816S

    Isotope-Labeled Compounds ADC Linker Bacterial Infection Inflammation/Immunology
    N-butyryl-L-Homoserine lactone-d5 is the deuterium labeled N-Butanoyl-L-homoserine lactone. N-Butanoyl-L-homoserine lactone (C4-HSL) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Butanoyl-L-homoserine lactone has antibacterial activity and is used in antibacterial biofilm[1]. N-Butanoyl-L-homoserine lactone aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa[2][3].
    N-butyryl-L-<em>Homoserine</em> lactone-d5
  • HY-113764

    (Rac)-C4-HSL

    Bacterial Infection Inflammation/Immunology
    N-Butanoyl-DL-homoserine lactone ((Rac)-C4-HSL) is a racemic mixture of N-Butanoyl-D-homoserine lactone and N-Butanoyl-L-homoserine lactone. N-Butanoyl-L-homoserine lactone is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Butanoyl-L-homoserine lactone has antibacterial activity and is used in antibacterial biofilm. N-Butanoyl-L-homoserine lactone aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa .
    N-Butanoyl-DL-<em>homoserine</em> lactone
  • HY-W008806

    OHHL; N-(3-Oxohexanoyl)homoserine lactone

    Bacterial Infection Inflammation/Immunology
    N-(β-ketocaproyl)-L-Homoserine lactone is a component of quorum regulatory sensing .
    N-(3-Oxohexanoyl)-L-<em>homoserine</em> lactone
  • HY-133684

    Bacterial Infection
    N-Tetradecanoyl-L-homoserine lactone is a short-chained N-acyl homoserine lactone (AHL). Diatoms are frequently found in association with Proteobacteria, many members of which employ cell-to-cell communication via AHLs in aquatic habitats .
    N-Tetradecanoyl-L-<em>homoserine</em> lactone
  • HY-133685

    Bacterial Infection
    N-Hexanoyl-L-homoserine lactone is a short-chained N-acyl homoserine lactone (AHL). Diatoms are frequently found in association with Proteobacteria, many members of which employ cell-to-cell communication via AHLs in aquatic habitats .
    N-Hexanoyl-L-<em>homoserine</em> lactone
  • HY-W044573

    Amino Acid Derivatives Others
    N-Dodecanoyl-DL-homoserine lactone is a serine derivative .
    N-Dodecanoyl-DL-<em>homoserine</em> lactone
  • HY-W045072

    Amino Acid Derivatives Others
    N-Decanoyl-DL-homoserine lactone is a serine derivative .
    N-Decanoyl-DL-<em>homoserine</em> lactone
  • HY-W142093

    Amino Acid Derivatives Others
    N-Tetradecanoyl-DL-homoserine lactone is a serine derivative .
    N-Tetradecanoyl-DL-<em>homoserine</em> lactone
  • HY-115393

    Amino Acid Derivatives Others
    N-Heptanoyl-DL-homoserine lactone is a serine derivative .
    N-Heptanoyl-DL-<em>homoserine</em> lactone
  • HY-124237A

    Bacterial Infection
    N-octanoyl-L-Homoserine lactone is a small diffusible signaling molecule involved in quorum sensing, thereby controlling gene expression and affecting cellular metabolism. N-octanoyl-L-Homoserine lactone can be used for the infection prevention and regulation of virulence in cystic fibro.
    N-Octanoyl-L-<em>homoserine</em> lactone
  • HY-W015800

    Biochemical Assay Reagents Others
    L-Homoserine lactone hydrochloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    L-<em>Homoserine</em> lactone hydrochloride
  • HY-W045071

    Bacterial Infection
    N-Hexanoyl-DL-homoserine lactone is a bacterial quorum sensing molecule produced in the rhizosphere. N-Hexanoyl-DL-homoserine lactone, a bacterial quorum sensing signal, induces transcriptional changes in Arabidopsis and may contribute to tuning plant growth to the microbial composition of the rhizosphere .
    N-Hexanoyl-DL-<em>homoserine</em> lactone
  • HY-136409

