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oxidation+reaction

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27

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5

Biochemical Assay Reagents

2

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5

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3

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W007801
    Tetrapropylammonium perruthenate

    TPAP

    		 Biochemical Assay Reagents Others
    Tetrapropylammonium perruthenate (TPAP) is an organic compound commonly used as a catalyst and oxidizing agent. It can play an oxidation role in some organic synthesis reactions, and can catalyze the oxidation reactions of olefins and aromatic compounds. In addition, the compound is widely used in some industrial production areas, such as in the application of plastics, rubber and textile manufacturing processes.
    Tetrapropylammonium perruthenate
  • HY-113110
    Cysteinylglycine

    L-Cysteinylglycine; Cys-Gly; H-Cys-Gly-OH

    		 Endogenous Metabolite Reactive Oxygen Species (ROS) DNA/RNA Synthesis Cardiovascular Disease Cancer
    Cysteinylglycine (L-Cysteinylglycine; Cys-Gly) is a dipeptide formed by the peptide bond linkage between cysteine (Cysteine) and glycine (Glycine). Cysteinylglycine is an important metabolic intermediate in the human body, mainly derived from the degradation of glutathione (GSH). Cysteinylglycine reduces ferric iron to ferrous iron, drives the redox cycle of iron, generates reactive oxygen species (ROS), stimulates oxidative reactions, induces lipid peroxidation of human plasma LDL lipoproteins, and causes oxidative damage to DNA bases. Cysteinylglycine can be used as a biomarker to evaluate ischemic heart disease, breast cancer and other conditions .
    Cysteinylglycine
  • HY-153006
    2,7-Dichlorodihydrofluorescein
    5+ Cited Publications

    DCFH2

    		 Biochemical Assay Reagents Others
    2,7-Dichlorodihydrofluorescein (DCFH2) is a non-fluorescent reactive oxygen species (ROS) probe with an excitation wavelength of 485-500 nm and an emission wavelength of 515-530 nm. 2,7-Dichlorodihydrofluorescein is first hydrolyzed by intracellular esterases and then oxidized by ROS to generate non-biomembrane-permeable, highly fluorescent 2,7-dichlorofluorescein (DCF). The fluorescence intensity of DCF is positively correlated with the ROS concentration. 2,7-Dichlorodihydrofluorescein can undergo oxidation reactions with a variety of ROS (such as ·OH, H2O2, ONOO -, etc.) and is used to quantitatively detect the level of oxidative stress inside and outside cells. It is suitable for oxidative stress analysis in in vitro cell models and in vivo targeted delivery (such as liver-targeted liposomes) .
    2,7-Dichlorodihydrofluorescein
  • HY-P3185
    beta-Galactose dehydrogenase

    		Biochemical Assay Reagents Metabolic Disease
    Beta-galactose dehydrogenase is a selective catalyst for β-galactose. Under pH 8.6 conditions, beta-galactose dehydrogenase catalyzes the oxidation of β-galactose, produced by the hydrolysis of lactose by β-galactosidase, with nicotinamide adenine dinucleotide (NAD) to produce reduced nicotinamide adenine dinucleotide (NADH). Beta-galactose dehydrogenase specifically mediates this oxidation reaction for the quantitative detection of the substrate, used in the analysis of lactose concentration in samples such as breast milk .
    beta-Galactose dehydrogenase
  • HY-W034344
    Sodium methanesulfonate

    		Biochemical Assay Reagents Others
    Sodium methanesulfonate is a hygroscopic atmospheric aerosol, which typically forms from the reaction of methanesulfonic acid with sodium chloride or sea salt particles. Sodium methanesulfonate can serve as a substrate for oxidation reactions, undergoing heterogeneous oxidation by hydroxyl radicals at the air-aerosol interface, thereby initiating subsequent aerosol-phase chain reactions. Sodium methanesulfonate exhibits significant temperature-dependent deliquescence and efflorescence properties; particularly at lower temperatures relevant to the troposphere, its deliquescence and efflorescence relative humidity increase accordingly .
    Sodium methanesulfonate
  • HY-B1008A
    4-Aminobenzoic acid potassium
    1 Publications Verification

    PABA potassium; p-Aminobenzoic acid potassium

    		 Endogenous Metabolite Cardiovascular Disease Neurological Disease
    4-Aminobenzoic acid (PABA) potassium is a modifier of catecholamine oxidation reactions. 4-Aminobenzoic acid potassium is promising for research of Parkinson's disease and hypertension .
    4-Aminobenzoic acid potassium
  • HY-113033
    Pentosidine

