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Results for "

lipopeptide antibiotic

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (20) Bacterial (18) Drug-Linker Conjugates for ADC (1) Endogenous Metabolite (3) Fungal (4) Isotope-Labeled Compounds (2) Phospholipase (1)
By Research Areas:	Cancer (1) Infection (24)

Inhibitors & Agonists

Peptides

Natural
Products

Isotope-Labeled Compounds

Targets Recommended: Antibiotic

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0108

Daptomycin 20+ Cited Publications LY146032	Bacterial Antibiotic	Infection Cancer
Daptomycin is a lipopeptide antibiotic with rapid in vitro bactericidal activity against gram-positive organisms.

HY-A0248A

Polymyxin B1 1 Publications Verification	Bacterial	Infection
Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment .

HY-P3884

Arylomycin A2	Bacterial Antibiotic	Infection
Arylomycin A2, an *antibiotic* (Antibiotic), is a lipopeptide type I signal peptidase (SPase I) inhibitor. Arylomycin A2 has antibacterial effects .

HY-P2233

Globomycin	Bacterial Antibiotic	Infection
Globomycin is a lipopeptide antibiotic and a signal peptidase II (LspA) inhibitor. Globomycin inhibits processing of the prolipoprotein by binding irreversibly to the peptidase. Globomycin has toxic for the mollicute *Spiroplasma melliferum* with a MIC in the range 6.25-12.5 μM .

HY-P3078

Amphomycin	Bacterial Antibiotic	Infection
Amphomycin is a lipopeptide antibiotic that inhibits peptidoglycan synthesis and blocks cell wall development. Amphomycin exhibits potent antibacterial activities against methicillin-resistant S. aureus (MRSA), vancomycin-resistant enterococci (VRE), penicillin-gentamicin-erythromycin-resistant S. pneumonia, and linezolid-quinupristin-dalfopristin-resistant enterococci .

HY-P3511

Friulimicin D	Bacterial	Infection
Friulimicin D, a lipopeptide antibiotic, like Friulimicin B, is isolated from the actinomycete Actinoplanes friuliensis .

HY-125723

Echinocandin B SL 7810; A-30912 A	Endogenous Metabolite Fungal Antibiotic	Infection
Echinocandin B (SL 7810) is a lipopeptide antifungal *antibiotic. Echinocandin B is produced by Aspergillus nidulans. Echinocandin B inhibits β-1,3-glucan* activity, thereby blocking the biosynthesis of fungal cell walls. Echinocandin B exhibits activity against a variety of Aspergillus species .

HY-113560

Plipastatin B1	Antibiotic Fungal Phospholipase	Infection
Plipastatin B1 is a lipopeptide antibiotic, an inhibitor of phospholipase A₂ (PLA2), which has antifungal activity .

HY-P1974

FR 901379 WF11899A	Antibiotic	Infection
FR901379 (WF11899A) is a novel echinocandin-type lipopeptide antibiotic. FR901379 is primarily produced by mutant strain M-7 of Coleophoma empetri F-11899 (FERM BP-2635) .

HY-146535S

Daptomycin-d5 TFA LY146032-d₅ TFA	Isotope-Labeled Compounds Antibiotic Bacterial	Infection
Daptomycin-d₅ (LY146032-d₅) TFA is the deuterium labeled Daptomycin TFA. Daptomycin TFA is a lipopeptide antibiotic with rapid in vitro bactericidal activity against gram-positive organisms .

HY-186048

MC-VC-PAB-Daptomycin	Drug-Linker Conjugates for ADC	Infection
MC-VC-PAB-Daptomycin (Compound 54) is the linker-payload of an antibody-drug conjugate (ADC). β-Glucuronide-dPBD-PEG6-NH2 is composed of Daptomycin (HY-13631), a lipopeptide antibiotic, and the linker .