    C10-HSL

    Bacterial Reactive Oxygen Species Infection
    N-decanoyl-L-homoserine lactone (C10-HSL) is a N-acyl-homoserine lactone (AHL) N-decanoyl-L-homoserine lactone can inhibit primary root growth in Arabidopsis. N-decanoyl-L-homoserine lactone triggers a transient and immediate increase in the concentrations of cytosolic free Ca 2+ and reactive oxygen species (ROS), increases the activity of mitogen-activated protein kinase 6 (MPK6), and induces nitric oxide (NO) production in Arabidopsis roots .
    N-Decanoyl-L-<em>homoserine</em> lactone
  • HY-120242

    Antibiotic Infection
    N-(3-Oxobutanoyl)-L-homoserine lactone (3-oxo-C4-HSL) is a carbapenem antibiotic biosynthesis autoregulator in Erwinia carotovora ATCC 39048. N-(3-Oxobutanoyl)-L-homoserine lactone induces expression of rhiI in R. leguminosarum .
    N-(3-Oxobutanoyl)-L-<em>homoserine</em> lactone
  • HY-W127610

    Biochemical Assay Reagents Others
    N-hexadecanoyl-L-Homoserine lactone is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    N-hexadecanoyl-L-<em>Homoserine</em> lactone
  • HY-137407

    Bacterial Infection
    N-Phenylacetyl-L-homoserine lactone is a small diffusible signaling molecule that strongly antagonizes or super-activates the quorum sensing of Vibrio fischeri .
    N-Phenylacetyl-L-<em>homoserine</em> lactone
  • HY-118697

    C12-HSL

    Others Infection
    N-dodecanoyl-L-Homoserine lactone (C12-HSL) is a quorum sensing (QS) signaling molecule. N-dodecanoyl-L-Homoserine lactone (C12-HSL) aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa .
    N-dodecanoyl-L-<em>Homoserine</em> lactone
  • HY-108700

    SOD Infection
    N-3-Oxo-octanoyl-L-homoserine lactone, a quorum-sensing signal, is an Agrobacterium autoinducer .
    N-3-Oxo-octanoyl-L-<em>homoserine</em> lactone
  • HY-141641

    HSL

    Bacterial
    N-(3-Oxopentanoyl)-L-homoserine lactone is an autoinducer, a kind of chemical signal molecule which passively diffuses across the bacterial envelope and accumulates intracellularly at high bacterial densities. It may bind to a protein related to the LuxR protein of V. fischeri and causes cell density-dependent gene expression. N-(3-Oxopentanoyl)-L-homoserine can be used for research of quorum sensing .
    N-(3-Oxopentanoyl)-L-<em>homoserine</em> lactone
  • HY-N12107

    Others Others
    N-[(Z)-Hexadec-9-enoyl]homoserine lactone (Compound 2) is a compound that can be isolated from Roseovarius tolerans .
    N-[(Z)-Hexadec-9-enoyl]<em>homoserine</em> lactone
  • HY-115399A

    3-Oxo-C16-AHL

    Bacterial Metabolic Disease
    N-3-Oxo-hexadecanoyl-L-Homoserine lactone is a signaling molecule to coordinate group behaviors at high densities in many bacteria. N-3-Oxo-hexadecanoyl-L-Homoserine lactone adsorbs to and promotes the remodeling of lipid membranes in ways that could underpin cell-cell or host-cell interactions .
    N-3-Oxo-hexadecanoyl-L-<em>Homoserine</em> lactone
  • HY-145462

    Bacterial Infection
    N-cis-octadec-9Z-enoyl-L-Homoserine lactone is a potent inhibitor of AhyI. AhyI (expressing acylhomoserine lactone) is responsible for the biosynthesis of autoinducer-1 (AI-1), commonly referred to as a quorum sensing (QS) signaling molecule, which plays an essential role in bacterial communication. N-cis-octadec-9Z-enoyl-L-Homoserine lactone is a competitive inhibitor of AI-1 biosynthesis .
    N-cis-Octadec-9Z-enoyl-L-<em>homoserine</em> lactone
  • HY-114544A

