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Results for "

phytohemagglutinin+pha

" in MedChemExpress (MCE) Product Catalog:

11

Inhibitors & Agonists

5

Peptides

2

Natural
Products

Art. -Nr. Produktname Target Forschungsgebiete Chemical Structure
  • HY-N7038
    Phytohemagglutinin
    5+ Cited Publications

    PHA-M

    		 NF-κB COX Interleukin Related Reactive Oxygen Species (ROS) Neurological Disease Inflammation/Immunology Cancer
    Phytohemagglutinin (PHA-M), the major seed lectin of the common bean, Phaseolus vulgaris, is a T-cell activator. Phytohemagglutinin stimulates human mononuclear leukocytes, inducing the expression of ChAT mRNA and potentiating ACh synthesis. Phytohemagglutinin induces dose- and time-dependent toxicity in THP-1 monocytes/macrophages, alters cellular morphology, causes organelle dysfunction, and increases the expression of NF-κB, COX2, IL-1β .
    Phytohemagglutinin
  • HY-B1916
    Acetylspiramycin
    2 Publications Verification

    Spiramycin B; Spiramycin II; Foromacidin B

    		 Antibiotic Bacterial Parasite Infection
    Acetylspiramycin (Spiramycin B) is an effective oral macrolide antibiotic produced by Streptomyces, It can inhibit the splenic lymphocyte transformation induced by phytohemagglutinin (PHA), LPS (HY-D1056) and antigen, reduce the procoagulant activity of macrophages, have good antibacterial effect on gram-positive bacteria, and is also an effective antigenic insect agent, which can be used to fight parasitic infection .
    Acetylspiramycin
  • HY-P10956
    Colulintide

    LY3541105

    		 Amylin Receptor CGRP Receptor Metabolic Disease
    Colulintide (LY3541105) is an amylin-calcitonin dual receptor agonist with Amylin as its scaffold. Colulintide is applicable to research related to type 2 diabetes and obesity .
    Colulintide
  • HY-P10959
    Macupatide

    LY3532226

    		 Insulin Receptor Metabolic Disease
    Macupatide is a glucose-dependent insulinotropic polypeptide (GIP) receptor agonist. Macupatide improves insulin secretion responses and insulin sensitivity.Macupatide can be used for the research of type 2 diabetes .
    Macupatide
  • HY-P10959A
    Macupatide acetate

    LY3532226 acetate

    		 Insulin Receptor Metabolic Disease
    Macupatide acetate is a glucose-dependent insulinotropic polypeptide (GIP) receptor agonist. Macupatide acetate improves insulin secretion responses and insulin sensitivity.Macupatide acetate can be used for the research of type 2 diabetes .
    Macupatide acetate
  • HY-P10965
    Zovaglutide

    ZT002

    		 GLP Receptor Metabolic Disease
    Zovaglutide (ZT002) is a long-acting, selective GLP-1 receptor agonist. Zovaglutide enhances albumin binding capacity via dual fatty acid chain modification. Zovaglutide exerts metabolic effects through central and peripheral GLP-1 pathways, thereby promoting satiety, reducing caloric intake and enhancing glucose-dependent insulin secretion, with no activity against GIP or glucagon receptors. Zovaglutide can be used in research on type 2 diabetes or obesity .
    Zovaglutide
  • HY-P10964
    Tezusomant

    		GHSR Endocrinology
    Tezusomant is a growth hormone receptor antagonist. Tezusomant is promising for research on diseases caused by excessive growth hormone secretion, such as acromegaly .
    Tezusomant
  • HY-101687
    Nosantine racemate

    NPT 15392 racemate

    		 Interleukin Related Inflammation/Immunology
    Nosantine racemate is the racemate of Nosantine. Nosantine is an inducer of IL-2 or enhancer of IL-2 induction by phytohemagglutinin (PHA).
    Nosantine racemate
  • HY-B1916R
    Acetylspiramycin (Standard)

    Spiramycin B (Standard); Spiramycin II (Standard); Foromacidin B (Standard)

    		 Reference Standards Antibiotic Bacterial Parasite Infection
    Acetylspiramycin (Standard) is the analytical standard of Acetylspiramycin. This product is intended for research and analytical applications. Acetylspiramycin (Spiramycin B) is an effective oral macrolide antibiotic produced by Streptomyces, It can inhibit the splenic lymphocyte transformation induced by phytohemagglutinin (PHA), LPS (HY-D1056) and antigen, reduce the procoagulant activity of macrophages, have good antibacterial effect on gram-positive bacteria, and is also an effective antigenic insect agent, which can be used to fight parasitic infection[1][2][3][4].
    Acetylspiramycin (Standard)
  • HY-19080
    SC-45662

    		Lipoxygenase Inflammation/Immunology
    SC-45662 is a 5-lipoxygenase inhibitor. SC-45662 inhibits the response of monocytes to phytohemagglutinin (PHA). SC-45662 inhibits superoxide production in neutrophils. SC-45662 slows early changes in lung mechanics and pulmonary hypertension in a sheep model of impaired lung function. SC-45662 can be used in research on diseases of the immune system, respiratory system, etc .
    SC-45662
  • HY-N17413
    (-)-γ-Cuparenol

    		Bacterial Na+/K+ ATPase NF-κB Nuclear Factor of activated T Cells (NFAT) Cardiovascular Disease Infection Inflammation/Immunology
    (-)-γ-Cuparenol is a sesquiterpene compound with an IC50 of 23.6 μg/mL against porcine Na +/K +-ATPase. (-)-γ-Cuparenol reduces phytohemagglutinin (PHA)-induced activation of NF-AT and NF-κB in Jurkat cells. (-)-γ-Cuparenol inhibits the growth of Gram-positive bacteria and some Gram-negative bacteria. (-)-γ-Cuparenol exhibits weak inhibitory activity against Candida albicans. (-)-γ-Cuparenol is applicable for research related to immunoregulation, cardiovascular diseases and bacterial infections .
    (-)-γ-Cuparenol

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