1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Cysteinylglycine TFA

Cysteinylglycine TFA is an endogenous metabolite and used in disease diagnosis.

For research use only. We do not sell to patients.

Cysteinylglycine TFA Chemical Structure

Cysteinylglycine TFA Chemical Structure

CAS No. : 1100364-95-1

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25 mg USD 50 In-stock
50 mg USD 85 In-stock
100 mg USD 140 In-stock
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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Cysteinylglycine TFA:

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  • Biological Activity

  • Purity & Documentation

  • References

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Description

Cysteinylglycine TFA is an endogenous metabolite and used in disease diagnosis[1].

IC50 & Target[1]

Human Endogenous Metabolite

 

Molecular Weight

292.23

Formula

C7H11F3N2O5S

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(O)CNC([C@H](CS)N)=O.O=C(O)C(F)(F)F

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (855.49 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : 125 mg/mL (427.75 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.4220 mL 17.1098 mL 34.2196 mL
5 mM 0.6844 mL 3.4220 mL 6.8439 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% Saline

    Solubility: ≥ 2.08 mg/mL (7.12 mM); Clear solution

    This protocol yields a clear solution of ≥ 2.08 mg/mL (saturation unknown).

    Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (20.8 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.

    Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
  • Protocol 2

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in Saline)

    Solubility: ≥ 2.08 mg/mL (7.12 mM); Clear solution

    This protocol yields a clear solution of ≥ 2.08 mg/mL (saturation unknown).

    Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (20.8 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.

    Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 99.76%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO 1 mM 3.4220 mL 17.1098 mL 34.2196 mL 85.5491 mL
5 mM 0.6844 mL 3.4220 mL 6.8439 mL 17.1098 mL
10 mM 0.3422 mL 1.7110 mL 3.4220 mL 8.5549 mL
15 mM 0.2281 mL 1.1407 mL 2.2813 mL 5.7033 mL
20 mM 0.1711 mL 0.8555 mL 1.7110 mL 4.2775 mL
25 mM 0.1369 mL 0.6844 mL 1.3688 mL 3.4220 mL
30 mM 0.1141 mL 0.5703 mL 1.1407 mL 2.8516 mL
40 mM 0.0855 mL 0.4277 mL 0.8555 mL 2.1387 mL
50 mM 0.0684 mL 0.3422 mL 0.6844 mL 1.7110 mL
60 mM 0.0570 mL 0.2852 mL 0.5703 mL 1.4258 mL
80 mM 0.0428 mL 0.2139 mL 0.4277 mL 1.0694 mL
100 mM 0.0342 mL 0.1711 mL 0.3422 mL 0.8555 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Cysteinylglycine TFA
Cat. No.:
HY-113110A
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