    OdDHL

    Bacterial Others
    N-3-oxo-dodecanoyl-L-Homoserine lactone (3-oxo-C12-HSL) is a bacterial quorum-sensing signaling molecule produced by P. aeruginosa and strains of the B. cepacia complex .Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density.N-3-oxo-dodecanoyl-L-Homoserine lactone induces the production of IL-8 in 16HBE human bronchial epithelial cells .
    N-3-oxo-dodecanoyl-L-<em>homoserine</em> lactone
  • HY-W048668

    Amino Acid Derivatives Others
    N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-O-trityl-L-homoserine is a serine derivative .
    N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-O-trityl-L-<em>homoserine</em>
  • HY-134560

    3-Oxo-C10-HSL

    Others Inflammation/Immunology
    N-(3-Oxodecanoyl)-L-homoserine lactone (3-Oxo-C10-HSL) is a bacterial quorum sensing signal autoinducer molecule .
    N-(3-Oxodecanoyl)-L-<em>homoserine</em> lactone
  • HY-W127486

    Biochemical Assay Reagents Others
    N-3-oxo-hexadec-11Z-enoyl-L-Homoserine lactone is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    N-3-oxo-Hexadec-11Z-enoyl-L-<em>homoserine</em> lactone
  • HY-116536

    oxo-C14-HSL

    Bacterial Infection
    N-3-Oxo-tetradecanoyl-L-homoserine lactone (oxo-C14-HSL) is a rhizobacterial inducer and can improve basic defense against nematodes .
    N-3-Oxo-tetradecanoyl-L-<em>homoserine</em> lactone
  • HY-W127487

    Biochemical Assay Reagents Others
    Quorum sensing is a regulatory system used by bacteria to control gene expression in response to increased cell density. This regulatory process manifests itself in a variety of phenotypes, including biofilm formation and virulence factor production. Coordinated gene expression is achieved through the production, release and detection of small diffusible signaling molecules called autoinducers. N-acylated homoserine lactones (AHLs) comprise a class of such autoinducers, each of which generally consists of a fatty acid coupled to a homoserine lactone (HSL). Modulation of bacterial quorum-sensing signaling systems to suppress pathogenesis represents a new approach to antimicrobial research for infectious diseases. AHLs differ in acyl length (C4-C18), C3 substitution (hydrogen, hydroxyl, or oxo group), and the presence or absence of one or more carbon-carbon double bonds in the fatty acid chain. These differences confer signaling specificity through the affinity of the LuxR family of transcriptional regulators. C18-HSL, one of four lipophilic long acyl side chain AHLs produced by the LuxI AHL synthase homolog SinI, is involved in quorum-sensing signaling in strains of Rhizobium meliloti (a nitrogen-fixing bacterial symbiont of the legume M. sativa) . C18-HSL and other hydrophobic AHLs tend to localize in the relatively lipophilic environment of bacterial cells and cannot diffuse freely across the cell membrane. Long-chain N-acyl homoserine lactones can be exported from cells by efflux pumps, or can be transported between communicating cells by extracellular outer membrane vesicles.
    N-Octadecanoyl-L-<em>homoserine</em> lactone
  • HY-114773

    Biochemical Assay Reagents Others
    Quorum sensing is a regulatory system used by bacteria to control gene expression in response to increased cell density. This regulatory process manifests itself in a variety of phenotypes, including biofilm formation and virulence factor production. Coordinated gene expression is achieved through the production, release and detection of small diffusible signaling molecules called autoinducers. N-acylated homoserine lactones (AHLs) comprise a class of such autoinducers, each of which generally consists of a fatty acid coupled to a homoserine lactone (HSL). Modulation of bacterial quorum-sensing signaling systems to suppress pathogenesis represents a new approach to antimicrobial research for infectious diseases. AHLs differ in acyl length (C4-C18), C3 substitution (hydrogen, hydroxyl, or oxo group), and the presence or absence of one or more carbon-carbon double bonds in the fatty acid chain. These differences confer signaling specificity through the affinity of the LuxR family of transcriptional regulators. C11-HSL has a rare odd-numbered acyl carbon chain and may be a minor quorum-sensing signaling molecule in Pseudomonas aeruginosa strains.
    N-Undecanoyl-L-<em>homoserine</em> lactone
  • HY-W127393