HY-178952

Anti-infective agent 12	Bacterial	Infection
Anti-infective agent 12 (Compound A09) is a competitive inhibitor of type I signal peptidease (SPase I), with an IC₅₀ of 4.475 μM and a K_d of 16.3 μM. Anti-infective agent 12 has the ability to disrupt bacterial membranes and remove biofilms. Anti-infective agent 12 exhibits potent bactericidal activity against Gram-positive bacteria, with MIC values of 4, 4, 8, and 8 μg/mL for Staphylococcus aureus, Enterococcus faecalis, Enterococcus faecium, and Streptococcus suis, respectively. Anti-infective agent 12 remains effective against multi-drug resistant strains, but has weaker activity against Gram-negative bacteria (such as Escherichia coli and Salmonella), with MIC values > 64 μg/mL. Anti-infective agent 12 has low hemolytic activity and shows significant efficacy in mouse skin infection models .

HY-N10585

Malacidin B	Antibiotic Bacterial	Infection
Malacidin B is a macrocyclic lipopeptide antibiotic that shows antibacterial activity in a calcium-dependent manner .

HY-N14464

Pneumocandin A1	Antibiotic Bacterial	Infection
Pneumocandin A1 is a lipopeptide antibiotic. Pneumocandin A1 has a strong anti-Candida effect. Pneumocandin A1 has the effect of inhibiting the synthesis of 1,3 early-glucan in vitro, with an IC₅₀ of 0.07-0.5 μg/mL .

HY-N5190

Enamidonin	Antibiotic Bacterial	Infection
Enamidonin is a lipopeptide antibiotic. Enamidonin inhibits EGF-dependent [ ³H] thymidine involvement in Balb/MK cells (IC₅₀ is 10 μg/mL), and it can restore the deformed SRCTS-NRK form to the normal flat form (ED50 is 10 μg/mL). No antimicrobial activity .

HY-N14466

Pneumocandin A3	Antibiotic Bacterial	Infection
Pneumocandin A3 is a lipopeptide antibiotic. Pneumocandin A3 has a strong anti-Candida effect. Pneumocandin A3 has the effect of inhibiting the synthesis of 1,3 early-glucan in vitro, with an IC₅₀ of 0.07-0.5 μg/mL .

HY-N14467

Pneumocandin A4	Antibiotic Bacterial	Infection
Pneumocandin A4 is a lipopeptide antibiotic. Pneumocandin A4 has a strong anti-Candida effect. Pneumocandin A4 has the effect of inhibiting the synthesis of 1,3 early-glucan in vitro, with an IC₅₀ of 0.07-0.5 μg/mL .

HY-N14468

Pneumocandin B2	Antibiotic Bacterial	Infection
Pneumocandin B2 is a lipopeptide antibiotic. Pneumocandin B2 has a strong anti-Candida effect. Pneumocandin B2 has the effect of inhibiting the synthesis of 1,3 early-glucan in vitro, with an IC₅₀ of 0.07-0.5 μg/mL .

HY-N14465

Pneumocandin A2	Antibiotic Bacterial	Infection
Pneumocandin A2 is a lipopeptide antibiotic. Pneumocandin A2 has a strong anti-Candida effect. Pneumocandin A2 has the effect of inhibiting the synthesis of 1,3 early-glucan in vitro, with an IC₅₀ of 0.07-0.5 μg/mL .

HY-N15117

Polymyxin P1	Antibiotic Bacterial	Infection
Polymyxin P1 is a lipopeptide antibiotic belonging to the Polymyxin family, and it is a secondary metabolite produced by the rhizosphere bacterium Paenibacillus polymyxa M-1. Polymyxin P1 binds to bacterial outer membrane lipopolysaccharides, permeabilizes cell membranes, and induces dense protrusions on the cell surface of phytopathogenic Erwinia strains. Polymyxin P1 inhibits the growth of phytopathogenic Erwinia amylovora and E. carotovora. Polymyxin P1 can be used for the research of fire blight and soft rot .

HY-B0108AS

Daptomycin-d5 LY146032-d₅	Isotope-Labeled Compounds Antibiotic Bacterial	Infection Others
Daptomycin-d₅ (LY146032-d₅) is the deuterium labeled Daptomycin (HY-B0108). Daptomycin is a lipopeptide antibiotic with rapid in vitro bactericidal activity against gram-positive organisms.

