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Pathways Recommended:	Stem Cell/Wnt Cell Cycle/DNA Damage

Results for "

human epidermal carcinoma cell

" in MedChemExpress (MCE) Product Catalog:

By Targets:	EGFR (1) Apoptosis (2) Bacterial (1) CDK (1) Cytochrome P450 (1) Environmental Pollutants (1) mRNA (1) Reference Standards (1)
By Research Areas:	Cancer (4) Infection (1)
Oligonucleotides:	mRNA (1)

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Natural
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Oligonucleotides

Targets Recommended: EGFR Programmed Cell Death 4 (PDCD4) Itk TOPK NAMPT ALCAM/CD166 GDNF Receptor BCL6 Tim3 VISTA BMI1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0128

Sclareol 3 Publications Verification	Environmental Pollutants Apoptosis	Cancer
Sclareol is isolated from Salvia sclarea with anticarcinogenic activity. Sclareol shows strong cytotoxic activity against mouse leukemia (P-388), human epidermal carcinoma (KB) cells and human leukemia cell lines. Sclareol induces cell apoptosis .

HY-174779

Human AREG mRNA	mRNA	Cancer
Human AREG mRNA encodes the human amphiregulin (AREG) protein, a member of the epidermal growth factor family. AREG interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells, and inhibits the growth of certain aggressive carcinoma cell lines. It also functions in mammary gland, oocyte and bone tissue development.

HY-N0128R

Sclareol (Standard)	Reference Standards Apoptosis	Cancer
Sclareol (Standard) is the analytical standard of Sclareol. This product is intended for research and analytical applications. Sclareol is isolated from Salvia sclarea with anticarcinogenic activity. Sclareol shows strong cytotoxic activity against mouse leukemia (P-388), human epidermal carcinoma (KB) cells and human leukemia cell lines. Sclareol induces cell apoptosis .

HY-181923

IMP-Zn	EGFR CDK Cytochrome P450	Cancer
IMP-Zn is a pyrazole-hydrazone Schiff base zinc (II) complex. IMP-Zn exhibits significant antiproliferative activity against human colorectal cancer cells and induces cell cycle arrest. IMP-Zn shows stronger binding affinity than its free ligand IMP towards three cancer-related protein targets: EGFR kinase 1M17, cytochrome P450 3RUK, and CDK inhibitor 6GUE. IMP-Zn can be used in studies related to colorectal cancer .

HY-N9907

7,3′-Dihydroxy-8,4′-dimethoxyisoflavone	Bacterial	Infection
7,3′-Dihydroxy-8,4′-dimethoxyisoflavone is an isoflavone Antibacterial agent. 7,3′-Dihydroxy-8,4′-dimethoxyisoflavone is isolated from the stems of S. parviflorus. 7,3′-Dihydroxy-8,4′-dimethoxyisoflavone exhibits weak antibacterial activity against Gram-positive and Gram-negative bacterial strains. 7,3′-Dihydroxy-8,4′-dimethoxyisoflavone can be used in the research of bacterial infections .

Sclareol 3 Publications Verification	Structural Classification Classification of Application Fields Terpenoids Labiatae Ulex europaeus L. Diterpenoids Plants Disease Research Fields Oxytropis falcata Bunge Source Classification Cancer	Environmental Pollutants Apoptosis
Sclareol is isolated from Salvia sclarea with anticarcinogenic activity. Sclareol shows strong cytotoxic activity against mouse leukemia (P-388), human epidermal carcinoma (KB) cells and human leukemia cell lines. Sclareol induces cell apoptosis .

Sclareol (Standard)	Structural Classification Terpenoids Labiatae Ulex europaeus L. Diterpenoids Plants Oxytropis falcata Bunge Source Classification	Reference Standards Apoptosis
Sclareol (Standard) is the analytical standard of Sclareol. This product is intended for research and analytical applications. Sclareol is isolated from Salvia sclarea with anticarcinogenic activity. Sclareol shows strong cytotoxic activity against mouse leukemia (P-388), human epidermal carcinoma (KB) cells and human leukemia cell lines. Sclareol induces cell apoptosis .

7,3′-Dihydroxy-8,4′-dimethoxyisoflavone	Structural Classification Flavonoids Spatholobus parviflorus (Roxb. ex G. Don) Kuntze Flavones Phenols Polyphenols Plants Fabaceae Source Classification	Bacterial
7,3′-Dihydroxy-8,4′-dimethoxyisoflavone is an isoflavone Antibacterial agent. 7,3′-Dihydroxy-8,4′-dimethoxyisoflavone is isolated from the stems of S. parviflorus. 7,3′-Dihydroxy-8,4′-dimethoxyisoflavone exhibits weak antibacterial activity against Gram-positive and Gram-negative bacterial strains. 7,3′-Dihydroxy-8,4′-dimethoxyisoflavone can be used in the research of bacterial infections .

Cat. No.	Product Name		Classification

HY-174779

Human AREG mRNA		mRNA
Human AREG mRNA encodes the human amphiregulin (AREG) protein, a member of the epidermal growth factor family. AREG interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells, and inhibits the growth of certain aggressive carcinoma cell lines. It also functions in mammary gland, oocyte and bone tissue development.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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human epidermal carcinoma cell

Inhibitors & Agonists

NaturalProducts

Oligonucleotides

Natural
Products