Cysteinylglycine TFA

Name: Cysteinylglycine TFA
Brand: MedChemExpress
SKU: HY-113110A
Rating: 4.5 (1 reviews)

Cat. No.: HY-113110A Purity: 99.51%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Cysteinylglycine TFA is an endogenous metabolite and used in disease diagnosis.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Cysteinylglycine TFA Chemical Structure

CAS No. : 1100364-95-1

Size	Price	Stock	Quantity
25 mg	USD 50	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 85	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 140	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of Cysteinylglycine TFA:

Cysteinylglycine In-stock

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Cysteinylglycine TFA is an endogenous metabolite and used in disease diagnosis^[1].

IC₅₀ & Target^[1]

Human Endogenous Metabolite

Molecular Weight

292.23

Formula

C₇H₁₁F₃N₂O₅S

CAS No.

1100364-95-1

Appearance

Solid

Color

White to off-white

Structure Classification

Others

Initial Source

Endogenous metabolite

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture and light, under nitrogen

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

Solvent & Solubility

In Vitro:

DMSO : 250 mg/mL (855.49 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H₂O : 125 mg/mL (427.75 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.4220 mL	17.1098 mL	34.2196 mL
5 mM	0.6844 mL	3.4220 mL	6.8439 mL
10 mM	0.3422 mL	1.7110 mL	3.4220 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.08 mg/mL (7.12 mM); Clear solution

This protocol yields a clear solution of ≥ 2.08 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (20.8 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Protocol 2

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.08 mg/mL (7.12 mM); Clear solution

This protocol yields a clear solution of ≥ 2.08 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (20.8 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Protocol 3

Add each solvent one by one: 10% DMSO 90% Corn Oil
Solubility: ≥ 2.08 mg/mL (7.12 mM); Clear solution

This protocol yields a clear solution of ≥ 2.08 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (20.8 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.51%

Select Batch:

Data Sheet (273 KB) SDS (252 KB)

COA (250 KB) RP-HPLC (420 KB)

Handling Instructions (2659 KB)

References

[1]. Houghton SC, et al. Plasma B-vitamin and one-carbon metabolites and risk of breast cancer before and after folicacid fortification in the United States. Int J Cancer. 2019 Apr 15;144(8):1929-1940. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O / DMSO	1 mM	3.4220 mL	17.1098 mL	34.2196 mL	85.5491 mL
	5 mM	0.6844 mL	3.4220 mL	6.8439 mL	17.1098 mL
	10 mM	0.3422 mL	1.7110 mL	3.4220 mL	8.5549 mL
	15 mM	0.2281 mL	1.1407 mL	2.2813 mL	5.7033 mL
	20 mM	0.1711 mL	0.8555 mL	1.7110 mL	4.2775 mL
	25 mM	0.1369 mL	0.6844 mL	1.3688 mL	3.4220 mL
	30 mM	0.1141 mL	0.5703 mL	1.1407 mL	2.8516 mL
	40 mM	0.0855 mL	0.4277 mL	0.8555 mL	2.1387 mL
	50 mM	0.0684 mL	0.3422 mL	0.6844 mL	1.7110 mL
	60 mM	0.0570 mL	0.2852 mL	0.5703 mL	1.4258 mL
	80 mM	0.0428 mL	0.2139 mL	0.4277 mL	1.0694 mL
	100 mM	0.0342 mL	0.1711 mL	0.3422 mL	0.8555 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.