HY-125723B

Echinocandin B (purity>65%) SL 7810 (purity>65%); A-30912 A (purity>65%)	Antibiotic Fungal Endogenous Metabolite	Infection
Echinocandin B (purity>65%) (SL 7810 (purity>65%)) is a lipopeptide antifungal *antibiotic. Echinocandin B (purity>65%) is produced by Aspergillus nidulans. Echinocandin B (purity>65%) inhibits β-1,3-glucan* activity, thereby blocking the biosynthesis of fungal cell walls. Echinocandin B (purity>65%) exhibits activity against a variety of Aspergillus species .

HY-125723A

Echinocandin B (purity>85%) SL 7810 (purity>85%); A-30912 A (purity>85%)	Antibiotic Fungal Endogenous Metabolite	Infection
Echinocandin B (purity>85%) (SL 7810 (purity>85%)) is a lipopeptide antifungal *antibiotic. Echinocandin B (purity>85%) is produced by Aspergillus nidulans. Echinocandin B (purity>85%) inhibits β-1,3-glucan* activity, thereby blocking the biosynthesis of fungal cell walls. Echinocandin B (purity>85%) exhibits activity against a variety of Aspergillus species .

HY-N15117A

Polymyxin P1 TFA	Antibiotic Bacterial	Infection
Polymyxin P1 TFA is a lipopeptide antibiotic belonging to the Polymyxin family, and it is a secondary metabolite produced by the rhizosphere bacterium Paenibacillus polymyxa M-1. Polymyxin P1 TFA binds to bacterial outer membrane lipopolysaccharides, permeabilizes cell membranes, and induces dense protrusions on the cell surface of phytopathogenic Erwinia strains. Polymyxin P1 TFA inhibits the growth of phytopathogenic Erwinia amylovora and E. carotovora. Polymyxin P1 TFA can be used for the research of fire blight and soft rot .

Cat. No.	Product Name	Target	Research Area

HY-B0108

Daptomycin 20+ Cited Publications LY146032	Bacterial Antibiotic	Infection Cancer
Daptomycin is a lipopeptide antibiotic with rapid in vitro bactericidal activity against gram-positive organisms.

HY-A0248A

Polymyxin B1 1 Publications Verification	Bacterial	Infection
Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment .

HY-P3884

Arylomycin A2	Bacterial Antibiotic	Infection
Arylomycin A2, an *antibiotic* (Antibiotic), is a lipopeptide type I signal peptidase (SPase I) inhibitor. Arylomycin A2 has antibacterial effects .

HY-P2233

Globomycin	Bacterial Antibiotic	Infection
Globomycin is a lipopeptide antibiotic and a signal peptidase II (LspA) inhibitor. Globomycin inhibits processing of the prolipoprotein by binding irreversibly to the peptidase. Globomycin has toxic for the mollicute *Spiroplasma melliferum* with a MIC in the range 6.25-12.5 μM .

HY-P3078

Amphomycin	Bacterial Antibiotic	Infection
Amphomycin is a lipopeptide antibiotic that inhibits peptidoglycan synthesis and blocks cell wall development. Amphomycin exhibits potent antibacterial activities against methicillin-resistant S. aureus (MRSA), vancomycin-resistant enterococci (VRE), penicillin-gentamicin-erythromycin-resistant S. pneumonia, and linezolid-quinupristin-dalfopristin-resistant enterococci .

HY-P3511

Friulimicin D	Bacterial	Infection
Friulimicin D, a lipopeptide antibiotic, like Friulimicin B, is isolated from the actinomycete Actinoplanes friuliensis .

HY-113560

Plipastatin B1	Antibiotic Fungal Phospholipase	Infection
Plipastatin B1 is a lipopeptide antibiotic, an inhibitor of phospholipase A₂ (PLA2), which has antifungal activity .

HY-P1974

FR 901379 WF11899A	Antibiotic	Infection
FR901379 (WF11899A) is a novel echinocandin-type lipopeptide antibiotic. FR901379 is primarily produced by mutant strain M-7 of Coleophoma empetri F-11899 (FERM BP-2635) .

HY-N10585

Malacidin B	Antibiotic Bacterial	Infection
Malacidin B is a macrocyclic lipopeptide antibiotic that shows antibacterial activity in a calcium-dependent manner .