    Biochemical Assay Reagents Others
    Quorum sensing is a regulatory system used by bacteria to control gene expression in response to increased cell density. This regulatory process manifests itself in a variety of phenotypes, including biofilm formation and virulence factor production. Coordinated gene expression is achieved through the production, release and detection of small diffusible signaling molecules called autoinducers. N-acylated homoserine lactones (AHLs) comprise a class of such autoinducers, each of which generally consists of a fatty acid coupled to a homoserine lactone (HSL). Modulation of bacterial quorum-sensing signaling systems to suppress pathogenesis represents a new approach to antimicrobial research for infectious diseases. AHLs differ in acyl length (C4-C18), C3 substitution (hydrogen, hydroxyl, or oxo group), and the presence or absence of one or more carbon-carbon double bonds in the fatty acid chain. These differences confer signaling specificity through the affinity of the LuxR family of transcriptional regulators. C9-HSL is a rare odd-numbered acyl carbon chain produced by wild-type Erwinia carotovora strain SCC 3193 grown in nutrient-rich Luria-Bertani broth (LB) medium.
    N-Nonanoyl-L-<em>homoserine</em> lactone
  • HY-124286

    C14-9Z-HSL

    Bacterial Inflammation/Immunology
    N-cis-Tetradec-9Z-enoyl-L-homoserine lactone (C14-9Z-HSL) is an autoinducer in C. rodentium, that serves as signal molecule, coordinates the gene expression and behaviors through diffusion into cells of different bacterial species .
    N-cis-Tetradec-9Z-enoyl-L-<em>homoserine</em> lactone
  • HY-W012870

    Biochemical Assay Reagents Others
    H-DL-HoSer-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    DL-<em>Homoserine</em>
  • HY-116762

    Biochemical Assay Reagents Others
    Quorum sensing is a regulatory system used by bacteria to control gene expression in response to increased cell density. The control of bacterial infection by quenching the quorum sensing system of bacteria is a promising research area. The expression of specific target genes, such as transcriptional regulators belonging to the LuxIR protein family, is coordinated by the synthesis of diffusible acyl homoserine lactone (AHL) molecules. N-butyryl-L-Homocysteine thio-lactone is an analog of N-butyryl-L-homoserine lactone, a small, diffusible signaling molecule involved in quorum sensing, thereby controlling gene expression and cellular metabolism . N-butyryl-L-homocysteine thiolactone induces violacein expression in Viola viola mutants that normally fail to produce AHL.
    N-butyryl-L-Homocysteine thiolactone
  • HY-N10192

    Endogenous Metabolite Bacterial Infection
    Aculene D, a fungal metabolite, shows quorum sensing (QS) inhibitory activity against Chromobacterium violaceum CV026, and could significantly reduce violacein production in N-hexanoyl-l-homoserine lactone (C6-HSL) induced C. violaceum CV026 cultures at sub-inhibitory concentrations .
    Aculene D
  • HY-145492

    N-(3-Oxo-7Z-tetradecenoyl)-L-homoserine lactone

    Others Inflammation/Immunology
    Δ7(Z)-C14-HSL (Compound 12) is an immunosuppressive agent that can inhibit the proliferation of mouse splenic cells with an IC50 of 17 μM. Δ7(Z)-C14-HSL can be used for further studying its potential as a molecular mechanism in TNF-R-driven immune diseases, especially autoimmune diseases such as psoriasis, rheumatoid arthritis, and type 1 diabetes .
    Δ7(Z)-C14-HSL

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