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  2. Drug Derivative
  3. 1,2-Dimethylindole

1,2-Dimethylindole is an indole derivative. 1,2-Dimethylindole involves cytochrome P450-mediated oxidative reactions (e.g., hydroxylation, oxidative demethylation). 1,2-Dimethylindole is promising for research of antitumor agents and enzyme inhibitors.

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1,2-Dimethylindole

1,2-Dimethylindole Chemical Structure

CAS No. : 875-79-6

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Based on 1 publication(s) in Google Scholar

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Description

1,2-Dimethylindole is an indole derivative. 1,2-Dimethylindole involves cytochrome P450-mediated oxidative reactions (e.g., hydroxylation, oxidative demethylation). 1,2-Dimethylindole is promising for research of antitumor agents and enzyme inhibitors[1].

Molecular Weight

145.21

Formula

C10H11N

CAS No.
Appearance

Solid

SMILES

C=1C=CC2=C(C1)C=C(N2C)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Store at room temperature 3 years

In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

DMSO : 33.33 mg/mL (229.53 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.8866 mL 34.4329 mL 68.8658 mL
5 mM 1.3773 mL 6.8866 mL 13.7732 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

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Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.93%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 6.8866 mL 34.4329 mL 68.8658 mL 172.1644 mL
5 mM 1.3773 mL 6.8866 mL 13.7732 mL 34.4329 mL
10 mM 0.6887 mL 3.4433 mL 6.8866 mL 17.2164 mL
15 mM 0.4591 mL 2.2955 mL 4.5911 mL 11.4776 mL
20 mM 0.3443 mL 1.7216 mL 3.4433 mL 8.6082 mL
25 mM 0.2755 mL 1.3773 mL 2.7546 mL 6.8866 mL
30 mM 0.2296 mL 1.1478 mL 2.2955 mL 5.7388 mL
40 mM 0.1722 mL 0.8608 mL 1.7216 mL 4.3041 mL
50 mM 0.1377 mL 0.6887 mL 1.3773 mL 3.4433 mL
60 mM 0.1148 mL 0.5739 mL 1.1478 mL 2.8694 mL
80 mM 0.0861 mL 0.4304 mL 0.8608 mL 2.1521 mL
100 mM 0.0689 mL 0.3443 mL 0.6887 mL 1.7216 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
1,2-Dimethylindole
Cat. No.:
HY-W010282
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