HY-N15117

Polymyxin P1	Antibiotic Bacterial	Infection
Polymyxin P1 is a lipopeptide antibiotic belonging to the Polymyxin family, and it is a secondary metabolite produced by the rhizosphere bacterium Paenibacillus polymyxa M-1. Polymyxin P1 binds to bacterial outer membrane lipopolysaccharides, permeabilizes cell membranes, and induces dense protrusions on the cell surface of phytopathogenic Erwinia strains. Polymyxin P1 inhibits the growth of phytopathogenic Erwinia amylovora and E. carotovora. Polymyxin P1 can be used for the research of fire blight and soft rot .

HY-N15117A

Polymyxin P1 TFA	Antibiotic Bacterial	Infection
Polymyxin P1 TFA is a lipopeptide antibiotic belonging to the Polymyxin family, and it is a secondary metabolite produced by the rhizosphere bacterium Paenibacillus polymyxa M-1. Polymyxin P1 TFA binds to bacterial outer membrane lipopolysaccharides, permeabilizes cell membranes, and induces dense protrusions on the cell surface of phytopathogenic Erwinia strains. Polymyxin P1 TFA inhibits the growth of phytopathogenic Erwinia amylovora and E. carotovora. Polymyxin P1 TFA can be used for the research of fire blight and soft rot .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B0108

Daptomycin 20+ Cited Publications LY146032	Infection Structural Classification Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Mammalian Cell Culture Antibacterial Disease Research Disease Research Fields Source Classification	Bacterial Antibiotic
Daptomycin is a lipopeptide antibiotic with rapid in vitro bactericidal activity against gram-positive organisms.

HY-A0248A

Polymyxin B1 1 Publications Verification	Infection Microorganisms Classification of Application Fields Antibiotics Antibacterial Disease Research Disease Research Fields Other Antibiotics Source Classification	Bacterial
Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment .

HY-125723

Echinocandin B SL 7810; A-30912 A	Structural Classification Monophenols Microorganisms Phenols Source Classification	Endogenous Metabolite Fungal Antibiotic
Echinocandin B (SL 7810) is a lipopeptide antifungal *antibiotic. Echinocandin B is produced by Aspergillus nidulans. Echinocandin B inhibits β-1,3-glucan* activity, thereby blocking the biosynthesis of fungal cell walls. Echinocandin B exhibits activity against a variety of Aspergillus species .

HY-P1974

FR 901379 WF11899A	Microorganisms Antibiotics Other Antibiotics Source Classification	Antibiotic
FR901379 (WF11899A) is a novel echinocandin-type lipopeptide antibiotic. FR901379 is primarily produced by mutant strain M-7 of Coleophoma empetri F-11899 (FERM BP-2635) .

HY-N10585

Malacidin B	Natural Products Microorganisms	Antibiotic Bacterial
Malacidin B is a macrocyclic lipopeptide antibiotic that shows antibacterial activity in a calcium-dependent manner .

HY-N14464

Pneumocandin A1	Microorganisms Antibiotics Source Classification	Antibiotic Bacterial
Pneumocandin A1 is a lipopeptide antibiotic. Pneumocandin A1 has a strong anti-Candida effect. Pneumocandin A1 has the effect of inhibiting the synthesis of 1,3 early-glucan in vitro, with an IC₅₀ of 0.07-0.5 μg/mL .

HY-N5190

Enamidonin	Microorganisms Antibiotics Other Antibiotics Source Classification	Antibiotic Bacterial
Enamidonin is a lipopeptide antibiotic. Enamidonin inhibits EGF-dependent [ ³H] thymidine involvement in Balb/MK cells (IC₅₀ is 10 μg/mL), and it can restore the deformed SRCTS-NRK form to the normal flat form (ED50 is 10 μg/mL). No antimicrobial activity .

HY-N14466

Pneumocandin A3	Monophenols Microorganisms Antibiotics Phenols Source Classification	Antibiotic Bacterial
Pneumocandin A3 is a lipopeptide antibiotic. Pneumocandin A3 has a strong anti-Candida effect. Pneumocandin A3 has the effect of inhibiting the synthesis of 1,3 early-glucan in vitro, with an IC₅₀ of 0.07-0.5 μg/mL .