    		Others Biochemical Assay Reagents Neurological Disease Metabolic Disease Inflammation/Immunology
    Pentosidine is a fluorescent advanced glycation end product (AGE) and cross-linker. Pentosidine is a fluorescent cross-linked structure formed by lysine and arginine in sugar oxidation reactions, and it is commonly found in collagen, skin, bone, lens and plasma proteins . Pentosidine is used in research related to type 1 diabetes, brown cataracts, rheumatoid arthritis, atherosclerosis and neurodegenerative diseases .
    Pentosidine
  • HY-112841
    PTZ-343

    3-(10′-Phenothiazinyl)propane-1-sulfonate sodium; SPTZ sodium

    		 Fluorescent Dye Cancer
    PTZ-343 is a potent enhancer of Luminol (HY-15922). PTZ-343 greatly increases the light output of the peroxidase-catalyzed luminol chemiluminescent oxidation reaction (>80%) .
    PTZ-343
  • HY-Y0396
    N-Hydroxyphthalimide

    		Biochemical Assay Reagents Survivin Bcl-2 Family Caspase Apoptosis mTOR Akt Cancer
    N-Hydroxyphthalimide is a blocking agent and catalyst. N-Hydroxyphthalimide promotes oxidation reactions by generating PINO free radicals and activating hydrogen atom transfer processes. N-Hydroxyphthalimide reduces the expression of anti-apoptotic proteins Survivin and Bcl-xL and activates caspase 9 and caspase 3. N-Hydroxyphthalimide induces Apoptosis. N-Hydroxyphthalimide inhibits the phosphorylation of mTOR (Ser2448, Ser2481) and Akt (Ser473). N-Hydroxyphthalimide has anticancer effects against breast and colon cancer .
    N-Hydroxyphthalimide
  • HY-Y0607S1
    4-Nitrobenzoic acid-d2

    		Isotope-Labeled Compounds Drug Intermediate Others
    4-Nitrobenzoic acid-d2 is the deuterium labeled 4-Nitrobenzoic acid (HY-Y0607). 4-Nitrobenzoic acid acts as a redox mediator and electron transfer promoter. 4-Nitrobenzoic acid accepts electrons from reduced glucose oxidase and transfers them to the electrode to facilitate the glucose oxidation reaction, while minimizing the formation of protonated amino groups .
    4-Nitrobenzoic acid-d2
  • HY-113110A
    Cysteinylglycine TFA

    L-Cysteinylglycine TFA; Cys-Gly TFA; H-Cys-Gly-OH TFA

    		 Endogenous Metabolite Reactive Oxygen Species (ROS) DNA/RNA Synthesis Cardiovascular Disease Cancer
    Cysteinylglycine (L-Cysteinylglycine; Cys-Gly) TFA is a dipeptide formed by the peptide bond connection of cysteine and glycine. Cysteinylglycine TFA is an important metabolic intermediate in the human body, mainly derived from the degradation of glutathione (GSH). Cysteinylglycine TFA can reduce trivalent iron to divalent iron, driving the redox cycle of iron, generating reactive oxygen species (ROS), stimulating oxidative reactions, inducing lipid peroxidation in human plasma LDL lipoproteins, and causing oxidative damage to DNA base. Cysteinylglycine TFA can be used as a biomarker to assess ischemic heart disease and breast cancer, etc [1][2][3][4].
    Cysteinylglycine TFA
  • HY-W010282
    1,2-Dimethylindole

    		Drug Derivative Cancer
    1,2-Dimethylindole is an indole derivative. 1,2-Dimethylindole involves cytochrome P450-mediated oxidative reactions (e.g., hydroxylation, oxidative demethylation). 1,2-Dimethylindole is promising for research of antitumor agents and enzyme inhibitors .
    1,2-Dimethylindole
  • HY-113110R
    Cysteinylglycine (Standard)

    L-Cysteinylglycine (Standard); Cys-Gly (Standard); H-Cys-Gly-OH (Standard)

