N-(Ketocaproyl)-DL-homoserine lactone
Based on 1 Customer Validation
N-(Ketocaproyl)-DL-homoserine lactone is a natural, very active ligand of LuxR. N-(Ketocaproyl)-DL-homoserine lactone is a quorum sensing (QS) autoinducer.
For research use only. We do not sell to patients.
- Purity : 99.63%
- CAS No.: 76924-95-3
- Formula: C10H15NO4
- Molecular Weight:213.23
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
N-(Ketocaproyl)-DL-homoserine lactone is a natural ligand of Vibrio fischeri as L and D isomers[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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CAS No. 76924-95-3
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Appearance Solid
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Molecular Weight 213.23
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Formula C10H15NO4
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Color White to off-white
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SMILES
O=C1OCCC1NC(CC(CCC)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
H2O : 250 mg/mL (1172.44 mM; Need ultrasonic)
DMSO : 100 mg/mL (468.98 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo:
For the following dissolution methods, please prepare the working solution directly:
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: PBS
Solubility: 50 mg/mL (234.49 mM); Clear solution; Need ultrasonic
Purity & Documentation
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Data Sheet (270 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / H2O | 1 mM | 4.6898 mL | 23.4489 mL | 46.8977 mL | 117.2443 mL |
| 5 mM | 0.9380 mL | 4.6898 mL | 9.3795 mL | 23.4489 mL | |
| 10 mM | 0.4690 mL | 2.3449 mL | 4.6898 mL | 11.7244 mL | |
| 15 mM | 0.3127 mL | 1.5633 mL | 3.1265 mL | 7.8163 mL | |
| 20 mM | 0.2345 mL | 1.1724 mL | 2.3449 mL | 5.8622 mL | |
| 25 mM | 0.1876 mL | 0.9380 mL | 1.8759 mL | 4.6898 mL | |
| 30 mM | 0.1563 mL | 0.7816 mL | 1.5633 mL | 3.9081 mL | |
| 40 mM | 0.1172 mL | 0.5862 mL | 1.1724 mL | 2.9311 mL | |
| 50 mM | 0.0938 mL | 0.4690 mL | 0.9380 mL | 2.3449 mL | |
| 60 mM | 0.0782 mL | 0.3908 mL | 0.7816 mL | 1.9541 mL | |
| 80 mM | 0.0586 mL | 0.2931 mL | 0.5862 mL | 1.4656 mL | |
| 100 mM | 0.0469 mL | 0.2345 mL | 0.4690 mL | 1.1724 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
N-(Ketocaproyl)-DL-homoserine lactone Related Classifications
HY-129405 Related Classifications
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