HY-N14467

Pneumocandin A4	Monophenols Microorganisms Antibiotics Phenols Source Classification	Antibiotic Bacterial
Pneumocandin A4 is a lipopeptide antibiotic. Pneumocandin A4 has a strong anti-Candida effect. Pneumocandin A4 has the effect of inhibiting the synthesis of 1,3 early-glucan in vitro, with an IC₅₀ of 0.07-0.5 μg/mL .

HY-N14468

Pneumocandin B2	Monophenols Microorganisms Phenols Source Classification	Antibiotic Bacterial
Pneumocandin B2 is a lipopeptide antibiotic. Pneumocandin B2 has a strong anti-Candida effect. Pneumocandin B2 has the effect of inhibiting the synthesis of 1,3 early-glucan in vitro, with an IC₅₀ of 0.07-0.5 μg/mL .

HY-N14465

Pneumocandin A2	Natural Products Microorganisms Source Classification	Antibiotic Bacterial
Pneumocandin A2 is a lipopeptide antibiotic. Pneumocandin A2 has a strong anti-Candida effect. Pneumocandin A2 has the effect of inhibiting the synthesis of 1,3 early-glucan in vitro, with an IC₅₀ of 0.07-0.5 μg/mL .

HY-N15117

Polymyxin P1	Structural Classification Natural Products Microorganisms Source Classification	Antibiotic Bacterial
Polymyxin P1 is a lipopeptide antibiotic belonging to the Polymyxin family, and it is a secondary metabolite produced by the rhizosphere bacterium Paenibacillus polymyxa M-1. Polymyxin P1 binds to bacterial outer membrane lipopolysaccharides, permeabilizes cell membranes, and induces dense protrusions on the cell surface of phytopathogenic Erwinia strains. Polymyxin P1 inhibits the growth of phytopathogenic Erwinia amylovora and E. carotovora. Polymyxin P1 can be used for the research of fire blight and soft rot .

HY-125723B

Echinocandin B (purity>65%) SL 7810 (purity>65%); A-30912 A (purity>65%)	Structural Classification Monophenols Microorganisms Phenols Source Classification	Antibiotic Fungal Endogenous Metabolite
Echinocandin B (purity>65%) (SL 7810 (purity>65%)) is a lipopeptide antifungal *antibiotic. Echinocandin B (purity>65%) is produced by Aspergillus nidulans. Echinocandin B (purity>65%) inhibits β-1,3-glucan* activity, thereby blocking the biosynthesis of fungal cell walls. Echinocandin B (purity>65%) exhibits activity against a variety of Aspergillus species .

HY-125723A

Echinocandin B (purity>85%) SL 7810 (purity>85%); A-30912 A (purity>85%)	Structural Classification Monophenols Microorganisms Phenols Source Classification	Antibiotic Fungal Endogenous Metabolite
Echinocandin B (purity>85%) (SL 7810 (purity>85%)) is a lipopeptide antifungal *antibiotic. Echinocandin B (purity>85%) is produced by Aspergillus nidulans. Echinocandin B (purity>85%) inhibits β-1,3-glucan* activity, thereby blocking the biosynthesis of fungal cell walls. Echinocandin B (purity>85%) exhibits activity against a variety of Aspergillus species .

Cat. No.	Product Name	Chemical Structure

HY-146535S

Daptomycin-d5 TFA
Daptomycin-d₅ (LY146032-d₅) TFA is the deuterium labeled Daptomycin TFA. Daptomycin TFA is a lipopeptide antibiotic with rapid in vitro bactericidal activity against gram-positive organisms .

HY-B0108AS

Daptomycin-d5
Daptomycin-d₅ (LY146032-d₅) is the deuterium labeled Daptomycin (HY-B0108). Daptomycin is a lipopeptide antibiotic with rapid in vitro bactericidal activity against gram-positive organisms.

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lipopeptide antibiotic

Inhibitors & Agonists

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Isotope-Labeled Compounds

Natural
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