    		 Reference Standards Endogenous Metabolite Reactive Oxygen Species (ROS) DNA/RNA Synthesis Cardiovascular Disease Cancer
    Cysteinylglycine (Standard) is the analytical standard of Cysteinylglycine. This product is intended for research and analytical applications. Cysteinylglycine is a dipeptide formed by the peptide bond linkage between cysteine (Cysteine) and glycine (Glycine). Cysteinylglycine is an important metabolic intermediate in the human body, mainly derived from the degradation of glutathione (GSH). Cysteinylglycine reduces ferric iron to ferrous iron, drives the redox cycle of iron, generates reactive oxygen species (ROS), stimulates oxidative reactions, induces lipid peroxidation of human plasma LDL lipoproteins, and causes oxidative damage to DNA bases. Cysteinylglycine can be used as a biomarker to evaluate ischemic heart disease, breast cancer and other conditions .
    Cysteinylglycine (Standard)
  • HY-162135
    MAT2A-IN-14

    		Methionine Adenosyltransferase (MAT) Reactive Oxygen Species (ROS) Cancer
    MAT2A-IN-14 (compound H3) is a MAT2A inhibitor, and generates reactive oxygen species after sonication to specifically degrade cellular MAT2A via rapid oxidative reactions. Combination of MAT2A-IN-14 and sonication induces 87% MAT2A depletion in human colon cancer cell .
    MAT2A-IN-14
  • HY-Y0607S
    4-Nitrobenzoic acid-d4

    		Isotope-Labeled Compounds Drug Intermediate Others
    4-Nitrobenzoic acid-d4 is the deuterium labeled 4-Nitrobenzoic acid (HY-Y0607). 4-Nitrobenzoic acid is an oxidoreduction mediator and an electron transfer promoter. 4-Nitrobenzoic acid accepts electrons from the reduced glucose oxidase and transfers them to the electrode to promote the glucose oxidation reaction, while minimizing the formation of protonated amine groups .
    4-Nitrobenzoic acid-d4
  • HY-Y0607R
    4-Nitrobenzoic acid (Standard)

    		Reference Standards Drug Intermediate Others
    4-Nitrobenzoic acid (Standard) is the analytical standard of 4-Nitrobenzoic acid (HY-Y0607). This product is intended for research and analytical applications. 4-Nitrobenzoic acid is an oxidoreduction mediator and an electron transfer promoter. 4-Nitrobenzoic acid accepts electrons from the reduced glucose oxidase and transfers them to the electrode to promote the glucose oxidation reaction, while minimizing the formation of protonated amine groups .
    4-Nitrobenzoic acid (Standard)
  • HY-E70583
    Recombinant Ten-Eleven Translocase

    		TET Protein Others
    Recombinant Ten-Eleven Translocase is a recombinant Fe(II)- and α-ketoglutarate-dependent dioxygenase. Recombinant Ten-Eleven Translocase converts 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC), and then to 5-formylcytosine (5fC) and 5-carboxycytosine (5caC) through a series of oxidation reactions. Then, 5caC is further converted into uracil (U) through the action of a conversion agent or enzyme, and uracil (U) is converted into thymine (T) through PCR, thereby achieving single-base resolution and high-accuracy identification of DNA methylation sites .
    Recombinant Ten-Eleven Translocase
  • HY-Y0396R
    N-Hydroxyphthalimide (Standard)

    		Biochemical Assay Reagents Reference Standards Survivin Bcl-2 Family Caspase Apoptosis mTOR Akt Others
    N-Hydroxyphthalimide (Standard) is the analytical standard of N-Hydroxyphthalimide (HY-Y0396). This product is intended for research and analytical applications. N-Hydroxyphthalimide is a blocking agent and catalyst. N-Hydroxyphthalimide promotes oxidation reactions by generating PINO free radicals and activating hydrogen atom transfer processes. N-Hydroxyphthalimide reduces the expression of anti-apoptotic proteins Survivin and Bcl-xL and activates caspase 9 and caspase 3. N-Hydroxyphthalimide induces Apoptosis. N-Hydroxyphthalimide inhibits the phosphorylation of mTOR (Ser2448, Ser2481) and Akt (Ser473). N-Hydroxyphthalimide has anticancer effects against breast and colon cancer .
    N-Hydroxyphthalimide (Standard)
  • HY-D0185R
    2'-Deoxyguanosine monohydrate (Standard)

