1. Epigenetics NF-κB Immunology/Inflammation Metabolic Enzyme/Protease
  2. Reactive Oxygen Species Methionine Adenosyltransferase (MAT)
  3. MAT2A-IN-14

MAT2A-IN-14 (compound H3) is a MAT2A inhibitor, and generates reactive oxygen species after sonication to specifically degrade cellular MAT2A via rapid oxidative reactions. Combination of MAT2A-IN-14 and sonication induces 87% MAT2A depletion in human colon cancer cell.

For research use only. We do not sell to patients.

MAT2A-IN-14 Chemical Structure

MAT2A-IN-14 Chemical Structure

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Description

MAT2A-IN-14 (compound H3) is a MAT2A inhibitor, and generates reactive oxygen species after sonication to specifically degrade cellular MAT2A via rapid oxidative reactions. Combination of MAT2A-IN-14 and sonication induces 87% MAT2A depletion in human colon cancer cell[1].

Molecular Weight

506.50

Formula

C27H24F2N4O4

SMILES

O=C1C(C2=CC=C(C3=C2)OCC4N3CCC4)=CC(C=NC(OCC)=N5)=C5N1C6=CC=C(C=C6)OC(F)F

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
MAT2A-IN-14
Cat. No.:
HY-162135
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