    		Endogenous Metabolite Reference Standards Metabolic Disease
    2'-Deoxyguanosine monohydrate (Standard) is the analytical standard of 2'-Deoxyguanosine monohydrate. This product is intended for research and analytical applications. 2'-Deoxyguanosine monohydrate is a nucleoside composed of guanine and deoxyribose, and is one of the basic building blocks of DNA. In the oxidation reaction mediated by singlet oxygen 1O2, the guanine base of 2'-Deoxyguanosine is easily oxidized to generate two major products, 4,8-dihydro-4-hydroxy-8-oxodG and 7,8-dihydro-8-oxodG. The oxidation products of 2'-Deoxyguanosine monohydrate may participate in DNA damage, which may affect gene expression or induce cancer .
    2'-Deoxyguanosine monohydrate (Standard)
  • HY-W768213
    2'-Deoxyguanosine monohydrate-13C5

    		Isotope-Labeled Compounds Endogenous Metabolite Metabolic Disease
    2'-Deoxyguanosine monohydrate- 13C5 is the 13C-labeled 2'-Deoxyguanosine monohydrate (HY-D0185). 2'-Deoxyguanosine monohydrate is a nucleoside composed of guanine and deoxyribose, and is one of the basic building blocks of DNA. In the oxidation reaction mediated by singlet oxygen 1O2, the guanine base of 2'-Deoxyguanosine is easily oxidized to generate two major products, 4,8-dihydro-4-hydroxy-8-oxodG and 7,8-dihydro-8-oxodG. The oxidation products of 2'-Deoxyguanosine monohydrate may participate in DNA damage, which may affect gene expression or induce cancer .
    2'-Deoxyguanosine monohydrate-13C5
  • HY-E71117
    (S)-Cheilanthifoline synthase

    		Biochemical Assay Reagents Others
    (S)-Cheilanthifoline synthase (EC 1.14.21.2) catalysing an oxidative reaction that does not incorporate oxygen into the product.
    (S)-Cheilanthifoline synthase
  • HY-E71118
    (S)-Citramalyl-CoA lyase

    		Biochemical Assay Reagents Others
    (S)-cheilanthifoline synthase (EC 1.14.21.2) catalysing an oxidative reaction that does not incorporate oxygen into the product.
    (S)-Citramalyl-CoA lyase
  • HY-E71115
    (S)-Canadine synthase

    		Biochemical Assay Reagents Others
    (S)-Canadine synthase (EC 1.14.21.5) catalysing an oxidative reaction that does not incorporate oxygen into the product. Oxidation of the methoxyphenol group of the alkaloid tetrahydrocolumbamine results in the formation of the methylenedioxy bridge of canadine.
    (S)-Canadine synthase
  • HY-P2890B
    Laccase, Trametes versicolor

    		Fungal Metabolic Disease
    Laccase, Trametes versicolor (EC 1.10.3.2), is a blue copper oxidase that reduces molecular oxygen to water. Laccase can oxidize polyphenols, methoxylated phenolic compounds, and diamines, but not tyrosine. Laccase's oxidation reaction is a single-electron reaction and produces free radicals.
    Laccase, Trametes versicolor
  • HY-P2890C
    Laccase, Rhus vernicifera

    		Fungal Metabolic Disease
    Laccase, Trametes versicolor (EC 1.10.3.2), is a blue copper oxidase that reduces molecular oxygen to water. Laccase can oxidize polyphenols, methoxylated phenolic compounds, and diamines, but not tyrosine. Laccase's oxidation reaction is a single-electron reaction and produces free radicals.
    Laccase, Rhus vernicifera
  • HY-E71131
    (S)-Stylopine synthase

    		Biochemical Assay Reagents Others
    (S)-Stylopine synthase (EC 1.14.21.1) catalyzes an oxidation reaction that does not introduce oxygen into the product. (S)-Stylopine synthase (EC 1.14.21.1) forms a second methylenedioxy bridge in the protoberberine alkaloid stylopine by oxidatively cyclizing cheilanthifoline with adjacent phenolic hydroxyl and methoxy groups.
    (S)-Stylopine synthase
  • HY-E71128
    (S)-Nandinine synthase

    		Biochemical Assay Reagents Others
    (S)-Nandinine synthase (EC 1.14.21.12) is a cytochrome P-450 heme-thiolate enzyme catalysing an oxidative reaction that does not incorporate oxygen into the product. Forms the methylenedioxy bridge of the protoberberine alkaloid (S)-Nandinine by the oxidative ring closure of adjacent phenolic and methoxy groups of (S)-Scoulerine.
    (S)-Nandinine synthase

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